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Tag: "estrogen" at biology news

Gene expression test reveals ER and HER-2 status of breast tumors

...r a tumor's growth is fueled by the female hormone estrogen and the role of a growth factor receptor known as ..., they employed an Affymetrix microarray to gather estrogen receptor and HER-2 receptor gene expression data from 495 breast cancer samples from seven instituti...

Selective marker found to indicate aggressive form of breast cancer

...umors lack important molecular targets such as the estrogen receptor, progesterone receptor and Her2. This no...etrospective study of breast cancer tumors lacking estrogen receptors, progesterone receptors and Her2, DiRenzo and his colleagues found extremely high amounts ...

What's in the water? Estrogenic activity documented in fish caught in Pittsburgh's rivers

...ted like estrogen, a female hormone, by binding to estrogen receptors ?the proteins within cells that render t...ayed a strong or moderate ability to bind with the estrogen receptors. Of 21 catfish extracts tested, nine displayed a similar ability to bind with the estrogen...

Brain's reward circuit activity ebbs and flows with a woman's hormonal cycle

...nd dominated by estrogen, compared to a phase when estrogen and progesterone are present. "These first pictu...rtex. Reward circuit neurons harbor receptors for estrogen and progesterone. However, how these hormones influence reward circuit activity in humans has remain...

Effect on breast tumors of DNA alternations in 3 genes described

...ot of the other genes, was more likely to occur in estrogen receptor (ER)-negative than in ER-positive tumors," said Tao. ER-positive tumors are those that express receptors for the hormone estrogen. Such tumors respond to treatments that block these receptors. "Similarly, hypermethylation of E-cadherin...

Studies to find better ways to preserve human eggs, ovarian tissue under way

... problematic because many breast cancer cells have estrogen receptors. As pieces of a puzzle come together, Dr. Song notes scientists already are developing methods to stimulate ovarian tissue to produce eggs outside the body, a process that could also make in vitro fertilization a lot more affordable. Oth...

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