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Tag: "establishes" at biology news

Research finds that circadian rhythms dominate all life functions

...analysis of data collected through several studies establishes a baseline oscillation in 98 to 99 percent of all genes through advanced computer algorithms. Most of these genes have never been previously reported as changing their expression level in a daily cycle. Some of these genes, considered "housekeeping,"...

The quest for an effective HIV vaccine presents new possibilities, challenges

...cells, replicates, spreads throughout the body and establishes HIV reservoirs in lymphatic tissues. Within weeks of exposure, virus levels peak and then decline to levels that may remain low for months or years. It is believed that CD8+ T cells--so-called killer T-cells--are responsible for this reduction in HIV...

Infection detectives use disease 'fingerprints' to track common infections in children

...d Dr. Ramilo. "This is just the first step. But it establishes a basis for us to do that." While pediatricians couldn’t perform the analysis in their offices, researchers are already thinking about a possible way they could send in the results from the chip and get the analysis back via the Internet, for exam...

MicroRNAs as tumor suppressors

... of HMGA2 expression and tumorigenesis. This paper establishes that HMGA2 is a target of let-7, and that the let-7 microRNA functions as a tumor suppressor to prevent cancer formation in healthy cells....

Cartilage discovery offers arthritis hope

... "This research, while just a beginning, at least establishes some basic scientific facts that could prove useful in future studies on osteoarthritis and related conditions." The next stage of the team's work will be to determine the structure of the thicker fibrils and examine how collagen cells manage to pr...

Twin studies reveal genetic components leading to cardiac and kidney disease

...s between the siblings in each MZ and DZ twin pair establishes what is called the index of heritability. The human genome has three billion base pairs and about 30,000 genes. O’Connor and his research team have looked at about 900 of these 30,000 genes. "We’re just scratching the surface," he said. The...

MicroRNAs can be tumor suppressors

...umorigenesis (formation of tumors). This paper establishes that HMGA2 is a target of let-7, and that the let-7 microRNA functions as a tumor suppressor to prevent cancer formation in healthy cells. ...

Researchers make nanosheets that mimic protein formation

...tein structures form in living organisms. "This establishes an important connection between two basic building blocks in biology and nanotechnology, that is, proteins and nanoparticles, and this is very exciting for assembling materials from the bottom up for a whole slew of applications ranging from drug del...

Researchers create genetically matched embryonic stem cells for transplantation

...nce on December 14. Though done in mice, the work establishes the principle of using unfertilized eggs as a source of customized embryonic stem cells that are genetically matched to the egg donor at the genes that control recognition of cells by the immune system, making them potentially useful for transplantat...

New technology addresses female fertility preservation

... Chemical and Biological Engineering. "This system establishes a core technology for human egg banks for preservation of fertility." The technology mimics the ovary and its environment. Follicles (each follicle has one egg) from mice were grown in vitro until fully matured by providing the follicles and eggs wi...

Microbes transform 'safest' PBDEs into more harmful compounds

...the environment. "This study, for the first time, establishes that microbes found in every-day settings can degrade relatively stable forms of PBDEs, making them far less stable and potentially more toxic," says Lisa Alvarez-Cohen, Ph.D., the study’s corresponding author. "It implies that current and planned ba...

New roles for growth factors: Enticing nerve cells to muscles

...les that ensure that the developing nervous system establishes proper neuronal connections." Understanding how axons find their destinations may help restore movement in people following spinal cord injury, or those with motor neuron diseases such as Lou Gehrig's disease, spinal muscle atrophy, and post-polio ...

High-resolution light microscope reveals the fundamental mechanisms of nerve communication

...e zones. In these areas it appears that bruchpilot establishes the proximity between the calcium channels and the vesicles enabling the efficient release of neurotransmitters. These studies demonstrate for the first time that resolution below a half-wavelength of visible light is no longer reserved for the elec...

Study finds evolution doesn't always favor bigger animals

...vertheless, the UCSD study is important because it establishes a firm link between climatic change and the body size of organisms, paving the way for a better understanding of the evolution of body size in fossil organisms as well as in environments that are now being impacted by global warming. "There's still...

Experimental TB drug effective against resistant and latent mycobacterium tuberculosis

...tion as well. After exposure, tuberculosis often establishes a latent infection, where the infected patient has no symptoms and is not contagious, but could become active at any time. It is estimated that nearly a third of the world's population, approximately 2 billion people, are latently infected. "The l...

Bugs expose underground carbon traffic system 10 times more important than fossil fuel burning

... did not have 13C enriched PFLAs.. This research establishes that arbuscular mycorrhizal mycelia provide a major highway in terms of transporting carbon from plants to soil. This new understanding of how both mycorrhizal mycelia and the insect population of soil impact on the transport of carbon will assist re...

New study examines how sense of smell affects mating and aggression in mice

...in. The study is important, says Shah, because it establishes a novel and hitherto unsuspected role for the MOE in regulating mating and aggressive behavior in mice. He adds that while it appears humans do not have an intact VNO, they do possess a functioning MOE. In the study, researchers compared the behav...

Researchers identify molecular anchor that allows bacterial invasion of central nervous system

...oducing a fat-sugar complex that anchors LTA, iagA establishes a link that allows bacteria to begin making its way into the nervous system. The researchers found that removing the iagA gene from the Streptococcus inhibited bacterial interactions with the blood-brain barrier, reducing mortality rates up to 90 per...

Molecular trigger for Huntington's disease found

...sent in human HD patients. "In summary, our study establishes a specific role for p53 in HD," concluded Sawa and colleagues. "As p53 is a nuclear transcription factor that regulates various mitochondrial genes and insofar as mitochondrial dysfunction appears important in HD, our findings provide a molecular mec...

Once given 'no respect,' cells' tiny RNAS take driver's seat

...y E2F1 just happens to be the gene for Myc. "This establishes a feedback loop," says Kathryn O'Donnell, Ph.D., who conducted much of the work as a graduate student in the Human Genetics Program. "Because both Myc and E2F1 increase the expression of genes that increase cell growth, the pair could be quite danger...

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