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Tag: "essential" at biology news

Researchers identify new weapon to fight deadly bacterial sepsis

... researchers demonstrated that aldose reductase is essential to that cycle. Previous work by Srivastava and his UTMB collaborators (including research described in a paper published Oct. 1 in Cancer Research) has demonstrated that blocking aldose reductase similarly can dramatically reduce the inflammation...

Malaria treatment efficacy compromised in certain HIV-positive patients

...is and a highly efficacious malaria treatment, are essential tools in areas where both diseases coexist. Furthermore, the interaction between antimalarial and antiretroviral therapies should continue to be examined in an effort to maximize the effects of therapy on both diseases and to decrease the malaria bu...

Mayo researchers discover HIV dependence on a human protein

...s have discovered that a specific human protein is essential for HIV to integrate into the human genome. Their findings show that when HIV inserts itself into a chromosome, a key step that enables it to establish a "safe haven," it requires a specific protein -- LEDGF/p75 (p75). This protein forms a molecular ...

Researchers in Montréal and the US create model of key immune-system component

...have made a major breakthrough in understanding an essential aspect of the immune system. For the first time, using a systems biology approach, they have developed a model that facilitates the study of the function of the phagosome. The phagosome is the organelle responsible for the destruction of infectious p...

New sunscreen ingredient to heal sunburn and help prevent skin cancer

...but that would not have an adverse effect on other essential cellular processes. After three years of research, the team has designed two commercially attractive prototypes which are currently in laboratory trials. The prototypes contain 'caged' iron binding sites which release the chelators only in resp...

Drug can quickly mobilize an army of cells to repair injury

...ays. "We chose G-CSF in this case because it's not essential that the treatment act quickly - the condition has been present for months before the patients are treated - and the drug already has FDA approval for medical use. We want to find out if this treatment will lead to long-lasting improvement in blood f...

Study highlights new and cheaper way to treat heroin addiction

...to prescribing dihydrocodeine tablets, it is still essential that treatment regimes are controlled and tailored to the individual. "We want to engage young people in a treatment programme which stops them from injecting drugs and running the risk of infection," he said. "Apart from the danger of contrac...

Scientists discover toxin that causes gastro disease

...cterial toxin, subtilase cytotoxin, deactivates an essential component of cells in the gastrointestinal tract. "It is unique because it cuts an essential component of the cell machinery in half, therefore disabling it," he said. As well as learning ...

Regulating the nuclear architecture of the cell

...in the cell's nucleus has profound effects on such essential functions as how and when genes are expressed. When regulation fails, genome aberrations accumulate, including repeated sequences of DNA or even entire extra chromosomes. "Our project continues to point to an understanding of genome stability in ...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...godendrocytes, the nerve-supporting cells that are essential for proper neuron function. She has been awarded a grant from the Biomedical Technology Alliance, a Milwaukee inter-institutional research group, to determine in collaboration with Brian Schmit, Ph.D., associate professor of biomedical engineering at...

Mayo discovers protein as potential tactic to prevent tumors

...ells. "Quality control within dividing cells is essential because mistakes during duplication of the genetic code can lead to cancer," says Donald Tindall, Ph.D., co-leader of the Mayo Clinic Cancer Center prostate cancer research program. "CDK2 is a key protein component in the cellular mechanism that lead...

Mutant mouse provides insights into breast cancer

...t cancer. The mouse contains a mutation in a gene essential for replicating DNA in both humans and mice that i...cm4 gene is one of six related Mcm genes that play essential roles in replication and were originally discovered at Cornell in baker's yeast ( S. cerevisiae ). T...

Researchers discover that sheep need retroviruses for reproduction

...tional Academy of Sciences demonstrate enJSRVs are essential for the development of the placenta in sheep. Retroviruses are unique for their ability to permanently insert their genetic material into the DNA of host cells, he said. During evolution of mammals, some retroviruses infected the germline (cells o...

Pattern of human Ebola outbreaks linked to wildlife and climate

... rural African residents could provide information essential for protecting public health as well as comprehending the ecology of the disease. Lahm points out that there remain many unanswered questions about Ebola including how the virus spreads within and between mammal species. "Our study provides m...

Squid-inspired design could mean better handling of underwater vehicles

...ing humanity. "Reliable docking mechanisms are essential for the operation of underwater vehicles, especially in harsh environments," Mohseni said. "We set out to resolve the trade off that many researchers settle for, which is a faster, but less precise, vehicle or a boxier one that is not as fast and mo...

New dyslexia theory blames 'noise'

...xia appear to have shaky mental categories for the essential sounds that make up language. "It's harder to make a [language] task automatic when your categories are fuzzier than they ought to be to begin with," she said. "In terms of treatment, the results suggest that programs that foster the develop...

New HIV statistics indicate increasing toll of AIDS on African American community

...search to implement interventions for black MSM is essential to reversing the epidemic in this population. Promoting leadership among black MSM and sustained capacity-building investments in the organizations that serve them is critical. Efforts to address homophobia and related stigma, discrimination and vi...

Altered perception of reward in human cocaine addiction

...ness of the prefrontal cortex, a part of the brain essential for monitoring and controlling behavior," said Rita Goldstein, a psychologist at Brookhaven Lab. "These results also attest to the benefit of using sophisticated brain-imaging tools combined with sensitive behavioral, cognitive, and emotional probes ...

Researchers image molecular motor structural changes

...h Council and senior author of the paper, provided essential advice for the computational analysis and analyzed the resolutions of the final images." The researchers then took those high-resolution models and combined them with models of kinesin and microtubule structures rendered using another technology, x-...

Scientists get best look ever at water-life connection

...s interact with proteins ?even though water is the essential element for life . . . that is, not until now. Re...ot different answers on the speed with which these essential biochemical reactions take place. "A biologist will tell you that water and proteins must interact ...

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