Molecular trigger for Huntington's disease found
... This inactivation allows abnormal cancer cells to escape the cell's protective "suicide program" that would normally kill them. The researchers theorize that the lower incidence of cancer in HD patients could be caused by the protective effect of overactive p53. In the July 7, 2005, issue of Neuron, Akira...Breast tumors in mice eradicated using cancer vaccine
...the immune response. But Listeria has evolved to escape from this vacuole and survive inside the cytosol of antigen-presenting cells, where it can replicate and grow, unlike other bacteria. So, although some of the bacteria are destroyed in the vacuole that feeds the MHC class II pathway of antigen presen...Emerging staph strains found to be increasingly deadly and deceptive
...eus genes that potentially control the bacterium's escape from neutrophils. Among thousands of S. aureus genes analyzed in the five different strains used in the study, the scientists identified a large group of genes whose role in helping spread infection is unknown. RML's Frank DeLeo, Ph.D., the investiga...Creeping crinoids! Sea lilies crawl to escape predators, new video shows
...ies can creep along the ocean floor, apparently to escape from sea urchins that prey upon them. The video and related studies help paint a bigger picture of the evolution and ecology of these deep-sea creatures and their predators. University of Michigan professor of geological sciences Tomasz Baumiller w...U. of Colorado researcher identifies tracks of swimming dinosaur in Wyoming
...ies can creep along the ocean floor, apparently to escape from sea urchins that prey upon them. The video and related studies help paint a bigger picture of the evolution and ecology of these deep-sea creatures and their predators. University of Michigan professor of geological sciences Tomasz Baumiller w...Russian 'surrogate' alcohols are a killer
...health-care system. Alcohol is used as a means of escape from reality." McKee is hopeful that the Russian government has become aware of the seriousness of the problem. "Following a meeting that we had with President Putin's advisors," he said, "the president specifically mentioned the need to tackle sur...Dangerous tricksters: Some bacterie use immune cells to reproduce
...635-653). Their findings reveal that the pathogens escape the 'stomach' of the macrophages which might otherwise digest them. Action stations in the horse's lung! A bacterium has just been inhaled into a horse's bronchial tubes, and immune cells are quickly recruited to the spot to neutralise the intruder...Polymer gel can block toxic leakage problem in gene therapy
...al injection can cause the gene-bearing viruses to escape their intended target and pose risks elsewhere, th...h the researchers proposed a solution to the viral escape problem in the form of a polymer compound already employed for wound healing and for drug and gene d...Shorter colds, milder flu may follow from newly revealed immune mechanism
...und that CCL5 turns on signals that allow cells to escape virus-induced death. These signals are termed anti-apoptotic because they work against a process of programmed cell death called apoptosis. The CCL5-induced anti-apoptotic signals therefore help keep macrophages alive, which allows them to continue t...UCLA scientists discover immune response to HIV differs, even in identical twins
...f is genetically determined. ". The virus tries to escape that immune response by mutating and changing shape. The twins' targeting of the HIV was remarkably similar 17 years after infection yet their overall TCR characteristics were highly divergent. The finding, demonstrates that the interaction between ...Ocean 'dead zones' trigger sex changes in fish, posing extinction threat
...tures trapped in these zones often die. Those that escape may be more vulnerable to predators and other stresses. This new study, Wu says, suggests these zones potentially pose a third threat to these species ?an inability of their offspring to find mates and reproduce. The researchers found that low leve...Penguins okay with human visitors?for now
...ase in their hormones facilitates their ability to escape or outlast the situation. As stated, the results show no short-term negative impact of human visits, but long-term effects have not been reported. "These long-term consequences are much harder to document, especially in long-lived animals such as ...Human albumin from tobacco plants
...m plants using this technique does not involve the escape of genes through pollen transmission given that, with most crops under cultivation, the genome of the plastids is inherited maternally. More biomass in tobacco plants The tobacco plant is very easy to handle genetically and also it is great gene...Flesh-eating bacteria escape body's safety net
...s these DNA nets, thereby allowing the organism to escape the neutrophil net and spread in body tissues. Th...single gene allowed these bacteria to degrade DNA, escape neutrophil killing, and produce a spreading ulcer in the mouse infection model. Special fluorescent...Cancer cells suppress large regions of DNA by a reversible process that can be tackled
... formulated a new concept for how cancer cells can escape normal growth controls, which may have far-reaching implications for the new generation of cancer therapies. They have found large regions of DNA are 'switched off' in colon cancer. Lead researcher Associate Professor Sue Clark, of the Garvan Instit...Invasive exotic plants helped by natural enemies
...ts that invasive exotic plants thrive because they escape the natural enemies that kept them in check in their native ranges, a new study in the journal Science suggests the opposite. Exotic plants that are in the presence of their natural enemies actually do better in their introduced ranges. The research ...Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection
...the main tumor and migrate to form satellites that escape treatment and often lead to recurrence. Researchers at the Maxine Dunitz Neurosurgical Institute documented several years ago that some neural stem cells ?"immature" cells that can differentiate into central nervous system cells ?have the ability to...Synthetic molecule causes cancer cells to self-destruct
... procaspase-3 is broken. As a result, cancer cells escape destruction and grow into tumors. "We have identified a small, synthetic compound that directly activates procaspase-3 and induces apoptosis," said Paul J. Hergenrother, a professor of chemistry at the University of Illinois at Urbana-Champaign and ...New bird flu drug promises to beat the problem of resistance
...e. When this happens, the neuraminidase is able to escape from the drug and continue its job. The new class of molecule being developed by the University of Bath and CSIRO researchers blocks the action of the neuraminidase in a very different manner, by undergoing a chemical reaction with protein. Furthe......bably less capable of developing new strategies to escape predators, compared with larger-brained species. ...that being clever should help individuals avoid or escape danger ?the larger-brained chimpanzees rarely feature in the diets of predators." "Some animals' ...