Recreating 'Flowers for Algernon' with a happy ending
...memory," recalled Silva. "It was the researcher's equivalent of finding a suitcase stuffed with a million dollars." Statin drugs lower cholesterol by blocking the effects of certain fats. Because Ras requires fat to function, less fat results in less Ras. With reduced Ras activity, the brain cells are able ...Chlamydia parasite lives off our fat
...s made as Kumar and Valdivia performed the genetic equivalent of an end-run. Chlamydia is not amenable to direct genetic manipulation so the researchers moved the pathogen's genes elsewhere, inserting them into the eukaryotic cells of baker's yeast. The resulting chlamydial proteins were screened for those that...Travelers can avoid jet lag by resetting their body clocks
... evening. If they did this for the number of days equivalent to the number of time zones crossed, then they should be completely adjusted to the new time zone before they fly," she added. "However, even following the schedule for a few days before flying would reduce the jet lag experienced upon arrival at th...Getting old? Slowing down? Blame inefficient mitochondria
Mitochondria are the cell's equivalent of power stations. A power station burns fuel to build up steam pressure and uses that pressure to drive a turbine linked to a dynamo. This in turn generates electricity. In mitochondria, the fuel is oxidised and builds up a pressure of hydrogen ions...Poison + water = hydrogen. New microbial genome shows how
...In other words, while other organisms may have the equivalent of a modest mixing bowl to process their supper of carbon monoxide, this species has a veritable food processor, letting it gorge on a hot spring buffet all day. "The findings show the continued value of microbial genome sequencing for exploring th...Infant transplant patients resist infections that kill adult AIDS patients
...althy immune system. Immunologically, they are the equivalent of AIDS patients -- perhaps even more vulnerable to infectious diseases. Yet 10 years post transplant, the patients don't suffer from infections as AIDS patients do. So promising is the work that it recently garnered a $6 million grant from the Nati...Portable cocaine sensor developed at UC Santa Barbara
...r saliva to a degree of a few micromolars. This is equivalent to the concentration of cocaine that would result ...zed swimming pool. That concentration would be the equivalent of detecting three parts per million in blood. Still, this is not yet sensitive enough for use in th...Animal models show that anabolic steroids flip the adolescent brain's switch for aggression
... -- lasted for nearly two weeks of withdrawal, the equivalent of half their adolescence. Eventually, the aggressiveness subsided; by three weeks of withdrawal, all the hamsters greeted intruders with normal, playful defensiveness. Autopsy revealed that the outward aggressiveness correlated with inner changes ...Human prostate grown from embryonic stem cells
...em cells were developed into human prostate tissue equivalent to that found in a young man, in just 12 weeks. Co-first authors of the study, Monash Institute of Medical Research (MIMR) scientists PhD student Prue Cowin and Dr Renea Taylor (also from the Monash Immunology and Stem Cell Laboratories), said the d...Canine cancer vaccine program shows early promise
... treatments in people with cancer. Melanoma, the equivalent of one form of skin cancer in humans, is very aggressive in dogs. It usually manifests itself in or around the mouth or toes. Despite conventional treatment, 75 percent of dogs with oral melanoma will die within one year. But about 40 percent of d...Of mice, men, trees and the global carbon cycle
...with the same total nitrogen content would put out equivalent amounts of carbon dioxide over the same time period. The universal rule linking plant metabolism to nitrogen can also assist efforts to measure the global carbon cycle. Through the process of photosynthesis, plants absorb and store more carbon dioxi...Gene needed for butterfly transformation also key for insects like grasshoppers
...vidence that the nymphal stage in lower insects is equivalent to the pupal, or chrysalis, stage of advanced insects such as butterflies. Metamorphosis evolved in insects about 300 million years ago from ancestors of direct-developing insects such as grasshoppers. Biologists know the broad gene regulates metamo...Fruit fly's beating heart helps identify human heart disease genes
...mutations known to cause disease in humans have an equivalent in the fruit fly. "If there is a mutation in a gene that causes a disease in the fruit fly, then there is a very good chance that there is a corresponding gene in humans," Rockman said. "It is an enormous breakthrough to demonstrate that a human gen...'Executive' monkeys influenced by other executives, not subordinates
...fluences determine who becomes the monkey or human equivalent of Donald Trump, and who becomes a Woody Allen. The researchers -- graduate student Stephen Shepherd, postdoctoral fellow Robert Deaner and Assistant Professor of Neurobiology Michael Platt -- published their findings in the Feb. 21, 2006, issue of ...Growing crops to cope with climate change
... in springtime. We are confident that we will find equivalent genes in other key crops." Professor Julia Goodfellow, BBSRC Chief Executive, said, "Climate change presents a huge challenge for the world. Although every effort must be concentrated on reducing the impact of human activity on the environment, scie...Novel molecular 'signature' marks DNA of embryonic stem cells
...nes poised for later activity. "For genes, this is equivalent to resting one finger on the trigger," said Stuart Schreiber, an author of the Cell paper, the director of the Chemical Biology program at the Broad Institute, and professor at Harvard University. "This approach could be a key strategy for keeping cr...Protein 'nanosprings' most resilient found in nature
...ology at Duke University Medical Center. "It's the equivalent of un-boiling an egg." Marszalek and Bennett are participants in the Duke University Center for Biologically Inspired Materials and Material Systems. The research was supported by Duke University and the National Science Foundation. Ankyrin repeats......he disease's progress. "Knocking out" the gene was equivalent to blocking its corresponding metabolic path, thereby simulating the effect of antibiotics. The analysis demonstrated the following: in the two possible types of salmonella-related illness (diarrhoea and typhoid), the bacteria is surprisingly unaffec...Illinois pig to make history as source of first complete swine genome
...ld a map to know what parts of the pig genome were equivalent to the same parts of the human genome. Now we can take those parts and compare them sequence by sequence." Schook, Beever and Bruce Schatz, interim head of the department of medical information science in the U. of I. College of Medicine at Urbana-C......ivities, and the quality of life in this group was equivalent to that of the general male population of the United States," said Vanessa Howard, R.N., M.S.N., a nurse practitioner for the Immunology service at St. Jude and first author of the paper. "In the past, the majority of patients with XLA died of acute ...