New gene scanning technology marks a major advance in disease research
...protective disease effects, a bit like the medical equivalent of finding a needle in a haystack. 'While this approach is currently at the research level, in the future it could lead to a very personalised genetic profile of a whole range of genes relevant to lifestyle, health and drug prescribing, leading to m...UCLA scientists reveal how Nipah virus infects cells
... kill up to 70 percent of patients ?a danger level equivalent to the Ebola virus. To infect a cell, viruses must bind to a viral-specific receptor on the cell's surface in order to penetrate it. Lee's team identified a cell receptor called Ephrin-B2 as the key used by the Nipah virus to unlock the cells. Loca...Scientists find a maturity gene in fly
...al for studying genetics." Thummel says the human equivalent of the fruit fly DHR4 gene probably does not work the same way in people as it does in flies. "But things we can study in detail in the fly, like the role of DHR4 in maturation, will provide new directions for understanding poorly defined processes i...MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools
...al for studying genetics." Thummel says the human equivalent of the fruit fly DHR4 gene probably does not work the same way in people as it does in flies. "But things we can study in detail in the fly, like the role of DHR4 in maturation, will provide new directions for understanding poorly defined processes i...A New Era Of Hope For Neglected Diseases
... around 3m people a year and cause the loss of the equivalent of 92m years' of healthy life, there are now over 60 drug research projects underway. In the PLoS Medicine analysis, which is based upon a 100-page report financed by the Wellcome Trust, Mary Moran of the London School of Economics found that around...U-M scientists discover identifying markers for primitive blood-forming stem cells
...igan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood. By reading the bar code, scientists can separa...Discovery that bacterium is phosphate gourmet key clue to what makes it most social of bacteria
...phisticated consumer of phosphates - the bacterial equivalent of a gourmet diner. That the 3 pathways act in concert probably enables the organism to find phosphates in different chemical states or environmental conditions, or even to exploit the phosphates found in other M. xanthus cells or those of potentia...Gene therapy works in mice to prevent blindness that strikes boys
...development, the condition in the mice was roughly equivalent to retinoschisis in a 10-year-old boy. Six months later, researchers looked at the interior of the eyes with a laser ophthalmoscope and found cyst formation was clearly evident in the untreated eyes, but the treated eyes appeared healthy. The eye's ...Restaurant seafood prices since 1850s help plot marine harvests through history
...e of a wild canvasback duck meal rose from today's equivalent of $20 in the 1860s to $100 in 1910 as stocks coll...flation-adjusted chart shows prices flat at a 2004 equivalent of about $7.00 until the late 1930's and a second jump in inflation-adjusted prices in the late 1950...Living anti-HIV gel shows early promise
...e, trials on monkeys exposed to HIV or the primate equivalent (SIV) will have to be successful before the bacteria can be tested in people. "It is a fascinating concept," says Harold Kessler, associate director of the Infectious Diseases Section at Rush University Medical Center in Chicago, United States. "Obvi...Fresh water affected by salt from deicing roads
...increase in waterways to as high as 5 g/l which is equivalent to 25% of seawater concentrations. Dr. Kaushal of the University of Maryland Center for Environmental Science Appalachian Laboratory said, "There is a direct connection between the rate of construction of new roadways and parking lots and th...Scientists discover the molecular switch for nerve cells' insulating jelly rolls
...n thick layers of myelin, producing the biological equivalent of a jelly roll. Using a sophisticated system for growing nerve cells in laboratory dishes, the team identified a gene called neuregulin as the myelin signal. This signal directs Schwann cells, the nervous system's cellular architects, to build elab...Fish evolve a longer lifespan by evolving a longer reproductive period, researchers find
...? "We were exploring whether or not fish have the equivalent of mammalian menopause," Reznick said. "We found that 60 percent of the fish had a significant post-reproductive lifespan, indicating that, yes, fish do have menopause. Indeed, their patterns of growing old are similar to those of mammals." The rese...Study reveals genomics of inflammation from severe injury
...these issues, scientists have produced the genomic equivalent of a time-lapse movie, tracking the activity of thousands of genes through the course of body-wide inflammation. The research appears in the August 31 advanced online issue of Nature. "This work represents a major step in understanding inflammation ...Health benefits of a Christmas brandy
.... He said a shot (30mls) of brandy would give the equivalent antioxidant potential to the daily recommended intake of vitamin C. "The antioxidants only make up only a small percentage of substances found in brandy, but they are a very important part of the mix. "So when you are enjoying a slice of brandy-inf...Study Unlocks Insects?Secret for Love in the Dark
...these issues, scientists have produced the genomic equivalent of a time-lapse movie, tracking the activity of thousands of genes through the course of body-wide inflammation. The research appears in the August 31 advanced online issue of Nature. "This work represents a major step in understanding inflammation ...DNA self-assembly used to mass-produce patterned nanostructures
... The structure of the tiles created the molecular equivalent of puzzle pieces that would self-assemble only in a specific arrangement when mixed together, with the DNA loop loaded with a desired "cargo" molecule that would form the structure the researchers wished to create. In one experiment, the scientists s...Researchers show how air pollution can cause heart disease
...mount is within the range of annual EPA limits and equivalent to air quality in urban areas such as New York City. The researchers then conducted an array of tests to measure whether the PM2.5 exposure had any impact on the mice's cardiovascular health. Overall, mice who breathed polluted air fared worse than...Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace
...'s antennal lobe (AL), considered the invertebrate equivalent of the brain's olfactory bulb. Team member Marcel Weidert placed fluorescent probes within different glomeruli, and imaged their activity using dyes sensitive to the opening and closing of calcium channels on neurons. The scientists created an imagin......preserved cognitive abilities are not biologically equivalent to young rats in some of the basic machinery that neurons use to encode and store information in the brain," said Gallagher, who collaborated with Alfredo Kirkwood and Sun Seek Min of Johns Hopkins' Krieger Mind/Brain Institute and Hey-Kyoung Lee, no...