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Tag: "equivalent" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...ene aptly named KiSS-1. The couple ?a biochemical equivalent to Adam and Eve ?makes its sudden appearance in a region of the brain called the hypothalamus just as puberty begins, according to a study published in this week's online edition of the Proceedings of the National Academy of Sciences (PNAS). Until...

Man and mouse share genome structures

... and mouse genomes, finding similar patterns along equivalent chromosomal regions, even where the underlying DNA sequences are different. Bernstein and Schreiber began to develop the analytical techniques several years earlier, working with the smaller yeast genome. To investigate the much larger human genome,...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

... levels had spiked abnormally, to 500 mg/dl -- the equivalent of serious, full-blown diabetes in humans," Dr. Patti said. In type 1 diabetes, the pancreas cannot make the hormone insulin at all; about 1 million Americans must control this form by taking insulin injections. In type 2 -- a disorder affecting an ...

Mouse brain tumors mimic those in human genetic disorder

...hs of age. After thattime-period, which is roughly equivalent to teenage years in humans,the cells slowed down to the same growth speed as astrocytes in controlmice."The fact that cell growth is dramatically reduced after a few monthsin mice and after a few years in humans tells us there may be growthsignals th...

Jumping gene helps explain immune system's abilities

...leftover ones, creating aunique gene (the cellular equivalent of the diner's meal). Snipping outdifferent sections will lead to a different gene, carrying instructionsfor a different protein that will recognize a different antigen, and onand on.This a la carte process, known as V(D)J recombination, is similar t...

UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections

...leftover ones, creating aunique gene (the cellular equivalent of the diner's meal). Snipping outdifferent sections will lead to a different gene, carrying instructionsfor a different protein that will recognize a different antigen, and onand on.This a la carte process, known as V(D)J recombination, is similar t...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

...leftover ones, creating aunique gene (the cellular equivalent of the diner's meal). Snipping outdifferent sections will lead to a different gene, carrying instructionsfor a different protein that will recognize a different antigen, and onand on.This a la carte process, known as V(D)J recombination, is similar t...

Gene sequencing explains bioremediation 'bug'

...leftover ones, creating aunique gene (the cellular equivalent of the diner's meal). Snipping outdifferent sections will lead to a different gene, carrying instructionsfor a different protein that will recognize a different antigen, and onand on.This a la carte process, known as V(D)J recombination, is similar t...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...del with an inactivating mutation within the mouse equivalent of the APC gene displays very similar pathology as seen in human colon cancers and develop tumor growths called polyps in their colons, eventually leading to death. Inactivating the APC gene was found, as in human cells, to cause the accumulation of ...

Wisconsin researchers identify sleep gene

...evertheless, Shaker's main job in flies-and in its equivalent in humans--is to control the excitability of cell membranes. Genetic analysis of the mns flies, conducted by Daniel Bushey, a post-doctoral fellow working with the Tononi team, revealed that their Shaker genes contained a single amino-acid mutation....

A frog's life is food for thought

...had eaten regularly. "They can take massive meals equivalent to 50 percent of their body mass and maximise their digestive capability from the outset," Ms Cramp said. Little is known about the effects of prolonged food deprivation on the gut of animals that go without food for long periods. Ms Cramp's study i...

Biodiversity hotspots identify conservation priorities

...g just 2.3 percent of the Earth's surface (roughly equivalent to the combined areas of the five largest U.S. sta...vered 15.7 percent of the Earth's surface, an area equivalent in size to Russia and Australia combined. The new analysis shows that an estimated 50 percent of all...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...cent state, waiting in the tick's midgut, which is equivalent to our digestive system." When blood enters the tick gut, Dr. Norgard said it appears that changes in temperature and acidity signal the bacteria that the nutrient is present, triggering the bacteria to replicate in large numbers and migrate to the ...

To control germs, scientists deploy tiny agents provocateurs

...ogous to one man, biofilms would be the "bacterial equivalent of mob mentality," says Blackwell. In the realm of health, biofilms are at the root of growing numbers of tenacious, and sometimes fatal, hospital infections, says Blackwell. Indeed, a U.S. National Institutes of Health study last year reported that...

Migratory songbirds have a specialized night-vision brain area

...hey first accustomed the birds to the illumination equivalent of moonlight. They waited until the birds were sitting quietly to eliminate brain activity from movement. The researchers then quickly preserved the birds' brains, and in Jarvis's laboratory analyzed the brain structures for the active expression of ...

Red delicious, Northern Spy apples have most antioxidants, chemists find

...posed to a known carcinogen and then fed the human equivalent of one, three or six apples a day respectively over 24 weeks were up to 44 percent less likely to develop breast tumors. That study was published in the April 6, 2005, issue of the Journal of Agricultural and Food Chemistry. ...

Of mice and men's (and women's) contraceptives

...on understanding this mechanism." A similar human equivalent of MSY2, Contrin, has been identified by the research group and their studies indicate it is also a germ cell-specific protein. Using MSY2 as a mouse model, Hecht and colleagues hope that Contrin can be developed as a new non-hormonal target for huma...

15-year hunt finds cause of pseudothalidomide syndrome

...ions in people with the syndrome. Knocking out the equivalent gene in yeast and fruit flies led to the same chromosome problems, says Gordillo. "Comparative genomics didn't really exist even five years ago," says Jabs. "Techniques to genetically engineer yeast, fruit flies and even mice have dramatically impro...

Future diabetes drugs may target new protein interaction

...als for the first time. In bacteria and yeast, the equivalent of sirtuin1 is already known to help slow processes linked to cellular aging when food is scarce, an effect that extends the single-celled organism's lifespan. "We now know that sirtuin1 is directly involved in the response to calorie restriction in...

PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information

...als for the first time. In bacteria and yeast, the equivalent of sirtuin1 is already known to help slow processes linked to cellular aging when food is scarce, an effect that extends the single-celled organism's lifespan. "We now know that sirtuin1 is directly involved in the response to calorie restriction in...

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