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Tag: "epilepsy" at biology news

Research on Worms Yields Clues on Aging

...akingprogress; in worms. Researchers found that an epilepsy drug used inhumans had the unexpected effect of pr... in St. Louis. When exposed to drugs used to treat epilepsy inhumans, worms lived longer and retained youthful functions longer thannormal.Because the drugs aff...

Gene variations explain drug dose required to control seizures

...g which variants of particular genes patients with epilepsy carry might enable doctors to better predict the d...a partnership, aimed at tailoring the treatment of epilepsy to patients' genetic makeup, between the Department of Clinical and Experimental Epilepsy at the Uni...

UCSD research reveals mechanism involved with type of fatal epilepsy

...ve found that Lafora disease, an inherited form of epilepsy that results in death by the age of 30, can be caused by mutations in a gene that regulates the concentration of the protein laforin. These findings are reported in the current issue of Proceedings of the National Academy of Sciences (PNAS). Lafora ...

Brain May Be Less Plastic Than Hoped

...e for injuries is well known. Children with severe epilepsy who lose an entire hemisphere during surgery can regain motor control on the affected side of their body and go on to develop normal language skills. But in adults, the case for brain plasticity has been less clear. A series of studies in the 1980s ...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

... gene therapy for treating Parkinson's disease and epilepsy and its core technology, which it refers to as "NLX," is currently being tested in a Company-sponsored Phase I human clinical trial to treat Parkinson's disease. ...

Huntington's cure in flies lays groundwork for broader treatment approaches

...cting research dollars to the continued search for epilepsy genes, Yin believes funding agencies should now consider investing in the search for these "superhighways" of gene convergence. That search might be long and tedious, he adds, but it's most certainly worth a shot. "I think the history of scientific ...

New battery technology helps stimulate nerves

...tical connections in, for example, Parkinson's and epilepsy patients. Designed to be extraordinarily reliable ...nervous system wiring at the heart of Parkinson's, epilepsy and incontinence. "The idea is that whenever you have a broken nerve connection, you can supply the...

You will remember this

...r since the 1960s, are used in hospitals to detect epilepsy in people and are an important tool to show not just what bits of the brain are lighting up but also what triggers it to light up and when. In this test, the important thing was to find out whether brain activity before an event has an impact on me...

Study ties 'new' cell-death mechanism to developmental and degenerative brain disorders

... to eye movement abnormalities, cognitive decline, epilepsy and other significant deficits. Twenty-seven specific locations on human chromosomes have been identified for involvement in the development of ataxias, and 10 causative genes or mutations have been determined. The gene and mutations in this study a...

Mechanism for memory revealed in neurons of electric fish

...erstand memory formation and neural disorders like epilepsy in humans. Dr. Harold Zakon, Dr. Jörg Oestreich and colleagues show that when electric fish zap each other in dark waters, their neurons store a memory of the sizzling communiqué by turning on special cell membrane channels. The channels give the f...

'Word-vision' brain area confirmed

... as well. Now, a patient whose surgery to relieve epilepsy specifically disrupted the VWFA has given researchers, led by Laurent Cohen of the Hôpital de la Salpêtrière, an opportunity to demonstrate that the region does indeed play a causal role in the ability to recognize words. The researchers reported in...

Oops! Researchers publish new findings on the brain's response to costly mistakes

...techniques used to study the brains of people with epilepsy or sleep problems, but the electrical signal from the brain is processed in a different way. In prior studies, Gehring and his colleagues observed a distinct brain electrical response to errors, dubbing it ERN for "error-related negativity." Using E...

Molecular mechanism may explain how fevers spark seizures

...'ve also been something of an enigma, he said. The epilepsy research community has struggled to understand how...seizures when she was working as a neurologist and epilepsy specialist in her native China. "I was always impressed by how quickly fevers can trigger convulsi...

Blood flow in brain takes a twist, affecting views of Alzheimer's

...publications fingering astrocytes in diseases like epilepsy and spinal cord injury. "In a disease like Alzheimer's, for instance, perhaps it's the astrocytes themselves that are damaged first," she said. "It may be that for whatever reason, astrocytes are not doing their job properly, and then blood flow dec...

UCLA paper examines how one disease may prevent another

...he ketogenic diet is still used today for cases of epilepsy resistant to medication. During the 1994 winter of starvation when bread supplies to the children's hospital were interrupted at The Hague, young patients with celiac disease, a digestive disease that damages the small intestine and interferes with...

Convergent evolution of molecules in electric fish

...nel proteins can cause serious muscular disorders, epilepsy and heart problems in humans and other vertebrates. But fish have two copies of many of their genes, and Zakon found that the duplicate sodium channel gene could mutate and evolve without harming the fish. "The spare gene gave [the electric fis...

Autistic brain has fewer neurons for processing emotion

...es, the sample excluded brains of individuals with epilepsy or similar disorders associated with cell loss in the amygdala. Paradoxically, past research using magnetic resonance imaging with children has shown that the amygdala in young males with autism is abnormally large in volume due to precocious matu...

Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent

...terest in how the brain works has led him to study epilepsy and Alzheimer's disease. People who suffer Alzheim...ptic rats In this study, the researchers induced epilepsy by injecting anesthetized rats with pilocarpine, a drug that excites the brain's neurons and activat...

'Smart' genetic therapy helps the body to heal itself

...identified a drug ?valproate, used successfully in epilepsy treatment for decades ?that is able to increase SM...tissues such as cultured brain slices derived from epilepsy patients after surgery, as well as motor neuron cultures derived from rat embryos. "The next step w...

Test reveals effectiveness of potential Huntington's disease drugs

...amotrigine, both glutamate inhibitors, are used in epilepsy treatment and as a mood stabilizer, respectively. These three compounds did not significantly protect the cultured cells. However, a drug called memantine, which is used to treat Alzheimer's disease, and riluzole, used in amyotrophic lateral scler...

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