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Tag: "entry" at biology news

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...iously unknown onethat may also be relevant to the entry of other small molecules intocells. In addition, the JBC study showed how Neu5Gc attached to dietaryproteins from animals could be incorporated into cells lining thestomach and colon, organs where consumption of red meat has beenassociated with risk ...

Scientists Replicate Hepatitis C Virus in Laboratory

...he beginning stages of the viral life cycle ?viral entry into host cells and viral activity in the host cell before replication. “With this cell-based system, we can screen compounds with a cell-based assay to look for inhibitors of virus replication,?says Liang. “We can also apply this technique to devel...

Research advances quest for HIV-1 vaccine

...protein is thought to play a key role in mediating entry of HIV-1 into human cells. A research group led by Drs. Dennis R. Burton and Ian A. Wilson from The Scripps Research Institute in La Jolla, California performed a study examining the detailed molecular structure of the complex formed when 4E10 binds...

Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

...isible Bytes Software Inc.).GeneLinker Gold is the entry level product that is well suited toresearchers just entering the area of genomics or proteomics research,while GeneLinker Platinum offers powerful feature detection, committeesof neural networks, committees of SVMs and committees of Bayesianclassifi...

The secret lives of whales

...ave taken heed, and instituted steps to reduce the entry of contaminants to the oceans. ...

International trial of two microbicides begins

...l testing. It is believed to act by inhibiting the entry of HIV and other pathogens into body cells. BufferGel, a product of ReProtect, Inc., Baltimore, MD, boosts the natural acidity of the vagina in the presence of seminal fluid that neutralizes the vaginal environment. An acidic environment inactivates ...

MetaChip provides quick, efficient toxicity screening of potential drugs

...l testing. It is believed to act by inhibiting the entry of HIV and other pathogens into body cells. BufferGel, a product of ReProtect, Inc., Baltimore, MD, boosts the natural acidity of the vagina in the presence of seminal fluid that neutralizes the vaginal environment. An acidic environment inactivates ...

HIV-1 spread through six transmission lines in the UK

...oes against the prevailing belief that one initial entry of HIV-1 was responsible for the spread of the epidemic. “Since 1990 there have been important changes in Britain's social attitudes and awareness of HIV-1 and AIDS. Despite a very recent increase in high-risk behaviour among men having sex with men...

Buying Time Through Hibernation on Demand

...ds that won't heal. A wound to the skin allows the entry of oxygen, which initiates cell death. In healthy people, cell death subsides when a clot forms, which allows the healing process to begin. Exposing a diabetic's clot-resistant wound to an oxygen-free environment would speed the healing process. Whi...

U-M team recovers ancient whale in Egyptian desert

...ds that won't heal. A wound to the skin allows the entry of oxygen, which initiates cell death. In healthy people, cell death subsides when a clot forms, which allows the healing process to begin. Exposing a diabetic's clot-resistant wound to an oxygen-free environment would speed the healing process. Whi...

Biologists discover why 10% of Europeans are safe from HIV

...viral, haemorrhagic fever that used the CCR5 as an entry port into the immune system. Using computer modeling, they demonstrated how this disease provided the selection pressure that forced up the frequency of the mutation from 1 in 20,000 at the time of the Black Death to values today of 1 in 10. Lethal,...

First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes

...viral, haemorrhagic fever that used the CCR5 as an entry port into the immune system. Using computer modeling, they demonstrated how this disease provided the selection pressure that forced up the frequency of the mutation from 1 in 20,000 at the time of the Black Death to values today of 1 in 10. Lethal,...

NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells

...sequence of events by which insulin stimulates the entry of glucose into fat cells. The study, appearing in the May 9 Journal of Cell Biology, was conducted by researchers from the National Institute of Child Health and Human Development and the National Institute of Diabetes and Digestive and Kidney Dise...

NIAID begins clinical trial of West Nile virus vaccine

...uction of antibodies to block the WNV from gaining entry into cells, and killer T cells, which kill WNV-infected cells outright. "The DNA vaccine's exploitation of both cellular and antibody immunity offers a potentially potent defense against West Nile virus," says Barney Graham, M.D., Ph.D., chief of th...

Researchers develop assay that could be applied to drug screening

...y several viruses, including rabies, as a means of entry into healthy cells. The researchers led by David Zenisek, assistant professor in the Department of Cellular and Molecular Physiology at Yale School of Medicine, used live cell imaging and a novel fluorescence assay to visualize the formation of clat...

Critical step traced in anthrax infection

...l (HMS) have revealed details of a key step in the entry of anthrax toxin into human cells. The work, which grew out of an ongoing effort to produce a better anthrax therapeutic, shows that the protective antigen component of the bacterial toxin plays an active role in transferring the other two components...

When it comes to cell entry, being average has its advantages

When it comes to gaining entry into cells, size matters. A team from Brown Univer...ication, say ?knowing an optimal particle size for entry is also helpful. "With nanotubes, we may be able to manufacture ones of a certain size to minimize ...

Achilles heel of the herpes virus possibly found

...as been shown to use a cellular fusion protein for entry into cells." She explains that the search for the...es for virus binding to cells make deciphering the entry process a difficult problem to solve. The gene that encodes B5 had in fact been sequenced, but not ...

Study shows how retinoic acid enters a cell's nucleus

...ting vitamin A derivative retinoic acid (RA) gains entry into a cell's nucleus. When vitamin A enters a cell's cytoplasm (the portion that lies between the outer membrane and the nucleus), it can be converted to RA, a member of a group of compounds that enter a cell's nucleus and play a role in triggering...

Orientation and the egg

... contrast to those who feel that the site of sperm entry determines the orientation of the future body axes. "It would now make sense to base our future experiments on the premise that the mammalian egg neither has nor requires predetermination for successful development," explains Dr. Hiiragi. ...

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