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Tag: "enters" at biology news

Tool developed to silence genes in specific tissues using RNAi

...many life forms to identify viral RNA, which often enters a cell as a double strand. The organism's own RNA, however, leaves the nucleus of cells (where it was produced by DNA) as a single strand, to be decoded by ribosomes into the proteins that perform all the work of the cell. RNAi, therefore, recognizes...

Scientists reveal how deadly toxin hijacks cells

...ngerous threat as a biological weapon. The toxin enters neurons by binding to nerve endings and preventing the release of crucial chemical messengers, known as neurotransmitters, that communicate with muscles. When enough nerve endings are invaded, botox can lead to paralysis and death. By capitalizing o...

Research details how a virus hijacks cell signals to cause infection

...stine, called epithelial cells. Just how the virus enters those cells has been puzzling to scientists. Dr. Bergelson previously discovered a cell receptor called the coxsackievirus and adenovirus receptor (CAR) to which the virus attaches itself. However, the CAR remains below the surface of epithelial cell...

Study shows that cells have a natural defense against HIV

... DNA can also destroy the DNA made by HIV after it enters a human cell. This HIV DNA is essential for the virus to survive and reproduce. The study was led by researchers at The Ohio State University Comprehensive Cancer Center ?Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSU...

How sperm crack the whip

...acing how calcium triggers hyperactivation once it enters the cell. Such studies will enable exploration of sperm machinery from tail to head ?analyzing processes ranging from tail motility to the mechanism by which the sperm head delivers its genetic payload to the egg, he said. Such research could yield...

Scientists identify molecular structure of key viral protein

...different shapes, one before the virus attacks and enters a cell and one after. The parainfluenza virus 5 fusion protein is one of these. It is the change of the fusion protein from the initial metastable state to the post-virus entry state that drives the fusion of viral and cellular membranes, permitting ...

Unraveling the viral mechanism

... also identified a protein "hub" through which DNA enters and exits the virus. "It's like a garden hose, in some ways," said Chiu. "You extend it. If you put it away in a heap, then you have trouble using it again. But if you coil the hose orderly, then it is easy to use again. I think the virus does the s...

APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal

...s inside a mouse lymph node when a foreign microbe enters the body. The videos were made possible by recent technological advances together with techniques the von Andrian lab developed. *Henry Pickering Bowditch Award Lecture: "Migrants on a single-minded mission: How T cells find their antigen," 5:45 p.m...

Iron critical to ocean productivity, carbon uptake

...an come from the deep or from the air, but it also enters the ocean through dust deposited by the wind. Windstorms blowing sand and dust off large deserts are a major source of iron for the world's oceans. "It's like dumping a load of Geritol or some other iron supplement into the water." Three large area...

Honey helps problem wounds

...leukaemia have a weakened immune system. If a germ enters their bloodstream via a wound, the result may be a fatal case of blood poisoning. For several years now Bonn paediatricians have been pioneering the use in Germany of medihoney in treating wounds. Medihoney bears the CE seal for medical products; it...

Radioactive scorpion venom for fighting cancer

...tive substance called iodine-131 (I-131). When it enters the bloodstream, the compound attaches to the glioma cells, then the I-131 releases radiation that kills the cell. This compound has enabled an experimental treatment for high-grade gliomas, found in 17,000 people in the US every year and usually ...

Many cleaners, air fresheners may pose health risks when used indoors

...compounds. (The primary constituent of smog, ozone enters the indoor environment from infiltration of outdoor air, but is also produced indoors by some office machines such as copiers or printers, and by some devices marketed as "air purifiers" that purposely emit ozone into the indoor environment.) The re...

Impressive new Impact Factors for BioMed Central's open-access journals

...evelopmental biology field. BMC Structural Biology enters the Biophysics category at number eight, with an Impact Factor of 5.00. BMC Evolutionary Biology's Impact Factor of 4.45 is the 6th most highly cited journal in the evolutionary biology category. BMC Biotechnology now has an Impact Factor of 3.05, BM...

Dolphins at risk

...y starts and marine work should cease if a dolphin enters the work area. Other innovative ideas include creating an air bubble curtain and creating a ramped warning signal to give dolphins time to leave the area before work commences. Dr David also calls for further research into the reactions of marine m...

South Pacific plant may be missing link in evolution of flowering plants

...y starts and marine work should cease if a dolphin enters the work area. Other innovative ideas include creating an air bubble curtain and creating a ramped warning signal to give dolphins time to leave the area before work commences. Dr David also calls for further research into the reactions of marine m...

New understanding of parasite cell structures may provide treatments for serious tropical diseases

...s from the mid-gut to the salivary glands where it enters the human bloodstream when the fly bites. "We found that putting these cells under stress similar to that initially encountered by the trypanosome inside the fly caused the parasites to cleave free GPIs," said Mensa-Wilmot, "and that gives us import...

Interfering RNA silences genes in 'slippery' immune cells

...netic code that produces a specific siRNA after it enters a nucleus. The researchers encased the DNA within an siRNA expression cassette (SEC), an inexpensive, quickly synthesized product that carries genetic sequences to regulate the gene activity that yields an siRNA. After the researchers tested a variet...

'Smart' genetic therapy helps the body to heal itself

... on valproate, which belongs to the HDAC class and enters the brain ", said Professor Pujol. The scientists tested valproate and found that it could indeed induce ALDR gene expression in human cell lines and rat and human brain slices. "We then treated 8 X-ALD patients with oral valproate over 6 months",...

Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check

...merase molecules ?careless ones ?to the clamp. p53 enters the picture when it is alerted to the damage and causes p21 to be created. The p21 then acts as a sort of facilitator, helping to fasten the proper ubiquitin in place and clearing stalled DNA polymerase out of the way so its replacement can get to wo...

Targeted virus compels cancer cells to eat themselves

...umors, as a target,'' Kondo says. ''Once the virus enters the cell, it needs telomerase to replicate. Normal brain tissue does not have telomerase, so this virus replicates only in cancer cells.'' Other cancers are telomerase-positive, and the researchers showed in lab experiments that the virus kills huma...

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