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Tag: "enters" at biology news

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

... thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude Structural Biology. Kriwacki is ...

New comparative toxicogenomics database

... thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude Structural Biology. Kriwacki is ...

Scientists reveal molecular secrets of the malaria parasite

...lates proteins that are switched on as theparasite enters the mosquito.Hall's group identified the gene regulation by comparing the genesexpressed in the sexual stage transcriptome with the proteomes of boththe sexual stage and a developmental stage in the mosquito. Severalgenes were identified for which tr...

Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

...ed a replication-defective adenovirus that readily enters cells but doesn't reproduce itself. Ahrens injected the vector carrying the MRI reporter gene into brains of living mice and imaged the MRI reporter expression periodically for over a month in the same cohort of animals. The research showed no overt ...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

...he metabolic byproducts that retain the carbon-11) enters and clears the various organs. The radiotracer decays and completely clears from the animal's body in about two hours. After the procedure, the animals were returned to their social colony to deliver their offspring. The combined images show that co...

Researchers discover molecular mechanism that desensitizes us to cold

... of cold. When the receptor is stimulated, calcium enters the cell and stimulates the breakdown of PIP2. When PIP2 is broken down, the receptor becomes inactive, thus ending the sensation or desensitizing the cell to the cold stimulus. "This finding provides critical information to help us understand how w...

Chemists identify immune system mechanism for methamphetamine binges

...hemical reactions that occur with the drug when it enters the bloodstream, the researchers showed that methamphetamine reacts with glucose and proteins to form a larger-size "glycated" product. This product is then recognized by immune system components, stimulating the production of antibodies to the drug....

Researchers identify protein crucial for survival of Lyme-disease bacterium

...s equivalent to our digestive system." When blood enters the tick gut, Dr. Norgard said it appears that changes in temperature and acidity signal the bacteria that the nutrient is present, triggering the bacteria to replicate in large numbers and migrate to the tick's salivary glands, where they are transm...

NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells

.... GLUT 4, contained in the vesicles?membrane, then enters the cell membrane, where it ferries glucose into the cell. The researchers made their observations using a technique known as total internal reflector florescent microscopy. The technique consists of aiming a laser beam at an angle at the glass cove...

New strategies to reduce hospital-aquired infections

...ing formation of new biofilm colonies. When water enters a hospital room from a faucet or shower, tiny water droplets containing the biofilm contaminants separate from the main water stream and spread by air currents in all directions. Some of these contaminants are inhaled as aerosols (tiny water droplets...

Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST)

...ing formation of new biofilm colonies. When water enters a hospital room from a faucet or shower, tiny water droplets containing the biofilm contaminants separate from the main water stream and spread by air currents in all directions. Some of these contaminants are inhaled as aerosols (tiny water droplets...

Virologists make major step towards understanding the process of HIV infection

...tists to observe the behavior of the virus when it enters a host cell, during replication and when it leaves a cell. This is a major step towards understanding the process of HIV infection. Modern imaging technologies facilitate real-time observation of virus-cell interactions. Many of these investigation ...

New Species of Coral Discovered Off Southern California

...tists to observe the behavior of the virus when it enters a host cell, during replication and when it leaves a cell. This is a major step towards understanding the process of HIV infection. Modern imaging technologies facilitate real-time observation of virus-cell interactions. Many of these investigation ...

Random gene expression may drive HIV into hiding

...the infected cells. In this model, after HIV's RNA enters a host cell, it is copied into DNA, and then a little bit of Tat is made before the virus integrates into the host genome. At this point, Tat must be chemically modified before it can encourage transcription of more HIV, and random thermal fluctuati...

Open Access journals get impressive impact factors

...and is supported by a major society. BMC Genomics enters the Journal Citation Report with a respectable 3.25. This puts it in the top third of the genetics titles, and the top 20% of biotechnology journals. BMC Molecular Biology has an impact factor of 3.12, and BMC Musculoskeletal Disorders an impact fact...

'Bionic' arm gives amputee sense of touch

...and is supported by a major society. BMC Genomics enters the Journal Citation Report with a respectable 3.25. This puts it in the top third of the genetics titles, and the top 20% of biotechnology journals. BMC Molecular Biology has an impact factor of 3.12, and BMC Musculoskeletal Disorders an impact fact...

Achilles heel of the herpes virus possibly found

...ns that the search for the mechanisms by which HSV enters cells has been hindered by the fact that the virus is very good at entering so many kinds of cells. The many possibilities for virus binding to cells make deciphering the entry process a difficult problem to solve. The gene that encodes B5 had in fa...

Virginia Tech group adds tools to DNA-targeted anti-cancer drugs

...ll allow us to see such things as how the assembly enters cells and how much of the drug reaches the DNA," Brewer said. "It is a common practice in the medical field to use luminescent dyes to study cells, so pathology labs will have the equipment needed to monitor drug delivery. Brewer is giving her invit...

Bad aftertaste? New sensory on/off switch may 'cure' bane of artificial sweetener search

...ll allow us to see such things as how the assembly enters cells and how much of the drug reaches the DNA," Brewer said. "It is a common practice in the medical field to use luminescent dyes to study cells, so pathology labs will have the equipment needed to monitor drug delivery. Brewer is giving her invit...

Anthrax inhibitors identified by Burnham team

...s sufficiently concentrated in the bloodstream. LF enters cells and inactivates a human protein called "mitogen-activated protein kinase", or "MAPKK", disrupting the normal signaling pathways of the cell and inducing cell-death. Using a fragment-based approach based on assays conducted with highly sensitiv...

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