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Tag: "enter" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

... yet when this experimental molecule will actually enter the consumer market, but any useful application is likely to take five to ten years, the researcher estimates. Administration of the molecule for drug delivery could be by mouth or by injection, he adds. There are hurdles to overcome. The current ve...

DNA Molecules Used To Assemble Nanoparticles

...y targeted to cancer cells and are small enough to enter a diseased cell, either killing it from within or sending out a signal to identify it. But making the particles is notoriously difficult and time-consuming. The nanoparticle system used by Baker's lab is based on dendrimers, star-like synthetic poly...

UAB scientists discover the origin of a mysterious physical force

...tanding how substances penetrate cell membranes to enter cells. These drugs are often proteins designed to prevent or strengthen the action of other substances. In these cases, accurately identifying the protein folding is essential, since the form these proteins take on when they fold influences how effec...

Fox Chase Cancer Center scientists identify immune-system mutation

...w) generate antibodies against foreign agents that enter the body. Other T cells are known as killer cells because they attack foreign invaders more directly. "The maturation of T cells involves key branch points at which cells choose one of two different pathways, going on to become helper cells or kille...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...ggering other changes that allow the AIDS virus to enter and infect cells. Their findings, published in the...s membrane. This fusion of membranes allows HIV to enter the cell and begin replicating. The structure of gp120 after it binds to the CD4 receptor and chang...

Plants respond similarly to signals from friends, enemies

...proach a plant and communicate with it in order to enter a partnership. The friend wants to trade nitrogen for food. The foe is a parasite that wants to burrow in and harm the plant. In a new finding published in Proceedings of the National Academy of Sciences, researchers at North Carolina State Universi...

Computers to be used to find blueprint for new influenza drug

... acid, from the throat cell, allowing the virus to enter the cell and reproduce. The new drug would be chemically similar to the sialic acid, but would act to inhibit the sialidase. This would hinder the virus from entering the cells, and from leaving them should they gain entry, thereby controlling the s...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...a that are taken up by macrophages in the lung and enter a dormant state ?these are the hardest to attack with drugs." ...

The secret lives of whales

...w whales move away or go quiet as human activities enter an area. Every decade the amount of noise is doubling. “Whales have very traditional feeding grounds and their migratory routes along coastlines have become incredibly noisy, urbanized habitats,?Clark explains. “Acoustic smog is shrinking their world...

Taking Aim With Nanoparticle PEBBLEs

...ncer cells and disrupting their DNA, PEBBLEs never enter the cells they target. Instead, they attach to the outside of the targeted cell and shoot reactive oxygen species into it, setting off "an avalanche of damage," said Kopelman. By staying outside the cell, PEBBLEs avoid a problem that thwarts many che...

Open microfluidic and nanofluidic systems

...uid, one observes that the liquid often refuses to enter the channels. In fact, as shown in the new PNAS study, liquids at surface channels can attain a large variety of different wetting morphologies including localized droplets, extended filaments, and thin wedges at the lower channel corners. Examples f...

Agilent Technologies releases automated literature search tool for biology researchers

...th the Agilent Literature Search tool, researchers enter the names of all genes of interest, along with keywords that describe the types of relationships being looked for. The plug-in searches accessible databases and generates a computational representation of gene/protein associations grouped into a netw...

Scientists discover that host cell lipids facilitate bacterial movement

... cells and are ingested by them. The bacteria then enter the new cell and begin the cycle anew. Essentially Listeria takes over or hijacks the host cell's actin cytoskeleton to move within cells, and to spread from cell to cell." In most cells, two membrane lipids, PIP2 and PIP3, are associated with the f...

Antibiotic might fight HIV-induced neurological problems

...on-fighting cells known as macrophages, which then enter the brain. The influx of these cells contributes to swelling and inflammation known as encephalitis. The other protein, p38, helps trigger a series of events that result in a cell's programmed death, called apoptosis. Only one of the five treated mo...

Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer

... a partner on their target cell, fuse membranes to enter the target cell and then take over the cellular ma... cells and using it as a homing device to seek and enter cancer cells. The measles virus became the focus of this vision several years ago when the surprisi...

How the environment could be damaging men's reproductive health

...nsume large quantities of local fatty fish." POPs enter the environment in a number of ways. Tarmo Tiido, co-author and PhD student at the Fertility Centre, said: "The sources of contamination for POPs are closely related to human activities such as domestic and industrial discharge, automobile exhausts, ...

Gene therapy promising for growing tooth-supporting bone

...ffects turned off, harnesses the virus' ability to enter into cells and use their genetic machinery. Once inside the cell, the viruses help BMP-7 genes get where they need to be in the host's cells to boost bone production. Gene expression producing BMP-7 proteins peaked after a week. Giannobile said that...

Buying Time Through Hibernation on Demand

...causes the organism to shut down metabolically and enter a hibernation-like state. In each case, upon re-exposure to normal room air, the organisms quickly regained normal function and metabolic activity with no long-term negative effects. If Roth and colleagues are able to replicate these findings in lar...

U-M team recovers ancient whale in Egyptian desert

...causes the organism to shut down metabolically and enter a hibernation-like state. In each case, upon re-exposure to normal room air, the organisms quickly regained normal function and metabolic activity with no long-term negative effects. If Roth and colleagues are able to replicate these findings in lar...

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

...h Bio study may be particularly useful if Enigmols enter human clinical trials because the patients will have undergone, and will probably be undergoing, other treatments anyway, he added. In addition to Merrill, Peng and Liotta, the research team is also comprised of: researcher Cameron Sullards of Georg...

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