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Tag: "enhance" at biology news

Molecular cabal contributes to stroke damage

...ts on a particular ASIC, called ASIC1a, to greatly enhance its sensitivity to the acid induced by ischemia. This increased sensitivity causes the ASIC channel to open and flood the neuron with lethal doses of calcium. Importantly, the researchers found in cultures of neurons that drugs that inhibited NMDAR ...

Good news for the medical marijuana movement: pot proliferates brain cells and boosts mood

...binoids are perhaps the only illicit drug that can enhance adult neurogenesis and subsequently modify behavior. ...

Building a better mouse model of lung cancer: FHIT counts

...in with the loss of another tumor suppressor might enhance the research value of the new mouse model even more, so the research team bred another strain of mice that coupled the lack of the protein with partial loss of a second tumor suppressor gene, VHL, which also sits on chromosome 3 in humans. (Mice with...

Plant wounds trigger bacteria

...ation of the plasmid. The extra copies of this DNA enhance the ability of the bacterium to cause tumors, which grow when a fragment of the plasmid DNA invades the plant's own DNA. Crown gall tumors mostly strike the trunks or stems of dicot plants, tree or vines near the ground where freezing occurs during...

Scientists and engineers apply nature's design to human problems

...sustainable and thus have the potential to greatly enhance new technologies, materials and processes. "Biology can be a powerful guide to understanding problems in design and engineering," said Associate Professor of Biology Marc Weissburg, CBID co-director. "In comparative physiology, we teach that every a...

U-M scientists discover identifying markers for primitive blood-forming stem cells

...n human HSCs, these new markers could dramatically enhance the purification of such cells, potentially making bone marrow transplants safer and more effective," says Morrison, who adds that Kiel and Yilmaz have already started tests to look for them. Toshide Iwashita, M.D., Ph.D., a former research fellow i...

NHGRI expands effort to revolutionize sequencing technologies

...emistry, chemistry and physics with engineering to enhance the whole effort to develop the next generation of DNA sequencing and analysis technologies. "It is very important that we encourage and support the variety of sequencing technology projects that hold the most promise for revolutionizing genome sequ...

UW-Madison scientists zero in on drugs' sweet spots

...pecify the role of the sugar and make new drugs or enhance old ones to greater precision and effect. The seri... Thorson's team, for example, may help researchers enhance the anti-cancer effects of digitalis and downshift its influence on the heart, thus avoiding potenti...

Promising therapies for haemophilia & heart disease

...ignificantly to effective strategies to inhibit or enhance P-selectin depending on clinical need". ...

Stressed cells spark DNA repair missteps and speed evolution

...n repair will affect some other gene. It can also enhance the likelihood of two mutations occurring in the same gene or neighboring genes. "This can speed evolution of complex protein machines." Rosenberg said. ...

Sensor web simulation investigates technique to improve prediction of pollution across the globe

...ow such a model-driven sensor web could be used to enhance current measurement techniques, and bring to bear multiple complementary instruments to respond to rapidly changing environmental conditions. "These simulations fall into the category of 'proof of concept,' to assess the feasibility of what is also ...

New understanding of jet lag

...d" could be made stronger, such as using a drug to enhance GABA, the ventral and dorsal parts of the central timekeeper could more quickly move back into harmony. The symptoms of jet lag would then be reduced or eliminated. "The key here is, we now know what the 'rubber band' is: the neurotransmitter GABA t...

Progress on HIV/AIDS significant but insufficient

... up special programmes for women and girls, and to enhance efforts to eliminate violence against women and educate men and boys. Prevention was reaffirmed as the pillar in combating AIDS in another round-table discussion, but coverage of prevention programmes was still low. Globally, fewer than one person i...

Weight control protein may yield antiobesity drugs

...oth leptin and insulin, action drugs that mimic or enhance SH2-B action may improve insulin and leptin sensitivity and have potential value in treatment of obesity and type 2 diabetes," he added. ...

Nanoscale method for investigating living systems

... these quantum dots can form artificial pores that enhance the flow of ions and which we can control from the outside via voltage." Quantum dots can be encoded with different colors making them useful as fluorescent labels for staining cells. Their resistance to photobleaching and physical size of less than...

Traditional models underestimate extinction rates

...opulation density--to accurately evaluate risk and enhance recovery programs for at-risk populations. As threats to endangered species continue to mount, biologists will need ever more robust methods to estimate extinction risk. Unfortunately, field biologists typically can't generate the large, high-quality...

Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy

...nd that are activated by the hormone adrenaline to enhance the heart's pumping action in response to exercise or stress. In heart failure patients, chronic stress leads to an excess of adrenaline, over-stimulating beta-adrenergic receptors, a process that results in receptor desensitization and loss, Rockma...

Device traps, disables harmful bacteria

...aerosols researchers believe, creates harbors that enhance the aerosolization of microorganisms, including strains of Legionella and Mycobacterium, that can cause diseases such as "lifeguard lung." "The results of this study suggest that a reasonable reduction in bioaerosol concentrations can be achieved by...

IBM Transforms the Art of Scientific Expeditions

Scientists have shown they can dramatically enhance radiation's cancer-killing effects by blocking a "master switch" in cancer cells that promotes cancer growth. Blocking a protein called HIF-1 after radiation therapy doubled the length of time it took for human cancers to begin growing again in mice,...

Duke Experiments Boost Radiation's Cancer-Killing Effects

Scientists have shown they can dramatically enhance radiation's cancer-killing effects by blocking a "master switch" in cancer cells that promotes cancer growth. Blocking a protein called HIF-1 after radiation therapy doubled the length of time it took for human cancers to begin growing again in mice,...

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