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Tag: "enhance" at biology news

Stem cell transplants improve recovery in animal models for stroke, cerebral palsy

... or newborns with cerebral palsy can significantly enhance recovery from these types of injuries, researchers say. Using a commonly utilized animal model for stroke, researchers administered a dose of 200,000-400,000 human stem cells into the brain of animals that had experienced significant loss of mobilit...

Data published in PNAS show antibodies can be made 10 times more toxic to cancer cells

... improved cell cytotoxicity. These can be used to enhance the potency of nearly any antibody under development today," Dahiyat added. ...

Paleontologists learn how not to become a fossil

...dy of clam preservation. Their work is intended to enhance evolutionary studies by determining what's missing from the fossil record and why. "Everyone talks about how imperfect the fossil record is, but not many people do anything about it," said David Jablonski, the William Kenan Jr. Professor in Geophysi...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...ug that binds there and controls flap motion could enhance the ability of the current protease inhibitors to bind to the active site, or it could offer a new way of inhibiting protease activity from afar by itself, Perryman suggested. Now that he can prevent the simulated flaps from opening by using an ar...

Computer simulation hints at new HIV drug target

...ug that binds there and controls flap motion could enhance the ability of the current protease inhibitors to bind to the active site, or it could offer a new way of inhibiting protease activity from afar by itself, Perryman suggested. Now that he can prevent the simulated flaps from opening by using an ar...

Scientists re-engineer a well-known antibiotic to counter drug resistance

...breakthrough technology could be used to alter and enhance their therapeutic properties," Boger said. "We hope that our pioneering efforts will spur further research into the development of more potent antibiotics." ...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...opulation studies, to speed up data processing, to enhance accuracy and to reduce cost. With the $14 million annual investment in the environmental component of this initiative, NIH will develop technologically advanced measures of dietary intake, precise personalized measures of physical activity, and biol...

Climate change drives widespread amphibian extinctions

...to the scientists, the Earth's rising temperatures enhance cloud cover on tropical mountains, leading to cooler days and warmer nights, both of which favor the chytrid fungus. The organism grows and reproduces best at temperatures between 63 to 77 degrees Fahrenheit (17 to 25 degrees centigrade). The fungus...

Removing DNA repair gene causes metabolic syndrome

...e could be a drug discovery mechanism in which you enhance the transcription process (of NEIL1) and just make more. Maybe you only have one good copy. Fine. Maybe we can upregulate that one." More importantly, "What we think this publication is going to do is add one more complexity to the potential mechani...

High resolution 'snapshots' detail dynamics of a cocaine antibody

...he humanization and mutagenesis of the antibody to enhance its cocaine-hydrolyzing activity and make future human clinical trials feasible. "Given the fact that catalytic antibodies have been produced with the same levels of efficiency as natural enzymes, it seems well within the realm of possibility," he ad...

Chemical guidance of T cells leads to immunologic memory and long-term immunity

...that may lead to new ways of thinking about how to enhance certain immune responses and how to improve vaccines. Led by immunologist Ronald Germain, M.D., Ph.D., the scientists took videos through a microscope to document what happens inside the lymph nodes of a living mouse shortly after a vaccination. The...

HortResearch science reveals the natural potential of apples

...sing the ESTs into the public domain will serve to enhance the speed of discovery. "We will see a multiplier effect, where discoveries made in other countries will benefit our work and speed up cultivar development. There will also be opportunities for HortResearch to become involved in collaborative resear...

Botox could help target resistant tumors for treatment

...sels, improve tumor perfusion and oxygenation, and enhance the response of tumors to radio- and chemotherapy." Botulinum toxin is a naturally occurring molecule, and historically has been implicated with intestinal poisonings. It has been developed for several clinical applications, including facial spasms,...

Attractive birds more immune against bird flu

...oduce the most antibodies. The findings not only enhance our understanding of why animals behave and look the way they do but also help explain why animals that choose their own mates produce healthier offspring than animals whose mates are selected by humans. ...

UC San Diego partners with Venter Institute to build marine microbial genomics cyberinfrastructure

...ellor for Research. "The new resource will greatly enhance our health science researchers' ability to advance the development of new drugs and therapies from the ocean's resources to combat cancer and neurodegenerative and other diseases." Venter Institute will make available a large collection of community...

Anthrax inhibitor counteracts toxin, may lead to new therapeutics

...t this approach also could be used successfully to enhance the potency of polyvalent inhibitors directed to this target and, they suggest, others. They note the work also could be useful for creating specific target recognition in biological sensors. The team says their work demonstrates for the first time ...

Both alcoholism and chronic smoking can damage the brain's prefrontal cortex

...ity of Utah co-investigators are Normann, who will enhance the electrode array's capabilities for operating the bionic arm; bioengineering Professor Patrick Tresco, who will test the interface device and its components to ensure they are safe when implanted in people; Reid Harrison, an assistant professor of...

University of Utah to help build bionic arm

...ity of Utah co-investigators are Normann, who will enhance the electrode array's capabilities for operating the bionic arm; bioengineering Professor Patrick Tresco, who will test the interface device and its components to ensure they are safe when implanted in people; Reid Harrison, an assistant professor of...

Testes to incubate stem cells

...oblast growth factor (FGF) seem to be necessary to enhance cell growth. The team's next move is to transplant monkey and human cells into the mouse testes system. "It is truly remarkable that mouse testes can sustain these bovine cells in culture," says Elaine Dzierzak, who coordinates a EuroSTELLS project ...

Activation of a protein solidifies fear memory in the brain

...ivation of protein kinase A (PKA) is sufficient to enhance memory reconsolidation and strengthen a previously established fearful memory. Conversely, inhibiting PKA in the amygdala disrupted memory reconsolidation. "These findings show bidirectional behavioral plasticity after memory retrieval," Taylor said...

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