Tamoxifen-like drug suggests new ways to selectively block estrogen
...olecules, called coactivators or corepressors, can enhance or repress the effects of estrogen. They are present at different levels in different tissues. "H12 positioning is essential for these interactions," Greene said. "By changing the conformation of the estrogen receptor, this drug changes the way it i...Researchers Closer To Helping Hearing-Impaired Using Stem Cells
...ese molecules before transplantation might greatly enhance the possibility that the process would result in development of specific sensory neurons.?/p> The research was published March 18 in the online early edition of the Proceedings of the National Academy of Sciences, and is scheduled to appear in th...Chemists synthesize molecule that helps body battle cancers, malaria
... produce new molecules similar to QS-21A that will enhance the body's natural immune response to eradicate diseases." ...Engineers improve plastic's potential for use in implants by linking it to biological material
...y an electric field to this synthetic material and enhance neurite repair," said Schmidt. The newly gained ability to attach proteins to polypyrrole, she said, will mean that growth-enhancing factors could also be linked to this plastic wrapping, further stimulating neurite regeneration. Working with Schmid...'EuroVacc 02' HIV Vaccine Trial Begins
...mmune system whereas the second injections further enhance (boost) the immune response. Therefore this combined vaccine strategy is expected to strengthen stimulation of the immune response While there is a need to identify the best candidates for the "prime" and the most efficient for the "boost", results ...Nature provides inspiration for important new adhesive
...uld improve both work and living environments, and enhance the global competitiveness of U.S. companies, researchers say. They can also provide another market for the nation's soybean farmers - the new adhesives use a tremendous amount of soy flour. ...Science study holds implications for gene therapy and stem cell biology
...bled retroviruses as a tool to discover genes that enhance the fitness of stem cells. Such genes are of great...ould be to increase the availability of genes that enhance stem cell fitness using this novel approach. Simultaneously, we need to study whether similar genes ...Doctors closer to using gene analysis to help trauma patients
...chers want to understand the genetic features that enhance a patient’s recovery as well as the elements that cause people to die sometimes weeks after an injury occurs. Identifying those factors could help physicians choose the best treatment, a decision that could mean the difference between life and death,...A little stress gives beneficial oomph! to immune system
...ncrease in leukocyte activity and availability may enhance the immune system's ability to protect the body during surgery, vaccination or during an infection". But there is also a downside ?ushering an increased number of immune cells to sites of potential immune reaction could worsen pre-existing inflammat...Brain-injury rehabilitation depends on acetylcholine circuitry
... have discovered. Their finding in rats could help enhance rehabilitation to recover from such injuries by le...to the development of drugs or other treatments to enhance the "cholinergic system." The researchers said that their finding that the cholinergic system is in...NASA study finds snow melt causes large ocean plant blooms
...g to Goes, while large blooms of phytoplankton can enhance fisheries, exceptionally large blooms could be detrimental to the ecosystem. Increases in phytoplankton amounts can lead to oxygen depletion in the water column and eventually to a decline in fish populations. The Arabian Sea hosts one of the world'......rstanding how HER receptor degradation works could enhance weak therapeutic efficacy, as well as provide ways to sensitize patients to overcome inherent or acquired resistance to cancer treatment," says Yarden. Prof. Yosef Yarden's research is supported by the Y. Leon Benoziyo Institute for Molecular Medici...Reservoirs may accelerate the spread of invasive aquatic species, researchers say
...ypothesis suggests that these characteristics will enhance the susceptibility of reservoirs to invasion. Because reservoirs are more saline that freshwater lakes, Havel, Lee, and Vander Zanden propose they could provide a haven that helps invaders from saline and brackish habitats adapt to fresh water. Seve...Scientists discover how plants disarm the toxic effects of excessive sunlight
...increase in singlet oxygen. By modifying plants to enhance the protective pathway, "we could be able to get l...minimize the harmful effects of singlet oxygen and enhance energy production." Reactive oxygen also plays an important role in human, animal and plant health,...Transgenic plants remove more selenium from polluted soil than wild plants, new tests show
...id Terry. "This is something we've been working to enhance in our lab. Getting inorganic selenium into gas form will allow it to just dissipate harmlessly into the atmosphere. No other form of remediation can do that." And what happens to the plants after they've soaked up their share of selenium? The resea......oup of coactivators, when brought to the gene, can enhance the amount of RNA made off the gene or the quantitative expression of that gene as well as qualitatively change what comes off the gene in terms of what protein is made," said O'Malley. These coactivators are unusual in that they can both control alt...New online portal merges vast data on Gulf of Maine ecosystem
...e, online at http://gmbis.iris.usm.maine.edu, will enhance current understanding of the complex marine ecosys...mation together in one place. "This new tool will enhance our understanding of biological patterns in the Gulf of Maine, across space and time, and illuminate...Drug-resistant bacteria on poultry products differ by brand
...dard isolation methods and new methods modified to enhance detection of fluoroquinolone-resistant Campylobacter, they compared retail products purchased at grocery stores in Baltimore, Md. A high percentage of the products from the two conventional brands were contaminated with fluoroquinolone-resistant Camp...Effective Cancer Treatments Follow The Clock
... provide a rationale for developing drugs that can enhance the therapeutic index through the modulation of the circadian clock. We have already started screening sets of chemical compounds for their ability to affect this function. We are also planning additional studies to discover the molecular signals fro...Children's taste sensitivity and food choices influenced by taste gene
...dren by allowing us to devise better strategies to enhance fruit and vegetable acceptance in children who are sensitive to bitter taste," comments Mennella. "It may be that childhood represents a time of heightened bitter taste sensitivity in some children, which lessens with age. Such a scenario would accou...