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Tag: "encapsulated" at biology news

Novel antiviral technology inhibits RSV infection in mice

...mall fragments of RNA (siRNA). These fragmentswere encapsulated within chitosan nanoparticles -- minisculenaturally-occurring, biodegradable particles that stick tomucous-producing cells lining the lungs. The RNA produced isspecifically designed to suppress the protein NS1. Without NS1, thehost antiviral defense ...

Self-assembled DNA buckyballs for drug delivery

...structures were made, suggests that drugs could be encapsulated in buckyballs to be carried into cells, where natural enzymes would break down the DNA, releasing the drug. They might also be used as cages to study chemical reactions on the nanoscale, he says. The nanoscale, hollow buckyballs are also the first...

'Cookbook recipes' would cure disease with nontoxic DNA delivery systems

...s also produced inverted hexagonal structures with encapsulated DNA. "First, the strands of DNA are coated with positively charged ions," Wong said. "The strands are then wrapped with negatively charged lipids and resemble tubes, which are then grouped into hexagonal arrangements." Utilizing naturally occurring ...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

...ompatible and biodegradable PLA polymer system and encapsulated a fluorescently labeled model drug within them, in... which have the chemotherapeutic agent, docetaxel, encapsulated within the nanoparticles are remarkably promising. In close collaboration with Dr. Robert Langer at ...

Researchers use 'trickery' to create immune response against melanoma

...ompatible and biodegradable PLA polymer system and encapsulated a fluorescently labeled model drug within them, in... which have the chemotherapeutic agent, docetaxel, encapsulated within the nanoparticles are remarkably promising. In close collaboration with Dr. Robert Langer at ...

Chemotherapy gel may fight breast cancer and reduce breast deformity

...d radiation." To test their idea, the researchers encapsulated a common breast cancer chemotherapy drug, doxorubicin, in microspheres, or beads, and then mixed them with a gelatin made of a polymer substance. Mice with breast cancer tumors were treated by inserting the gel under the skin next to the mammary glan...

Bioactive cement scaffold may improve bone grafts

... a bone cavity and then allowed to harden with the encapsulated cells dispersed throughout the structure. The natural polymer beads gradually dissolve when exposed to the body's fluids, creating a scaffold that is filled by the now released bone cells. The cement, a calcium phosphate material, is strengthened by...

Sandia work launched on space shuttle shows live cells influence growth of nanostructures

...immins of UNM's College of Pharmacy notes that the encapsulated cells' unusual longevity may serve as a model for persistent infections such as tuberculosis, which has a long latency period. TB bacteria can remain dormant in vivo for 30-50 years and then re-activate to cause disease. Presently the state of the do...

Bubbles go high-tech to fight tumors

... a two-step process, Bull said. First, a stream of encapsulated superheated perfluorocarbon liquid droplets goes into the body by way of an intravenous injection. The droplets are small enough that they don't lodge in vessels. Doctors image the droplets with standard ultrasound, and once the droplets reach their ...

Students invent protective pouch to enhance cell therapy

...lood flowing through the vessel should nourish the encapsulated cells and circulate the proteins, such as insulin,...ts have provided an ideal environment in which the encapsulated cells can thrive." Along with other undergraduate projects, this prototype was unveiled May 2 at ...

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