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Tag: "enabled" at biology news

Polymer aids in blood clotting, pointing way to new treatment

...ion of the acidocalcisome in various organisms has enabled scientists to detect muscle-like motors that operate a variety of movements within cells, said Arthur Kornberg, who won the 1959 Nobel Prize in Medicine or Physiology for discovering mechanisms in the synthesis of ribonucleic acid and deoxyribonuclei...

St. Jude projects 90 percent cure rate for ALL

...authors said. Research findings at St. Jude have enabled clinicians to identify patients for whom standard ...actors putting patients at high risk; and that has enabled us to determine whether treatment failure is due to resistance of leukemic cells to drugs, or merely...

A new way of looking at molecular motors

...ns after they discovered that the molecular motors enabled toxoplasmosis and malaria parasites to force their way into human cells. The researchers say that although their research is theoretical and a long way from clinical applications, the new classification system will help other researchers address im...

Biologists visualize protein interaction that may initiate viral infection

...at Columbia University provided a cloned gene that enabled the Purdue scientists to produce the CRD. The CRD is part of a protein receptor molecule called DC-SIGN - or dendritic cell-specific ICAM3 grabbing non-integrin. ICAM stands for intercellular adhesion molecule, a family of cell proteins that viruses...

Jefferson researchers building a better rabies vaccine

...n a "safe" virus extremely deadly. The finding has enabled the researchers to refine a vaccine they previously created against rabies in wildlife, making it safer and more effective. "We have identified a molecular mechanism involved in making the rabies virus pathogenic and lethal, and have developed a ver...

Legume compounds may help cancer treatment

...unding has been vital in building capacity. It has enabled this marvellous research outcome," Professor Gresshoff said. ...

'Shuttling' protein possibly key to resilience of cancer cells

... illuminated with a light source. The fluorescence enabled the researchers to pinpoint the location of c-Jun-ATF2 heterodimers and discover the shuttling movements of ATF2. The ATF2 protein also has been found in the cytoplasm of diseased brain cells in Alzheimer's disease and muscle cells in the heart, sugg...

Unraveling the viral mechanism

...image reconstruction algorithm. These developments enabled him and his co-authors at MIT to see through the bacteriophage at very high resolution. "It turns out that, in addition to the surface protein, there are other proteins that make this virus viable," said Chiu. In particular, proteins protruding a...

New fruit fly protein illuminates circadian response to light

...ant fruit fly that possesses jetlag-like behaviors enabled senior author Amita Sehgal, PhD, Professor of Neuroscience at Penn and a Howard Hughes Medical Institute (HHMI) Investigator, and colleagues to identify the gene and subsequent protein that aids in the response of the internal biological clock to lig...

Brittle prions are more infectious

... the researchers created a mathematical model that enabled them to describe the growth and replication of prions according to the physical properties of the prion protein. To validate that model in yeast, they then created in a test tube, infectious forms of the prion protein in three different conformations...

Radioactive scorpion venom for fighting cancer

...adiation that kills the cell. This compound has enabled an experimental treatment for high-grade gliomas, found in 17,000 people in the US every year and usually causing death in the first year of diagnosis. Patients would simply be injected with the compound in an outpatientprocedure, without needing ch...

Mitochondrial DNA sequencing tool updated

...ut those of the variations. The Affymatrix chip enabled laboratories to resequence the mitochondrial genome much faster than the traditional manual and automated strategies. Just as importantly, like an iPod to music lover, the chip served as the broad technological platform for laboratories to customize...

The brain's executive is an 'event planner'

...ion with pauses in between. This stepwise approach enabled the researchers to distinguish whether the lateral PFC neurons were active during planning the movements or planning the events that would result from those movements. "We found that neurons in the lateral PFC exhibited substantial changes in activ...

Himalayan forests disappearing

...ion with pauses in between. This stepwise approach enabled the researchers to distinguish whether the lateral PFC neurons were active during planning the movements or planning the events that would result from those movements. "We found that neurons in the lateral PFC exhibited substantial changes in activ...

Pathway toward gene silencing described in plants

... toolkit is really powerful," Pikaard said. "It enabled us to look at a complex pathway and figure out not only the order of events but also the spatial organization of the pathway in the nucleus. Our hope for the future is to develop tools that will enable us to watch the pathway function in live cells ...

UCSD researchers develop 'smart petri dish'

... silicon crystals with nanometer-sized holes. This enabled them to produce a photonic crystal, capable of controlling light within the structure analogous to the way that semiconductors transmit electricity through computer chips. By attaching rat liver cells to the polystyrene within the crystals and measur...

Funding and bureaucracy, not access to journals, are chief obstacles to scientific productivity

...r with an analysis of the peer-reviewed literature enabled the team to identify a list of 16 key factors. Online polling methods in conjunction with conjoint analysis techniques were used to establish the relative priority that researchers place on each of these 16 factors. The results were highly consiste...

Nanotubes used for first time to send signals to nerve cells

...bes (SWNTs) deposited on transparent plastic. This enabled the researchers to use a microscope to position a tiny electrode next to individual cells and record their responses to electrical pulses transmitted through the SWNTs. In addition to their electrical stimulation experiments, the scientists also stu...

MRSA vaccine shows promise in mouse study

...up B meningococci. Access to the S. aureus genome enabled the team to compile a list of cell-surface antigens from diverse strains of the bacteria, many of them new targets. From that list, Schneewind and colleagues selected 19 potential vaccine targets taken from eight different strains of S. aureus. B...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...s cancer cells to self-destruct. The method also enabled researchers to match up a pair of natural products, known as celastrol and gedunin, with a mechanism by which some advanced prostate tumors continue to grow aggressively despite hormone-blocking treatments. A paper in Cancer Cell reports on this work...

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