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Tag: "emory" at biology news

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

Physicians at Emory University School of.Medicine are conducting a clinical trial using stem cells generated.within the bone marrow to grow new blood vessels that could improve.circulation in patients with blockages in the arteries of their legs --.a condition called .(PVD). Individuals with PVD have decreased blood flow to the muscles of.the legs, especially during exercise, which causes pain,...

Researchers Uncover Key Step In Manufacture of Memory Protein

A cellular enzyme appears to play a crucial role in the manufacture of a protein needed for long-term memory, according to a team of researchers led by scientists at the National Institute of Child Health and Human Development of the National Institutes of Health. .. . “Understanding how BDNF is made may help us to...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

An expanded clinical trial conducted by Optobionics Corporation involving the implantation of a retina mircrochip has allowed Emory Eye Center and the Atlanta Veterans Affairs Rehabilitation Research & Development Center to implant the device in several patients. The patients all have retinitis pigmentosa with moderate-to-severe vision loss. Three centers in the United States have been chosen...

Nanogen Issued Patent for Electronic Microarray With Memory

Nanogen, Inc. (Nasdaq: NGEN), developer of advanced diagnostic products, announced today that it was issued U.S. Patent No. 6,867,048, "Multiplexed Active Biologic Array" by the U.S. Patent and Trademark Office. The '048 patent relates to a method of addressing one or more electrodes (or "test sites") across multiple rows and columns of a microarray. The patent also covers a method for storing th...

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

Underscoring the value of good prenatal care, new research suggests that early infection may create a cognitive vulnerability that appears later during stress on the immune system. Researchers at the University of Colorado at Boulder have reported that rats who experienced a one-time infection as newborns didn't learn as well as adult rats who were not infected as pups, after their immunity was c...

Structure-building cell signals also may influence learning and memory

A Burnham Institute study has found that one of the cell's largest families of signaling molecules, called ephrins, which are known to regulate the development of nerve cells, also controls nerve cells' ability to engulf critical chemicals and proteins for learning and memory. These findings, the first to link these molecular semaphores to this important nerve cell function, appear in the May iss...

Mice brains shrink during winter, impairing some learning and memory

The brains of one species of mouse actually shrink during the winter, causing the mice to have more difficulty with some types of learning, a new study found. .. . .. Th...

Montreal researchers probe the genetic basis of memory

A group of Montreal researchers has discovered that GCN2, a protein in cells that inhibits the conversion of new information into long-term memory, may be a master regulator of the switch from short-term to long-term memory. Their paper Translational control of hippocampal synaptic plasticity and memory by the eIF2a kinase GCN2, which was published in the August 25th issue of the journal Nature,...

New research shows why too much memory may be a bad thing

New research from Columbia University Medical Center may explain why people who are able to easily and accurately recall historical dates or long-ago events, may have a harder time with word recall or remembering the day’s current events. They may have too much memory ?making it harder to filter out information and increasing the time it takes for new short-term memories to be processed and store...

U of MN researchers reverse memory loss in mice

Researchers at the University of Minnesota were able to reverse memory loss in mice with significant brain degeneration for the first time, a breakthrough that offers hope to the estimated 4 million people living with Alzheimer's disease. . Researchers first manipulated the genetic makeup of the mice so they developed dementia; the mice experienced memory loss that worsens over time and had brain...

Researchers know what you were about to say; fMRI used to detect memory storage and retrieval

Using functional magnetic resonance imaging, or fMRI, researchers at the University of Pennsylvania and Princeton University have provided evidence that the act of recalling a memory is a bit like mental time travel. Their study, presented in the Dec. 23 edition of the journal Science, demonstrates that the same areas of the brain that are active during an event are activated when a person attem...

Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace

An international team of scientists for the first time has detected a memory trace in a living animal after it has encountered a single, new stimulus. The research, done with honeybees sensing new odors, allows neuroscientists to peer within the living brain and explore short-term memory as never before, according to scientist Roberto Fernández Galán, a leading author on the report who is current...

Tracking the memory trace

Memory formation follows a dynamic pattern, allowing for retrieval from different areas of the brain, depending on when an organism needs to remember, said a researcher at Baylor College of Medicine. . That is what Dr. Ron L. Davis, professor of molecular and cellular biology at BCM, theorizes, based on his most recent report on the topic that finds a memory trace in Drosophila or fruit flies is...

Learning and memory stimulated by gut hormone

Researchers at Yale School of Medicine have found evidence that a hormone produced in the stomach directly stimulates the higher brain functions of spatial learning and memory development, and further suggests that we may learn best on an empty stomach. . Published in the February 19 online issue of Nature Neuroscience by investigators at Yale and other institutes, the study showed that the hormo...

Mechanism for memory revealed in neurons of electric fish

Researchers from The University of Texas at Austin studying electric fish have gained new insight into how memory is stored at the level of neurons. . .. .. The channels give the fish neurons the ability to r...

Activation of a protein solidifies fear memory in the brain

When activated, a specific protein in the brain enhances long-term storage of fearful memories and strengthens previously established fearful memories, Yale School of Medicine researchers report this week in Nature Neuroscience. . .. She said recent data suggest that memories can continue t...

Chemical guidance of T cells leads to immunologic memory and long-term immunity

In the latest issue of the journal Nature, scientists at the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) describe a new understanding about how long-term immunity works--findings that may lead to new ways of thinking about how to enhance certain immune responses and how to improve vaccines. . Led by immunologist Ronald Germain, M.D., Ph...

Mice lacking social memory molecule take bullying in stride

The social avoidance that normally develops when a mouse repeatedly experiences defeat by a dominant animal disappears when it lacks a gene for a memory molecule in a brain circuit for social learning, scientists funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) have discovered. Mice engineered to lack this memory molecule continued to welcome strange...

Confidence in memory performance helps older adults remember

Believing that you can retain a good memory even in your twilight years is the first step to achieving that goal. Those who believe they can control their memory are more likely to employ mnemonic strategies that help keep memory fit despite the march of time. These are the conclusions of a new Brandeis study published in the Journals of Gerontology: Psychological Sciences. . The study demonstrat...

Drug triggers body's mechanism to reverse aging effect on memory process

A drug made to enhance memory appears to trigger a natural mechanism in the brain that fully reverses age-related memory loss, even after the drug itself has left the body, according to researchers at UC Irvine. . Professors Christine Gall and Gary Lynch, along with Associate Researcher Julie Lauterborn, were among a group of scientists who conducted studies on rats with a class of drugs known a...

Memory loss affects more of the brain than previously thought

Memory loss associated with early Alzheimer's disease (AD) may be linked to altered activity in several areas of the brain, according to a study in the July issue of Radiology. . For the first time, researchers at Duke University Medical Center in Durham, N.C., used a special, high-field- strength, functional magnetic resonance imaging (fMRI) scanner to study the brain activity of people with amn...

Brain enzyme treatment relieves memory lapse in Alzheimer's mice

An enzyme that helps neurons rid themselves of excess or aberrant proteins is required for normal brain function, according to a new report in the August 25, 2006 issue of the journal Cell, published by Cell Press. What's more, by increasing brain levels of the enzyme in mice with Alzheimer's symptoms, the researchers found they could reverse lapses of memory characteristic of the debilitating di...

Mayo Clinic study suggests that a central nervous system viral infection can lead to memory deficits

In one of the first known laboratory studies that explores memory deficits associated with a viral infection of the central nervous system, Mayo Clinic researchers have evidence that this infection can lead to memory loss late in life. The study, which was conducted in animal models, suggests that over the lifetime of an individual, a picornavirus-related infection could possibly have a permanent...

Affymetrix 500K array used to identify memory gene

Affymetrix Inc. announced today that researchers at the Translational Genomics Research Institute (TGen) in Phoenix, Arizona have used the Affymetrix 500K Array to discover a gene--called Kibra--associated with memory performance in humans. The team's findings may be used to develop new medicines for memory-based diseases such as Alzheimer's and Parkinson's by providing scientists with a better u...

How brain injury leads to seizures, memory problems

In a finding that may provide a scientific basis for eventual treatment, neurology researchers have shown that traumatic brain injury reduces the level of a protein that helps keep brain activity in balance. The resulting abnormal activity, in turn, is thought to be an underlying reason for seizures and memory defects experienced by people who have suffered a traumatic brain injury (TBI). . "A tr...

A natural chemical found in strawberries boosts memory in healthy mice

Mothers have long exhorted their children to eat their fruit and vegetables. But once kids are beyond mom's watchful eye, the hated greens often go the way of Barbie dolls and power rangers. Now, there's another reason to reach for colorful fruits past adolescence. ....

Hopkins researchers discover how brain protein might control memory

Researchers at Johns Hopkins have figured out how one particular protein contributes to long-term memory and helps the brain remember things longer than an hour or two. The findings are reported in two papers in the Nov. 9 issue of Neuron. . .. "We think Arc controls how brain cells learn and associate behaviors and...

Tracing the formation of long-term memory

The formation of long-term memory in fruit flies can be demonstrated by the influx of calcium into cells called mushroom body neurons that occurs after special training that includes periods of rest, said researchers from Baylor College of Medicine (BCM) in a report that appears in the current issue of the journal Neuron. . .. Davis and h...

Proteins necessary for brain development found to be critical for long-term memory

A type of protein crucial for the growth of brain cells during development appears to be equally important for the formation of long-term memories, according to researchers at UC Irvine. The findings could lead to a better understanding of, and treatments for, cognitive decline associated with normal aging and diseases such as Alzheimer's. . .. "This study presents strong evidence that a molecu...

Early HIV treatment fails to restore memory T cells

Most of the body’s memory T cells vanish within weeks after a person is infected with the HIV virus. In a study from the Aaron Diamond AIDS Research Center and the Bernard-Nocht Institute appearing in the international open-access journal PLoS Medicine, researchers report that these memory T cells, mostly found in the digestive tract, tend not to return to normal even after years of treatment for...

How the brain weaves a memory

Memories of events comprise many components--including sights, sounds, smells, and tastes. Somehow the many features of an episodic memory are woven together into a coherent whole, and researchers have had little understanding of how this binding takes place as the memories are processed by the brain's memory center, the hippocampus. A central question has been whether the hippocampus receives an...

Anticipation plays a powerful role in human memory, brain study finds

Psychologists have long known that memories of disturbing emotional events - such as an act of violence or the unexpected death of a loved one - are more vivid and deeply imprinted in the brain than mundane recollections of everyday matters. . .. That means the simple act of anticipation may play a surprisingly important role in how fresh...

Experience affects new neuron survival in adult brain; study sheds light on learning, memory

Experience in the early development of new neurons in specific brain regions affects their survival and activity in the adult brain, new research shows. How these new neurons store information about these experiences may explain how they can affect learning and memory in adults. . A team of researchers headed by Fred Gage, PhD, of the Salk Institute, found that experience enhances the survival...

UCLA/Toronto researchers unlock key to memory storage in brain

Scientists know little about how the brain assigns cells to participate in encoding and storing memories. Now a UCLA/University of Toronto team has discovered that a protein called CREB controls the odds of a neuron playing a role in memory formation. The April 20 edition of Science reports the findings, which suggest a new approach for preserving memory in people suffering from Alzheimer's or...

Sleep enforces the temporal sequence in memory

We have usually quite strong memories of past events like an exciting holiday or a jolly birthday party. However it is not clear how the brain keeps track of the temporal sequence in such memories: did Paul spill a glass of wine before or after Mary left the party? . Previous findings from a research group headed by Jan Born at the University of Lübeck have confirmed the widely held view that lo...

Mutation improves memory, may lead to memory-enhancing pill

A mind-altering mutation in mice results in an enhanced long-term memory, researchers report in the April 6, 2007 issue of the journal Cell, published by Cell Press. These findings point to a potential target for the development of a drug to treat memory loss, according to the researchers. . The researchers studied a gene that normally increases levels of a natural memory-blocking protein. Animal...

Latent memory of cells comes to life

New Danish research has examined the mechanisms behind latent cell memory, which can come to life and cause previously non-existent capacities suddenly to appear. Special yeast cells for example, can abruptly change from being of a single sex to hermaphrodite. . Researchers from the Niels Bohr Institute at the University of Copenhagen have used mathematical models and computer simulations to ex...

New Brandeis research sheds light on memory by erasing it

For years, scientists have studied the molecular basis of memory storage, trying to find the molecules that store memory, just as DNA stores genetic memory. In an important study published this week in the Journal of Neuroscience, Brandeis University researchers report for the first time that memory storage can be induced and then biochemically erased in slices of rat hippocampus by manipulating...

Statin treatment improves spatial memory in mouse models of Alzheimer's

Treatment with Simvastatin, one of the statin drugs widely used for lowering cholesterol in humans, significantly improved spatial memory - how to navigate a water maze - in mice genetically bred to have an Alzheimer’s like disease. Although statin improved memory in both males and females, the results were more pronounced in males. . Dr. H. A. Morcos, chair of Pharmacology at the American Univer...

How 'memory' T cells curb the spread of viruses throughout the body

. After becoming sick from many viruses, the body becomes “immune” (protected) from recurrence of the same disease. This is why before vaccines were developed, childhood diseases suc...
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