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Tag: "elucidation" at biology news

Beyond the DNA: Chemical signatures reveal genetic switches in the genome

...the sequence features that identify enhancers. The elucidation of a common histone modification signature will enable scientists to quickly identify enhancers and promoters for a gene, which will lead in turn to rapid identification of factors that control its expression." This method might also be used to ident...

ATR checkpoint-activating DNA structure

...tural information is quite novel and valuable. The elucidation of the first defined DNA structure capable of eliciting the ATR checkpoint will aid researchers to further identify additional checkpoint proteins, as well as understand how checkpoint signals are generated and regulated inside the cell....

Ancient immune defense mechanism is no match for HIV-1

...are form of immunity in vertebrate cells. However, elucidation of the mechanism HIV-1 uses to protect itself provides some critical insight into a potential vulnerability within the HIV-1 molecule. Identification of what might be a long sought after weakness in the virus may have application for rational design ...

Scientists solve structure of key protein in innate immune response

...cal Chemistry, scientists in Korea announced their elucidation of three-dimensional structure of CD14 and showed how it is perfectly suited to bind to certain bacterial products. The research appears as the "Paper of the Week" in the March 25 issue of the Journal of Biological Chemistry, an American Society for...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...an cell," says Gourley, "the key discovery was the elucidation of biophotonic differences in normal and cancer cells by using intracellular mitochondria as biomarkers for disease. This technique holds promise for detecting cancer at a very early stage and could nearly eliminate delays in diagnosis and treatment....

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...rs at a time, evidence that made possible the full elucidation of the code by 1966. Crick then turned to developmental biology, the study of how genes control the growth and specialization of organs. In 1976, Crick moved to the Salk Institute for Biological Studies in La Jolla, California, where he took up neur...

Essential mangrove forest threatened by cryptic ecological degradation

...tal mangrove lagoons into freshwater bodies. Such elucidation of past ecosystem processes and human-environment interactions is an essential part of the Past Global Changes (PAGES) project of the International Geosphere-Biosphere Programme (IGBP), funded by the U.S. and Swiss National Science Foundations as wel...

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