Excess liver gene protects against high-fat diet
... lipid metabolism," said Lazar. "The current study elucidates a previously unrecognized role for these liver receptors in the links between diet, serum lipids, and atherosclerosis." Selective modulation of the LXR target genes in liver may therefore ameliorate high lipid levels and cardiovascular disease, the ...Variation in HIV's ability to disable host defenses contributes to rapid evolution
...variation in the virus within patients. "This work elucidates new pathways which shape the evolution of the virus," says Viviana Simon, lead author of the study. ### Citation: Simon V, Zennou V, Murray D, Huang Y, Ho DD, et al. (2005) Natural variation in Vif function can differentially impact APOBEC3G/3F neu...