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Tag: "elucidate" at biology news

Baumann Lab defines proteins that distinguish chromosome ends from DNA double-strand breaks

...ting specific proteins, we have opened the door to elucidate the mechanism by which RAP1/TRF2 inhibits double-strand break repair at chromosome ends." "These findings are important for establishing a better understanding of tumor development," said Robb Krumlauf, Ph.D., Scientific Director. "Genomic instabi...

Genome of yellow fever/dengue fever mosquito sequenced

...enome sequence is expected to stimulate efforts to elucidate interactions at the molecular level between mosquitoes and the pathogens they transmit to humans. ...

Bats prey on nocturnally migrating songbirds

...f metres above the ground in total darkness? To elucidate the mysterious habits of giant noctule bats, an ambitious investigation led by young scientist Ana Popa-Lisseanu, under Prof. Ibañez' supervision, was launched by Spanish research teams based in Sevilla (Doñana Biological Station) and Granada (Zaidín...

New imaging technique tracks traffic patterns of white blood cells

...ling techniques will greatly aid investigations to elucidate in vivo imflammatory cell behavior, and provide a powerful tool for the development of therapeutics for these diseases," according to Mount Sinai researchers. "Sickle cell anemia was the first disease characterized at the molecular level but ther...

Genome archaeology illuminates the genetic engineering debate

...dified organism (GMO) controversy. "Our findings elucidate an active evolutionary process in which nature inserts genes much like modern biotechnologists do. Now we must reassess the allegations that biotechnologists perform 'unnatural acts,' thereby creating 'Frankenfoods,'" said Professor Joachim Messing, ...

How blood flow dictates gene expression

...healthy cardiovascular system, the next step is to elucidate the role of Klf2 in normal adult blood vessels and in the pathogenesis of vascular diseases, such as atherosclerosis. ...

Researchers add to understanding of how brain cells communicate

...inputs. In this paper, Johnson and Qian further elucidate how NR1/2D receptors do this. Johnson was most surprised to find that the magnesium ion, which strongly blocks the channels of NR1/2A receptors, flows much more easily in NR1/2D receptors. In those receptors, magnesium acts more like a "permeant" ion...

Green tea and the 'Asian Paradox'

...ical health. "More studies are necessary to fully elucidate and better understand green tea's method of action, particularly at the cellular level," Sumpio said. "The evidence is strong that green tea consumption is a useful dietary habit to lower the risk for, as well as treat, a number of chronic diseases. ...

Gene linked to rare disease activates fat breakdown

...d in the May Cell Metabolism reveals. The findings elucidate the mechanism underlying healthy fat metabolism and explain why people with the genetic condition known as Chanarin-Dorfman Syndrome (CDS), who carry a mutant version of the gene, suffer from the widespread buildup of fat in tissues throughout their ...

Variations in detoxifying genes linked to Lou Gehrig's disease

...teraction and PON serum/enzymatic studies may help elucidate the complexity of PON cluster association with ALS," Siddique said. Siddique hopes to study DNA samples from Gulf War veterans with increased incidence of sporadic ALS and has applied for their DNA from the Veterans Administration collection. ...

Researchers uncover new mechanism of tumor suppressor

...nd other biochemical and biophysical approaches to elucidate three-dimensional atomic-resolution structures and dynamics of proteins to better understand their physiological functions and relevance to diseases. ...

How nice, brown rice: Study shows rice bran lowers blood pressure in rats

...al food,?he said. The researchers?next step is to elucidate the mechanisms by which specific components of rice bran inhibit ACE and lower cholesterol. ...

Nobelist discovers antidepressant protein in mouse brain

...r to achieve their effect." Future studies should elucidate exactly how antidepressants increase levels of this molecule, he added. Also participating in the study: Per Svenningsson, Ilan Rachleff, Marc Flajolet, The Rockefeller University; Karima Chergui, Xiaoqun Zhang, Karolinska Institute; Malika El Yacou...

Strawberries by design

...candidate as a platform for large-scale studies to elucidate gene function. The new protocol involves taking strawberry plant tissue from its original site and transferring it to an artificial medium for growth or maintenance. Here unfolded leaves, known as trifoliate leaves, are able to grow. When collected...

Patterns in genome organization may partially explain how microbial cells work

...rial genomes yielded "scalograms," maps colored to elucidate the strength of a variety of periodicities associated with chromosome position. Just as the wavelet analysis identified significant increases in sea surface temperatures; it also revealed nonrandom patterns in the genomes of the 151 microorganisms st...

Understanding the oceans microbes is key to the Earth's future

...t many unknowns persist and more work is needed to elucidate and understand their complexity," says co-author David Karl of the University of Hawaii. "Uppermost on this list of questions is what effects human-induced changes will have on the services marine microbes perform for the planet. Research on marine ...

Penn study finds direct role for glial cells in brain cross-talk

Findings may help elucidate mechanisms of wake-sleep transitions and epileptic seizures Researchers at the University of Pennsylvania School of Medicine have demonstrated that star-shaped glial cells in the brain called astrocytes are directly involved in regulating communicat...

Solexa and collaborating scientists illuminate the small RNA component of the transcriptome

...wed journal Science. Solexa's assay can be used to elucidate small RNAs in any plant or animal species, notably humans. "Finding that small RNAs comprise a potent set of regulatory molecules in diverse organisms is among the most important discoveries in the past 10 years," stated John West, Solexa's chief ex...

AACR Favors 'full spectrum of stem cell research biology'

...cell biology are: # Human stem cell research will elucidate critical aspects of cell growth and differentiation that are altered during the formation and growth of tumors. # Research on tissue-specific stem cells from adults may reveal the body's innate maintenance and repair mechanisms. # Embryonic stem ce...

New Discovery May Help Doctors Treat Infertility

...inology, used a test tube or in vitro approach, to elucidate the role that estrogen receptors play in ovulation. “The combination of the two different methods, the in vivo and in vitro studies, complement each other nicely and provide more precise answers to the role that the estrogen receptor beta plays in ov...

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