A molecule impedes the destruction of the 'Brucella' bacteria
..., escape destruction within the cells charged with eliminating infectious agents (macrophages). This research has been published in Nature Immunology scientific magazine. Brucella is a model of an intracellular parasite, a category that includes other important bacteria, such as those of tuberculosis or legione...Oxygen increase caused mammals to triumph, researchers say
...ited creatures; the extinction event itself, while eliminating the dinosaurs, did little to further the mammalian domination of the planet. It was the subsequent spreading of shallow seas, the increase in plant life - and photosynthesis - in addition to the consequent increase in oxygen content that gave the mam...Researchers develop new method for facile identification of proteins in bacterial cells
...Instead of spending a lot of time and resources on eliminating the background noise to find the signal, our method increases the signal upfront so that it stands out above the background noise. By forcing an up-regulation of enzyme expression in the bacterium of interest, our target can be identified amidst all ...Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
...s, 30 of the protein's 326 amino acids in hopes of eliminating the elements that suppressed the immune response but retaining enough of the normal protein's structure to generate protective antibodies. Out of 11 altered versions they found one that met both criteria. In mouse and human macrophages, version rV10...UN: World in big ecological mess
...e futures explored, scientists project progress in eliminating hunger, but at far slower rates than needed to halve the scourge by 2015. Changes in ecosystems such as deforestation influence the abundance of human pathogens such as malaria and cholera, as well as the risk of emergence of new diseases. Malaria, f...Fungus Effective Against Winged Termites
...ina, because many current control efforts focus on eliminating termite workers in colonies--not on destroying alates during the crucial period before they form new colonies. Raina stumbled across the novel fungal strain after capturing dozens of swarming alates for other studies. To his surprise, all of the ins...Secret of smallpox's success may lead to bioterror cure
...mmune response to the vaccinia virus by completely eliminating the viral gene that allows pox viruses to hide. The more visible the vaccinia virus is to the immune system, the stronger the immune response should be and the better the body should be able to fight off a smallpox infection. Over the past 15 years,...Cerebral navigation: How do nerve fibers know what direction to grow in?
...odified to lack Vav2 and the related Vav3, thereby eliminating this repellent signal, the mice had abnormal axon projections and defects in neural circuitry formation. The second paper demonstrates the role of a protein called ephexin1 in axon guidance. By itself, ephexin 1 promotes axon growth; neurons from mi...U-M team recovers ancient whale in Egyptian desert
...oxygen to live. Roth hypothesizes that temporarily eliminating oxygen dependence in healthy cells could make them a less-vulnerable target for radiation and chemotherapy and thus spare normal tissue during high-dose cancer therapy. "Right now in most forms of cancer treatment we're killing off the normal cells ...Buying Time Through Hibernation on Demand
...oxygen to live. Roth hypothesizes that temporarily eliminating oxygen dependence in healthy cells could make them a less-vulnerable target for radiation and chemotherapy and thus spare normal tissue during high-dose cancer therapy. "Right now in most forms of cancer treatment we're killing off the normal cells ...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...hat at least a few of the cells acquire a mutation eliminating p53 function just by chance. In the absence of p53...an still become fully cancerous if they succeed in eliminating p53 activity, in effect silencing the command to commit suicide. This situation occurs when increase...UCSD researchers maintain stem cells without contaminated animal feeder layers
...people, they would provoke an immune system attack eliminating their therapeutic value. While several laboratories have attempted to grow stem cells in alternative cultures, problems have remained. In some cases, human feeder layers were developed but this added another measure of complexity to the culture syst...Plant hemoglobins: Oxygen handlers critical for nitrogen fixation
...te of Molecular Plant Physiology have succeeded in eliminating the production of symbiotic hemoglobins in nodules of the model legume Lotus japonicus, enabling researchers to assess for the first time the role and importance of these proteins in plants. The results of the study indicate that symbiotic hemoglobin...Color-blind method opens new doors in DNA sequencing
... to take advantage of the entire visible spectrum, eliminating the problem of cross-talk between dyes, said Metzk...ye gives the same intensity of fluorescent signal, eliminating the need for further software processing to yield readable sequence information. "Genome sequencing...The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life
...ted and viewed along different directions, further eliminating the blurry and unwanted light which prevented scientists from looking deep into tissues in the past. The entire procedure is very fast and in a computer supported post-processing step, one or more stacks of images are assembled into a high-resolution...Tiny particles could solve billion-dollar problem
...y ounce of palladium to maximum efficiency, and by eliminating drilling costs for new wells, construction costs for surface treatment facilities and energy costs of lifting water to the surface. Nanotechnology is critical to the scheme because only a nanoscale catalyst will be efficient enough to provide the th...Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
...nd neither group was allowed to become overweight, eliminating this common risk factor for diabetes. The only difference was that the mothers had been fed differently during the final week. As the young mice matured, the researchers tested their blood glucose (sugar) after meals. At age 2 months, the results we...