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Tag: "eliminating" at biology news

Cells re-energize to come back from the brink of death

...erous cells not only dodge death from apoptosis by eliminating caspase activation, but they also foil CIDC. “Our study sought to understand how a cancer cell without caspase activation bypasses CICD as well,” Green said. The St. Jude team discovered that a cell that lacks caspase activation and cannot under...

Caribbean frogs started with a single, ancient voyage on a raft from South America

... giant waves that devastated the islands, probably eliminating any existing fauna at that time," Hedges said. The original frogs that successfully colonized the Caribbean islands likely hitched a ride on floating mats of vegetation called flotsam, which is the method typically used by land animals to travel a...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents

...urrent cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of di...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

... therapy by the U.S. Food and Drug Administration, eliminating a tremendous regulatory hurdle. If successful, this next study will provide the proof of principle needed for the team to apply for phase I human clinical trials, perhaps within 18 months, Kyrkanides said. Early results, while not yet published, sugg...

8 plants from South Africa may hold potential for treating high blood pressure

...e of the plants tested positive for tannins, hence eliminating any false positive results. Ultimately, the eight plants that showed significant ACEI activity in both extract forms were: Amaranthus dubius, Amaranthus hybridus, Asystasia gangetica, Galinsoga parviflora, Justicia flava, Oxygonum sinuatum, Physa...

Herpes infection may be symbiotic, help beat back some bacteria

... to very carefully weigh the risks and benefits of eliminating a virus that our bodies have established a symbiotic relationship with." Scientists previously used vaccination to eliminate the deadly and highly contagious smallpox virus. Vaccines are currently in use or in clinical trials for several disease-c...

Major gene study uncovers secrets of leukemia

...vival rate of ALL." One potential strategy for eliminating leukemic cells would take advantage of the discovery that mutations in the B-cell differentiation pathway are predicted to prevent progenitors from changing into normally functioning lymphocytes. Normally, the body eliminates differentiated B lymphoc...

Rapid oral HIV test shows great promise according to MUHC-led research

...performed by health workers with minimal training, eliminating the need for specialist laboratory technicians." "Rapid point of care HIV testing is a very important component of HIV control initiatives and programs. In particular, non-invasive, simple, accurate oral fluid-based, rapid tests have the potential...

Billions of dollars saved in US by polio vaccination

...ization, stated that, "as we stand on the brink of eliminating wild polioviruses around the world, these results provide a glimpse of the massive economic benefits of global polio eradication." To date, the Global Polio Eradication Initiative has succeeded in reducing the annual cases of paralytic polio from an ...

Scientists produce neurons from human skin

...them to produce perfectly compatible neurons, thus eliminating the risk of rejection. We could then transplant these nerve cells in the diseased areas of the brain," explains Berthod. "This type of procedure seems particularly interesting for diseases such as Parkinson’s, but it’s all theoretical for now. Before...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...atients unrelated to the donor, without rejection, eliminating the need for donor matching and recipient immune suppression. Once transplanted, the cells promote healing of damaged or diseased tissues. "Because of the participation by top tier sites such as Rush University Medical Center, we were able to cond...

MIT: Pulsing light silences overactive neurons

...t of optical brain prosthetics to control neurons, eliminating the need for irreversible surgery. "In the future, controlling the activity patterns of neurons may enable very specific treatments for neurological and psychiatric diseases, with few or no side effects," said Edward Boyden, assistant professor in...

St. Jude announces breakthrough in eye cancer treatment

...e the chance that their vision can be preserved by eliminating the tumor and preventing its spread from the eye to the rest of the body." The discovery that blocking MDMX releases the apoptosis response in retinoblastoma has important implications for certain forms of adult cancers as well. "Some forms of bre...

Mutant gene causes severe kidney disease in infants

...d with steroid-resistant nephrotic syndrome. After eliminating known mutations, the study team was left with DNA from 12 children with the disease. All 12 had inherited recessive mutations in PLCE1 from both parents. None of the seven different PLCE1 mutations were present in the 138 control subjects in the stud...

Einstein researchers demonstrate a novel approach to treating AIDS

...hat were killed. Both isotopes proved effective in eliminating the virus-infected cells from the mice, which expe...arch at Einstein. "But we currently have no way of eliminating the HIV-infected cells that make these infections chronic. The novelty of this technique is that it ...

Evolution and the workaround

...ted a key cell division gene called MYO1. Surely, eliminating this important gene would shut down cell division. This seemed to be the case in the beginning, and yet as the MYO1 defective cells were cultured and subjected to consecutive rounds of selection for best growers, the yeast came up with new strategie...

Wild tigers need cat food

...ion strategy, along with anti-poaching efforts and eliminating trade in tiger body parts. The nine-year study in India’s Nagarahole National Park found that an average of 23 percent of the park’s tigers either move away or die each year from either naturally or from poaching outside of the park, yet total numbe...

HIV exploits competition among T-cells

...ations, this strategy appears effective at all but eliminating competition among T cells," Deem said. "As a result, HIV remained in a state of permanent latency and was never able to escape the immune system's grasp to develop into AIDS." ...

Malaria vaccine prompts victims' immune system to eliminate parasite from mosquitoes

...led that the antibodies were capable of completely eliminating the ookinettes. The study authors noted that Psv25H, a molecule similar to Pfs25, is found on the surface of ookinettes of another species of Plasmodium that causes malaria, Plasmodium vivax. They wrote that the conjugate technology could be easil...

New path from estrogen to survival in breast cancer cells described

... of breast cancer cells by silencing BCA3, through eliminating its hold on NFkB transcription." Now that this cancer-promoting molecular pathway has been described, Yeh says it might be possible to interfere with a number of the players to inhibit cancer growth. "NEDD8 is key," he said. "It may be possible to ...

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