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Tag: "elevated" at biology news

Age-related changes in DNA repair illuminate the connection between age and genetic damage

...In humans and other mammals, these effects include elevated occurrence of malignancies, osteoporosis, hearing loss, graying of hair, and hair loss. It is also known that DNA damage accumulates with age in cells of a variety of tissue types. Breaks in the DNA chain have a variety of causes and occur frequen...

Gene chip technology shows potential for identifying life-threatening blood infection

...inflammation are subtle and similar - fever and an elevated white blood cell count - making it virtually impossible in many cases even for seasoned doctors to make a diagnosis based on symptoms alone. Non-infectious inflammation is common among ICU patients recovering from surgery, pancreatitis, or trauma fro...

Effective HIV control may depend on viral protein targeted by immune cells

...ffective or might only be generated in response to elevated viral loads. Therefore, the findings of this study, which reflect chronic HIV infection, might not apply in situations in which vaccination generates an immune response before infection occurs. "The possibility that there may be fundamental diff...

Soil nutrition affects carbon sequestration in forests

...ound that trees can only increase wood growth from elevated CO2 if there is enough leaf area to support that g... without adequate soil nutrition, trees respond to elevated CO2 by transferring carbon below ground, then recycling it back to the atmospheric through respirati...

Antioxidant protects against lung damage in silicosis

...molecules that cause direct tissue injury), become elevated in the lungs of chronic silicosis patients and could represent a new treatment approach for the disease. These results appear in the second issue for October 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the Am...

'Tribbles' protein implicated in common and aggressive form of leukemia

...ditionally, expression of the Tribbles protein was elevated in blood samples from AML patients, further suggesting that it contributes to AML. Overall, the findings suggest that Tribbles induces AML by inactivating the C/EBPá protein. The results were published in this week's issue of Cancer Cell. AML is ...

Amateur boxing linked to brain cell injury

...om hits to the head during a bout." They also had elevated levels of glial fibrillary acidic protein, which indicates damage to the astroglia, specialized cells that surround neurons to insulate and support them. An increase in this chemical was also recently found in patients who experienced severe brain i...

New research shows big improvement in survival after stroke

...uce risk factors that can lead to strokes, such as elevated blood pressure, smoking, poor diet etc. Only through this can we reduce the incidence of stroke and ultimately improve stroke outcome."...

Sex and the heart: It's not what you think

... C-Reactive Protein (a marker of infection that in elevated levels has been shown to be a risk factor for cardiovascular disease). This appears to be associated with increased use of hormone-replacement therapy, Crimmins said. Heart disease remains the number one cause of death in the U.S. Funding for the g...

Newly identified biomarker detects and regulates spread of brain tumors

...es back after treatment. The study, ÒAttractin is elevated in the cerebrospinal fluid of patients with malign...ified for the first time that attractin levels are elevated in patients with high-grade astrocytoma," says Erwin Van Meir, PhD, professor of neurosurgery and he...

Engineered yeast speeds ethanol production

...engineered a new strain of yeast that can tolerate elevated levels of both ethanol and glucose, while producing ethanol faster than un-engineered yeast. The work will be reported in the Dec. 8 issue of Science. Fuels such as E85, which is 85 percent ethanol, are becoming common in states where corn is p...

Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses

...own to be high in asthmatics, was also found to be elevated in those with polyps, but the levels of interleuki...n-13 did not have the same predictive value as the elevated expression of AMCase, researchers say. Lane adds that future research will have to determine if hi...

Natural anti-viral enzyme helps keep cancer cells alive, researchers find

...m has studied clinical samples of tumors and found elevated levels of TBK-1, Dr. White said. The TBK-1 action is part of an immune reaction called the "host defense response," which is distinct from the "adaptive" immune process, in which the body creates new antibodies against invading pathogens. A great ...

Early HIV treatment fails to restore memory T cells

... activation in the gastrointestinal tract remained elevated despite treatment. The finding that intestinal immune cells do not return to normal in most people with HIV despite years of treatment raises the concern that clinical problems will result over time. Fortunately, this does not appear to be the cas...

Gene therapy inhibits epilepsy in animals

...njury. Rats that had received the gene therapy had elevated levels of alpha1 proteins and either did not develop spontaneous seizures, or took three times as long to experience a spontaneous seizure, compared to rats that did not receive the delivered gene. In this short-term study, said Dr. Brooks-Kayal, ...

Global changes alter the timing of plant growth, scientists say

...they were surprised to find differing responses to elevated carbon dioxide and nitrogen deposition: Wildflower...ture conditions. But plant growth was delayed by elevated carbon dioxide, consistent with the fact that grasses--which make up the majority of plants in this ...

Molecular 'marker' on stem cells aids research, perhaps therapies

...hemotherapy. “Is the expression of this marker elevated in a tumor" If so, perhaps it might be useful to identify cancer stem cells, but we don’t know yet,?Dr. Perlingeiro said. “That would be a very beneficial application, not just for guiding therapy, but also for early cancer detection and perhaps prev...

Signal protein shows promise for blocking tumor promoters in skin cells

...an promote tumor formation. Src kinase activity is elevated in most skin cancers and in common carcinomas, including those of the breast and colon. At the same time, levels of the signaling molecule Srcasm are typically low in tumor cells, notes senior author John Seykora, MD, PhD, Assistant Professor of Derm...

Proteins may predict lung transplant rejection

...n earlier study from the laboratory had found that elevated levels of human neutrophil peptide (HNP), declinin...s found that HNP was three times more likely to be elevated among those who later suffered chronic rejection. Later analyses identified 265 proteins that wer...

Key to zebrafish heart regeneration uncovered

...uch as axolotls, newts and zebrafish, that have an elevated ability to regenerate lost or damaged tissue," said Kenneth Poss, Ph.D., senior researcher for the team, which published the findings on Nov. 3, 2006, in the journal Cell. First authors of the paper were Alexandra Lepilina, M.D., and Ashley Coon. ...

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