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Tag: "elevated" at biology news

Hot-spring bacteria flip a metabolic switch

...ed that the single-celled cyanobacteria growing at elevated temperatures were specialized for photosynthesis, but it looks like they have a more complicated metabolism than we initially suspected." All cells require nitrogen for making proteins and nucleic acids, but N2 gas from the atmosphere cannot be dire...

Source of crucial immune cell in the skin discovered

...omplications. "It is known that Csf-1 levels are elevated in patients with Langerhans histocytosis," said Dr. Merad. "Our findings indicated that finding ways to lower Csf-1 levels may produce new therapeutics for these patients." ...

Bringing the zoos to the zebras

...g to wait until dusk to drink, Grevy's zebras face elevated risks of predation." In March, two zookeepers from Saint Louis Zoo, two from San Diego Zoo, and one from Minnesota Zoological Park will add their special expertise to the Grevy's Zebras project. They will be able to share first-hand knowledge of Gre...

Darkness unveils vital metabolic fuel switch between sugar and fat

...y something in the blood. Another lab test showed elevated levels of 5'-AMP in the blood of mice exposed to constant darkness compared to those kept in the regular light-dark cycle. To confirm the connection, the team injected 5'-AMP into mice exposed to a regular light-dark cycle. Three to four hours afte...

Spousal illness can trigger partner death

... risk of death increases significantly and remains elevated for up to two years," he notes. The period of greatest risk is over the short run, within 30 days of a spouse's hospitalization or death. Over this time frame, hospitalization in a spouse can confer to a partner almost as much risk of dying as the ac...

Removing DNA repair gene causes metabolic syndrome

...ers, insulin levels four times higher than normal, elevated levels of fat cell byproducts, and many internal organs almost entirely encased in thick pads of fatty tissue. The results are the first to link DNA repair with the metabolic syndrome, and they suggest an important role for the NEIL1 gene product in...

New mechanism for essential genome-wide gene silencing identified

...elomeres has been linked to aging in humans and an elevated risk for aging-related diseases, the most prominent of which is cancer. ...

New test to detect rare proteins in blood

...2/neu positive cancer patients showed dramatically elevated Her2/neu levels (average: 384 ng/ml), while the le...ne out of 10 of the Her2/neu positive patients had elevated Her2/neu levels and one out of four in the Her2/neu negative group had elevated Her2/neu levels. Usi...

Therapeutic prospects beyond Vioxx

...hway called PGE2, the deletion of mPGES-1 actually elevated prostacyclin, the complete reverse of what was observed with COX-2 inhibitors. "Selective inhibitors of mPGES-1 may retain much of the benefit of drugs like Vioxx and Celebrex, while diminishing the risk of heart attack and stroke by having precisely...

Molecular mechanism may explain how fevers spark seizures

...e -- kids get sick and have fevers. Usually, those elevated internal temperatures cause only temporary discomfort, but in some small children they spark convulsions called "febrile seizures." These convulsions are "scary and very upsetting to parents," said Robert L. Macdonald, M.D., Ph.D., professor and ch...

Males with elevated levels of testosterone lead shorter lives but have more success siring offspring

...throughout North America. They injected males with elevated levels of testosterone and found that they had shorter lives but that they were very successful at siring more offspring ? even with females who were mated with other males. "The surprising result was that testosterone-treated males had a higher ove...

Higher carbon dioxide, lack of nitrogen limit plant growth

... plots. The plots were exposed to both ambient and elevated carbon dioxide levels, and varying levels of nitrogen. The study was designed to document plants' ability to grow and flourish in nitrogen-depleted soil, which, scientists believe, will become more common as atmospheric carbon dioxide levels rise. S...

Epstein-Barr virus may be associated with multiple sclerosis

... approximately twice as likely to develop MS. The elevated levels became evident between 15 and 20 years before patients first experienced the neurological symptoms of MS and remained higher afterward, the researchers reported. Researchers don't yet understand how the Epstein-Barr virus causes the body to a...

Big hips, big belly? It's in your genes, Joslin-led study shows

... approximately twice as likely to develop MS. The elevated levels became evident between 15 and 20 years before patients first experienced the neurological symptoms of MS and remained higher afterward, the researchers reported. Researchers don't yet understand how the Epstein-Barr virus causes the body to a...

New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice

... “This is because melatonin concentrations are not elevated during a person’s normal waking hours.?/p> “If the link between light exposure and cancer risk can be confirmed, it could have an immediate impact on the production and use of artificial lighting in this country,?said Richard Stevens, Ph.D., an e...

Contaminants linked to sturgeon decline in Columbia river

...mbia River may be declining due to the presence of elevated amounts of foreign chemicals including DDT and polychlorinated biphenyls in their bodies, according to new studies by researchers at Oregon State University. The research by Carl Schreck and Grant Feist, biologists in OSU's College of Agricultural ...

Brain's own cannabis compound protects against inflammation

...lyzed brain tissue from people with MS, they found elevated levels of AEA, compared to healthy tissue. And in studies with mouse brain slices, they found that inducing damage with a brain-cell-exciting chemical, called NMDA, caused an invasion of the brain's immune cells, called microglia, and an increase in ...

Dying of excitement

...rain deterioration after stroke is associated with elevated levels of glutamate -- the major excitatory neurotransmitter in the mammalian central nervous system (CNS) -- in the plasma and cerebral spinal fluid. One possible explanation for this glutamate build-up, reported online on March 6th in The Journal ...

p53, tumor suppression and aging

...ess less Mdm2 protein than normal mice) which have elevated levels of wild-type p53 activity. The researchers found that even a modest decrease (about 20%) in Mdm2 effectively prevents tumor formation and does not lead to premature aging. Dr. Perry emphasizes that "many people develop cancer at a young age ...

First link of oral bacteria and preterm birth found in human

... after it was determined by low glucose levels and elevated white blood cell counts in her amniotic fluid that she had an infection. An examination of the placenta, fetal lining and umbilical cord following the birth supported the infection. Han's tests of the amniotic fluid found the Bergeyella bacteria. ...

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