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Tag: "elevated" at biology news

Oceans more vulnerable to agricultural runoff than previously thought, study finds

...t concentrations in the oceans and sustains highly elevated rates of biological productivity." In the gulf, wind-driven upwellings regularly bring nitrogen and other nutrients from the seafloor to the surface, stimulating the rapid reproduction and growth of microscopic algae called phytoplankton. These alga...

Low oxygen likely made Great Dying worse, greatly delayed recovery

...history some 251 million years ago was preceded by elevated extinction rates before the main event and was fol...ygen levels was likely a major reason for both the elevated extinction rates and the very slow recovery. Earth's land at the time was still massed in a superco...

Scientists reveal the shape of a protein that helps retroviruses break into cells

...history some 251 million years ago was preceded by elevated extinction rates before the main event and was fol...ygen levels was likely a major reason for both the elevated extinction rates and the very slow recovery. Earth's land at the time was still massed in a superco...

Mouse with designer liver has enhanced glucose tolerance, insulin response

...ells. Upon stimulation with insulin, they found an elevated level of Akt/PkB kinase, an enzyme needed for insulin signaling, and elevated activity of IRS proteins. There was no activation of another enzyme, Erk, which is elevated in norma...

Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis

...arcinoma. NASH is one of the most common causes of elevated aminotransfereases in patients referred for evaluation to hepatologists. Obesity and type-2 diabetes are associated to NASH. Since the prevalence of these diseases is increasing, the prevalence of NASH is also expected to increase and therefore, this...

UCLA study assesses cost-effectiveness of Hepatitis B drugs

...he most common type of chronic hepatitis B -- with elevated liver enzymes but no liver cirrhosis. Investigators also took into consideration the two types of hepatitis B -- either e- antigen positive or e-antigen negative -- which require different treatment approaches. Hepatitis B is the most common serious...

Natural tumor suppressor in body discovered by UCSD medical researchers

...n cancer and gliobastoma human cell lines that had elevated Akt phosphorylation. Reintroduction of PHLPP into the cell lines caused a dramatic suppression of tumor growth. With additional laboratory tests, the team found that PHLPP stops tumor growth by deleting a specific phosphate molecule at a position cal...

Immune system's distress signal tells bacteria when to strike back

...ammatory bowel disease patients, for example, have elevated cytokines ?the chemical messengers that trigger an immune response ?in the bowel. "These could signal the bug," said Alverdy, "then the bug strikes back and then the inflammation process snowballs." Because the bacteria in this case are "normal flora...

Insulin pulses keep the liver lean

...cts of CEACAM1 might help to alleviate chronically elevated blood and liver lipids in patients with diabetes. Najjar et al.: "Insulin acutely decreases hepatic fatty acid synthase activity." Publishing in Cell Metabolism, Vol. 2, July 2005, pages 43-53. DOI 10.1016/j.cmet.2005.06.001. www.cellmetabolism.org ...

Elevated temperature enhances success of viral cancer therapy

...viral therapy after they have been incubated at an elevated temperature. The findings could have a significant...pharmacologically or by incubating the cells at an elevated temperature similar to that experienced by humans when they have a fever, the RNA export function wa...

Penguin chicks exposed to human visitors experience spike in stress hormone

...t 75 days old. None of the chicks demonstrated an elevated baseline corticosterone level. But 30 minutes and ...ker said. But it is unclear what later effects the elevated stress hormones might have. "We don't know yet what it means ?it might mean nothing, but it will ta...

Physical and functional interaction of key cell growth molecules linked to cancer

...side the cell. EGFR is often present at abnormally elevated levels in human cancer cells. Increased EGFR activ...f inducible nitric oxide synthase (iNOS). Although elevated iNOS is also a key characteristic of many human malignancies, there has previously been no direct co...

Study identifies gene in mice that may control risk-taking behavior in humans

...t a fear response in normal mice. They used a maze elevated 40 centimeters above a tabletop where mice had the option to walk along narrow, unprotected walkways or arms with protective walls. Half of the time the neuroD2-deficient mice chose the unprotected arms, whereas the normal mice almost always chose th...

Engineered skin offers clues to melanoma development

...oma. The scientists also investigated the role of elevated telomerase activity. In combination with other cancer genes, hTERT, the active protein in the enzyme telomerase, caused progressively invasive melanoma. In contrast, melanocytes that did not receive hTERT remained in an early stage of benign growth. ...

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

...oma. The scientists also investigated the role of elevated telomerase activity. In combination with other cancer genes, hTERT, the active protein in the enzyme telomerase, caused progressively invasive melanoma. In contrast, melanocytes that did not receive hTERT remained in an early stage of benign growth. ...

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

...oma. The scientists also investigated the role of elevated telomerase activity. In combination with other cancer genes, hTERT, the active protein in the enzyme telomerase, caused progressively invasive melanoma. In contrast, melanocytes that did not receive hTERT remained in an early stage of benign growth. ...

Squeezing out dune plants

...e plant populations no longer provided windblocks, elevated dune structures, or added to the sand and soil fertility. On Galveston Island, "the loss of such species is already occurring, where sea oats (Uniola paniculata) have disappeared due to a combination of human-induced disturbance and climate change,...

U-M researchers identify new blood test for prostate cancer

...o PSA. A physician might suggest a patient with an elevated PSA have this test before a biopsy to better determine whether it's a cancerous or benign condition. In the future, I think this could replace PSA," says lead study author Arul Chinnaiyan, M.D., Ph.D., the S.P. Hicks Collegiate Professor of Pathology...

Life-extending protein keeps blood sugar in check

...ions, when glucose levels are lower, the mice with elevated Sirt1 appear normal," Imai added. "This is good news, suggesting that therapies designed to manipulate the amount of Sirt1 might improve insulin response in those with type 2 diabetes without causing other problems." Pancreatic b cells have a highly...

Sea Ice May Be on Increase in the Antarctic

...ions, when glucose levels are lower, the mice with elevated Sirt1 appear normal," Imai added. "This is good news, suggesting that therapies designed to manipulate the amount of Sirt1 might improve insulin response in those with type 2 diabetes without causing other problems." Pancreatic b cells have a highly...

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