Driver of anthrax toxicity could lead to late-stage therapy
...utated cells for resistance to anthrax toxin in an effort to identify host genes that have important roles in infection, with the hope of finding possible new targets for therapies aimed at the host instead of the bacteria. The method allows for the identification of required host cell genes without pre-con...Climate change: The rice genome to the rescue
...em. The new knowledge generated by the sequencing effort is allowing scientists to both develop new rice va...$2 million of its own research funds as part of an effort to raise $20?5 million for a major five-year project to mitigate the effects of climate change on ri...Underdogs in the understory: Study suggests nature favors rarer trees
...alyzing and interpreting the data. "After all the effort that went into the analyses, it was neat to see that results from such different forests were so similar," Muller-Landau said. The study was conducted on seven undisturbed forest plots, or "tropical forest observatories," maintained and studied by ...'Virus chip' detects new virus in prostate tumors
...simultaneously. The study is part of an on-going effort launched two years ago by DeRisi and Ganem at UCSF, using the chip, or microarray, to search for new viruses associated with a wide range of human disease. So far, the chip has been used to search for novel viruses in about 300 cases of respiratory ...Whole-genome study at Johns Hopkins reveals a new gene associated with abnormal heart rhythm
...ibrillators in those with the highest risk. In an effort to identify risk factors with a genetic foundation, the researchers took the unconventional approach of starting from scratch and not looking at genes already known or suspected to be involved in heart rhythm. "Studying individual genes is not goin...Stem cells from muscles can repair cartilage
...ically engineered with a therapeutic protein in an effort to repair articular cartilage defects in rats. Led by Johnny Huard, PhD, director of the Growth and Development Laboratory at Children's Hospital of Pittsburgh and an associate professor in the departments of Orthopaedic Surgery and Molecular Geneti...Birth defects: 8 million annually worldwide
...s in the early 1960s, when it began its systematic effort to strengthen medical genetics services for the ca...d an essential addition to the extensive worldwide effort to reduce infant and child mortality to meet one of the United Nations Millennium Development Goals ...Overfishing in inland waters reduces biodiversity and threatens health
...ng. One leads to marked declines in catch per unit effort and size of individuals captured. The second type is characterized by sequential declines of species and depletion of individuals and species of large size, especially piscivores. These types are illustrated by case studies of fish declines in Austr...Setting the standard for computer models of life
Biologists are making a concerted effort to catalogue all the molecular components of living things, from the smallest molecules and ions to the genetic code. These 'parts lists' help them to build computer models that simulate living processes. By combining models of simple processes the...Superconducting magnet attracts molecular research
...f chemistry Tom Pochapsky, who spearheaded a group effort to bring the magnet to Brandeis. "It's a testament to Brandeis' strength in this area that the magnet is located on our campus and under our stewardship," noted Pochapsky. Brought in by crane and located at a site protected from large metal object...Wild birds help to create human flu vaccine
...es collected by WCS in international collaboration effort in Mongolia to be used in development of human pandemic influenza vaccineAvian influenza virus samples collected from wild birds in Mongolia by field veterinarians from the New York City-based Wildlife Conservation Society (WCS) have been selected by...NIH launches comprehensive effort to explore cancer genomics
...es of Health (NIH), today launched a comprehensive effort to accelerate our understanding of the molecular b...oject to determine the feasibility of a full-scale effort to systematically explore the universe of genomic changes involved in all types of human cancer. "...Bacteria that cause tooth decay able to survive without important biochemical pathway
... to result in 51 million lost school hours. In an effort to understand how best to combat the tooth-decaying properties of S. mutans, Brady and her team set out to learn how the organism was able to survive its own acid. To find out, the researchers tinkered with systematically turning off several genes, i...Seal rookeries could provide a reliable food source for endangered California condors, study finds
...nia Condor Recovery Program--a federally supported effort is to establish self-sustaining condor populations in the wild. Since 1992, program affiliates have released a total of about 130 captive-bred birds in wild areas of California, northern Mexico and near the Grand Canyon in Arizona. Newly released c...Engineered Stem Cells Show Promise For Sneaking Drugs Into The Brain
...is unable to cross the blood-brain barrier. In an effort to develop a less invasive strategy to effectively deliver the drug to the brain, Svendsen's team implanted the GDNF secreting cells into the brains of rats and elderly primates. The cells migrated within critical areas of the brain and produced the ...Lateral thinking produces first map of gene transmission
...ined the genomes of 144 species of bacteria, in an effort to map how genes are shared between bacteria. The study highlights lateral genetic transfer ?a process where genes are transferred between organisms that aren't directly related. The map has traced the paths of lateral gene transfer, from the bac...ORNL leading effort to help harness power of Shewanella
...participating laboratories, Uberbacher said. This effort could have a dramatic impact on the bioremediation mission involving approximately 2 trillion gallons of heavy metal contaminated groundwater and 75 million cubic meters of soil and subsurface sediment at various DOE and other sites around the nation...Why we give: New study finds evidence of generosity among our early human ancestors
...der or cheater in exchange relations." A rigorous effort to quantify the extent and magnitude of different ...tat, while more forgiving forms emphasize the work effort or relative contributions of others. Gurven examined food exchanges in two small-scale, non-market s...Molecular research suggest shift needed in how some drugs are created
... adapter molecule known as Tube, there has been an effort to target the similar IRAK-4 molecule in mammals, said Satish K. Nair, a U. of I. professor of biochemistry. The Pelle-Tube complex plays a crucial role in the innate immune response of fruit flies to fungal infection. IRAK-4 plays a similar role in...Software might revolutionize glucose monitoring in critically ill patients
...s incritically ill patients, saves nurses time and effort and is moreefficient than the paper-based method currently used in manyintensive care units (ICUs). Monitoring blood glucose levels isnecessary to avoid stress hyperglycemia, an insulin resistancecondition that causes glucose levels to go up and has ...