UQ scientists break new ground in fight against infection & chronic disease
...immune system responds to an infection in the most efficient and rapid way possible. "In some situations, this clever time-saving device could be a life-saver." Professor Stow said the study also looked at why having a "hair-trigger" immune response is a dangerous thing. She said these chemical messenger...Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
...hat a type of AAV, known as AAV-8, is particularly efficient at penetrating the capillary barrier, making it a good candidate for whole-body gene delivery. In this study, they tested AAV-8 in an animal model of human muscular dystrophy called limb girdle muscular dystrophy, or LGMD. In human LGMD, defects in a...Plants reveal a secret and bring researchers nearer a cleaner future
...ants and contribute to the efforts to produce more efficient solar cells for our needs". ...HIV inserts into human genome using a DNA-associated protein
...of human cells. These units are sites that lead to efficient expression of the viral genome. Most HIV-infected cells in a patient will have a very short life span, a day or less. "We surmise that this strategy helps the virus make hay while the sun is shining, as it were, producing lots of viral copies during ...Living anti-HIV gel shows early promise
...rough sexual activity, could offer cost-effective, efficient and long-lasting protection against the virus. The team, led by Srinivas Rao, chief of laboratory animal medicine at the Vaccine Research Center of the US National Institute of Allergy and Infectious Diseases, published their findings last week (23 ...Zebrafish may hold key to improved cancer research
...nd out with other animal models." "This low cost, efficient research should speed up drug development, save many millions of dollars and help lead to new cancer therapies." Using zebrafish, OSU has extensively studied two groups of carcinogens, polyaromatic hydrocarbons, or PAHs, and nitrosamines. Both of the......picture of how the brain is organized into "smart" efficient networks, and researchers hope that details of this complex design might, one day, uncover the roots of such neurological diseases as schizophrenia. "We know already that schizophrenia is a problem with organization of inhibitory circuits of neurons......and metabolism of nitrate and urea, as well as the efficient uptake of ammonia. The co-operation of theoretically and experimentally-oriented researchers shed light on other questions. The bioinformatics experts were able to predict that Natronomonas pharaonis can by itself produce vitamins and amino acids. T...Scientists discover the molecular switch for nerve cells' insulating jelly rolls
...sulation around nerve cells that ensures swift and efficient communication in the nervous system. The study, published in the September 1, 2005, issue of the journal Neuron, may provide a new avenue for treating nervous system diseases such as multiple sclerosis, which are associated with damage to myelin. A ...Fruit fly research set to revolutionize study of birth defects
... a revelation to the researchers who view it as an efficient model for the initial testing of "rescue" therapies to try to prevent birth defects. Scientists can study the effect of the drug on the genes of as many as three generations of fruit flies in a month using readily available scientific tools, speeding...A new step towards an AIDS vaccine
...ereby DC function can be targeted in the design of efficient vaccines or immunotherapies for HIV. ...Why Christmas trees are not extinct
...suggests why conifers not only survive but thrive: efficient microscopic valves let water flow through conifers... if conifers might have gone extinct without their efficient type of water valve, "what this study shows is that without this valve, it would be 38 times harder ...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
...ter in Baton Rouge, were hoping to come up with an efficient means by which they could image, target and destro...n's lymphoma. The next step is to design a more efficient complex. "Right now we saturated the nanoparticle, and it may not be necessary to use that much of t...The shape of things to come: Morphology database going global
...ch comments made by other scientists - a quick and efficient way to communicate research results. "We're hoping to achieve a change in the way scientists work when they do research," Ronquist said. "That's one of the biggest challenges - changing habits. We need to convince scientists that this is a better wa...Scientists pinpoint inflammation gene
...ple have is the 'good form' of SEPS1 that is more efficient at perceiving and responding to cellular stress. The alternative, rarer variant weakens SEPS1 and puts it at a disadvantage in dealing with cellular stress." Blangero explained, "Basically, this rarer form of SEPS1 gives you a lazy cellular 'garbage...Do the Europeans turn ill sitting up so late?
... researchers from five countries, thus creating an efficient network where the special skills of each partner can be utilized. The network will provide funding for 24 doctoral and post-doctoral researchers.A high level research training program is created in cooperation with the European universities, graduat...Discovering the first steps in transcription-coupled repair
...ng blockages in transcription and in initiating an efficient method of repair; their results suggested a previo...ans that transcription-coupled repair is much more efficient than other processes for resolving stalled transcription, since it can operate with RNAPII still in ...Scientist uses form to explain function of key building blocks of life
...erent sequences to transport electrons in the most efficient manner possible," Markley explains. "Different mechanisms have been put forward to explain this, and we wanted to understand how the proteins evolved to have different electron affinities." Markley and his team used nuclear magnetic resonance spect...How E. coli bacterium generates simplicity from complexity
...rich organic molecules. E. coli must also have an efficient way to eliminate waste products. It, like all living things, generates energy in a process that involves the removal of electrons from food molecules and attaching them to acceptor molecules. For aerobic organisms, the final electron acceptor is usua......ls are found throughout the body and are extremely efficient at alerting the immune system to the presence of pathogens and other foreign materials. Langerhans cells are dendritic cells in the skin. Skin is an important barrier to infection and it has been generally assumed that the Langerhans cells only serve...