effectively 2 6

Tag: "effectively" at biology news

Unique dual target specificity of kinase inhibitor key for success against cancer

...nase inhibitors must display a broad reactivity to effectively attenuate the complex signaling pathways involved in malignant transformation and to thwart to the ability of cancer cells to adapt to stress. Lipid kinases belonging to the PI3 kinase family, made up of different isoforms, promote cell growth and ...

Brain-computer link lets paralyzed patients convert thoughts into actions

...to activate limb muscles with these brain signals, effectively restoring brain-to-muscle control via a physical nervous system." "Our researchers initiated the clinical trial with the hope of being able to develop a non-obtrusive system that would one day provide more freedom to those with severe paralysis," ...

Scientists reverse evolution

...mbining critical portions of Hoxa1 and Hoxb1, they effectively recreated a gene with the function that the original Hox1 performed more than 530 million years ago. The result: A mouse with a disabled Hoxb1 gene still was able to move eyelids, whiskers and ears because the reconstructed gene made up for the lo...

Salk and Stanford teams join forces to reveal two paths of neurodegeneration

...et cells. Axon pieces that went astray degenerate, effectively being "pruned" back. Similarly, when axons are forcibly severed or seriously injured by disease in adults, they die and are removed by degeneration. Scientists have speculated that the same molecular shears used to trim axon branches in injured adu...

HIV-1's high virulence might be an accident of evolution

...If you could somehow dampen the response, it might effectively convert the condition to the more chronic, asymptomatic infection seen in monkeys." Further studies by the team will examine whether SIVs carrying Nef genes artificially made incapable of limiting T cell activation might become more pathogenic in th...

Defense peptide found in primates may block some human HIV transmissions

...versity of Central Florida researchers believe can effectively block the HIV-1 virus from entering and infecting blood cells. HIV-1 often mutates quickly to overcome antiviral compounds designed to prevent infections. But a research team led by Associate Professor Alexander Cole of UCF's Burnett College of Bio...

Genetic snooze button governs timing of spring flowers

... prolonged cold triggered a molecular process that effectively silenced the genes that repress flowering. Another processes known as bud dormancy, which is similar to vernalization, occurs in many plants that grow in temperate climates. "Bud dormancy is not broken until the plant has 'counted' a sufficient num...

Gold nanoparticles could improve antisense cancer drugs

...d can bind to the target messenger RNA (mRNA) more effectively than DNA that is not attached to a nanoparticle surface (as in commercial agents). When compared to antisense DNA complexed with commercial agents such as Lipofectamine and Cytofectin, the antisense nanoparticles were more effective in gene knockdow...

Experimental RNA-based drug kills prostate cancer cells effectively and safely

... containing cancer cells. They found that the drug effectively bound to prostate cancer cells, entered them and shut off production of the target protein, PLK1. The researchers then moved into mouse experiments. They injected the drug directly into the mice's prostate tumors, administering one injection every ...

A dichotomy in migration patterns found for sea turtles in east Atlantic

...th coastal and oceanic waters--will be required to effectively conserve these animals. The findings are reported by Brendan Godley and colleagues at the Marine Turtle Research Group at the University of Exeter in Cornwall, Michael Coyne of the Marine Geospatial Ecology Lab at Duke University, and other members...

A new tool against brain disease

...rus, a live virus vaccine against smallpox that is effectively cleared by the immune system. According to Walker, those findings indicate that activation of the PD-1 pathway occurs during the immune system's general response to viral infection. In test tube studies, the researchers showed that higher PD-1 ...

How HIV 'exhausts' killer T cells

...rus, a live virus vaccine against smallpox that is effectively cleared by the immune system. According to Walker, those findings indicate that activation of the PD-1 pathway occurs during the immune system's general response to viral infection. In test tube studies, the researchers showed that higher PD-1 ...

Sandia work launched on space shuttle shows live cells influence growth of nanostructures

... require no upkeep, yet sense and then communicate effectively with each other and their external environment," says former UNM graduate student and Sandia consultant Helen Baca, lead author on the paper. Baca was advised by Sandia Fellow and UNM professor of chemical engineering, molecular genetics & microb...

Scientists stop autoimmune disease without shutting off immune system

...pecific events in the cell could enable us to more effectively and safely treat patients." Rubenstein has previously shown an enzyme called p38 is part of the mechanism by which pemphigus vulgaris autoantibodies cause damage. Autoantibodies are immune-system cells that attack the body's own tissues. In a ...

First surveys of Tanzanian mountains reveal 160+ animal species, including new & endemic

...imited forestry department staff with tiny budgets effectively manage the forest reserves. The Rubeho Mountains are part of the Eastern Arc Mountain range in eastern Tanzania and located north of the city of Morogoro. Its forests are often covered in a blanket of mist during the night and help collect water for...

Finding a better way to make biodiesel

...y were also hoping to find technologies that would effectively make biodiesel out of raw materials such as used restaurant oils and animal fats ?materials that are much cheaper than soy oil, but also contain free fatty acids that can't be converted to biodiesel by current production methods. Lin has developed ...

Queensland scientists identify molecule that links both sides of the brain

...itical for the transmission of sensory information effectively throughout the adult brain." These findings are expected to have long-term implications for development of treatments for several forms of mental impairment and epilepsy. A QBI-led scientific paper outlining functions of the Ryk receptor molecule...

A more powerful and efficient engine for rice: the C3-C4 challenge

...s, C4 plants--such as maize--use solar energy more effectively for growth. Dr. Sheehy compared the potential impact of successfully transforming rice from a C3 to a C4 plant as even greater than the production of the semidwarf rice plants that sparked the Green Revolution. "If we can successfully develop a C4 ...

Malaria, potato famine pathogen share surprising trait

...Results showed that malaria proteins could just as effectively enter and infect a cell when it contained the P. infestans leader sequence instead of its own. "Our findings show that very distinct microbes can share similar strategies for delivering toxic proteins to their targets," Kamoun said. About a year an...

In-home sensors spot dementia signs in elderly

...tting of an elder's home, researchers hope to more effectively identify when elders are starting to have trouble. Hayes and colleagues in the OHSU Oregon Center for Aging & Technology - ORCATECH - used an unobtrusive "activity assessment system" to continuously measure in-home walking speed and overall act...

1 2 3 4 5 6 7 8 9 10