Most widely used organic pesticide requires help to kill
...es encoding the (Bt) toxins could be deployed more effectively in transgenic crops by exploiting the role of insect-borne bacteria that enhance insecticidal activity," the Wisconsin team writes in its PNAS report. What's more, the insight that gut microbes mediate the effects of bacterial toxins could have app...Complexity constrains evolution of human brain genes
... "We would expect positive selection to work most effectively on tissue-specific genes, where there would be fewer conflicting requirements," says Wu. "For example, genes expressed only in male reproductive tissues have evolved very rapidly." Brains, however, "are intriguing in this respect," Wu says. Genes...Mayo Clinic collaboration mining of ancient herbal text leads to potential new anti-bacterial drug
...arly results show that extracts from the Atun tree effectively control bacteria that can cause diarrhea, as claimed by naturalist Georg Eberhard Rumpf, circa 1650. He documented his traditional healing methods in the book Ambonese Herbal. The Mayo Clinic-led team's report appears in the Dec. 23 edition of The B...New finding points way to foiling anthrax's tricks
... the human immune protein, binds bacillibactin and effectively sidelines it, the researchers found. Apparently, anthrax fielded a second "stealth" iron scavenger, petrobactin, to get around the human defense against the first scavenger. Petrobactin is not bound by siderocalin. As far as is known, the human im...UGA scientists engineer root-knot nematode resistance
...ique called RNA interference, the researchers have effectively turned the nematode's biology against itself. They genetically modified Arabidopsis, a model plant, to produce double-stranded RNA to knock out the specific parasitism gene in the nematode when it feeds on the plant roots. This knocked out the paras...Genetic 'roadmap' charts links between drugs and human disease
...e is to connect each human disease with drugs that effectively treat it and to understand the molecular basis for such drugs' effects. To solve this problem systematically, the scientists described the effects of drugs and diseases in the common language of "genomic signatures," meaning the full complement of ge...Nice guys do finish first in lizards' evolutionary race
...partners aren't family. The tag-team approach does effectively thwart the orange-throat bullies, albeit at a personal cost. The term "greenbeard" refers to an evolutionary term of a trait so obvious that others can recognize The greenbeard in this case, McAdam said, is more than just a blue throat. The mechanis...Control measures fail to stop spread of new H5N1 virus
...rs, which suggests that H5N1 viruses have not been effectively contained. The investigators also conducted genetic studies of 390 H5N1 viruses isolated from poultry in the current study (30 percent of the total found in southern China) and found that 68 percent were of the FL sublineage. The emergence of...Knowledge of dendritic cells branches out
...zed "police "within the body, it seems that DC are effectively organized as specialized squads that deal with specific problems ?just as a police force might have different departments to deal with armed robberies, homicides and fraud. These discoveries at WEHI have profoundly altered our understanding of this i......les to alternating vacuum and carbon dioxide. This effectively suffocates organisms because they require oxygen to live. Ethanol gas is also used to kill fungi and bacteria. The technique could replace the use of post harvest pesticides, and may complete the phasing out of ozone depleting methyl bromide. In 199...Bioengineered tissue implants regenerate damaged knee cartilage
Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol. The study, "Maturation of tissue engineered cartilage implanted in injured and osteoarthritic...New treatment for food poisoning
..., in spite of it reaching the infection sites more effectively than other antibiotics. Professor Vazquez-Boland said: "Our results illustrate that antibiotic resistance in the laboratory does not always mean that the drug will not work in the infected patient. This work brings some optimism to the highly worryi...New study shows antibiotic may protect the heart
... the antibiotic's antigrowth properties, rapamycin effectively reduces coronary restonosis, the abnormal narrowing of a blood vessel. In coronary angioplasty, stents coated with rapamycin are implanted to reduce the risk of restonosis. "A significant clinical question will be whether or not rapamycin coated st...In drug design, a loose fit may be best bet
...ed, with certain analogs performing up to twice as effectively as TRH. As to why this would be the case, the researchers suggest that a loose connection between hormone and GPCR may allow a hormone to repetitively dock to and undock from its associated GPCR, activating a succession of G-proteins, and firing sign...Loosen up, DNA: Leukemia gene changes genetic packaging
...of jail so he can make more mischief. Behind bars, effectively inactive and silenced, the hoodlum ?in this case, a cancer-causing gene causing cells to grow out of control ?is not dangerous. When JAK/STAT frees the scofflaw, it's free to then meet up with its molecular buddies and wreak havoc on the body. It w...Researchers appeal for new regulations to save coral reefs from live fish trade
...s; an estimated 20% of the world's reefs have been effectively destroyed with no immediate prospects of recovery, 24% are under imminent risk of collapse and 26% are under longer term threat of collapse. The scientists argue in their letters that multilevel action, from local to international, is needed to est...Experimental vaccine protects lab animals against several strains of H5N1
...ting that two doses of vaccine will be required to effectively protect against an H5N1 flu strain. In an accompanying editorial, Alan W. Hampson, MSc, of the Australian Influenza Specialist Group, noted that the successful use of a genetically modified whole-virus vaccine that produced protective antibodies aga...3-D model reveals secrets of metastasis
...onal assays for metastasis-inhibiting drugs do not effectively predict their effects in tissue," says Lauffenburger, who is director of MITâ?super>TM s Biological Engineering Division. He believes pharmaceutical companies will eventually use three-dimensional assays, accompanied by appropriate computational ...Snakes' virtual glasses, leopard spots and all-optical transistors
...ssing relative rankings of students in a class, C) effectively eliminate student complaints about grading fairness, D) all of the above. (Answer: D)......articles such as bacteria and viruses. This design effectively persuades the cells to behave collectively the way they do in a fully functioning liver. The scientists write in their paper that in their experiments the Smart Petri Dish was able to detect changes in the cells exposed to toxins "before traditional...