Natural protein stops deadly human brain cancer in mice
...ohns Hopkins and from the University of Milan have effectively proven that they can inhibit lethal human brain cancers in mice using a protein that selectively induces positive changes in the activity of cells that behave like cancer stem cells. The report is published this week in Nature. The most common type ...Sensory feedback during speech: The brain attunes to more than just sound
...hed by Cell Press. When we speak, our ability to effectively produce words is dependent not only on auditory feedback signals to the brain, but also on so-called somatosensory information that informs the brain of the relative positioning of different parts of the body--a process known as proprioception. Cues ...Novel vaccine shows promise against early-stage breast cancer
...dent that targeted treatment with this vaccine may effectively fight not only DCIS, but may extend to prevention of breast cancer entirely." According to the American Cancer Society, approximately 200,000 women will be diagnosed with breast cancer in the U.S. in 2006, though thanks to new options for patients,...Supercomputing equipment to advance the frontiers of computational biology
...essful, these simulations must run efficiently and effectively on the latest generation of high-performance computing equipment. The project will help researchers develop critical computational biology tools that operate on the Blue Gene system, with the goal of making these available to a broad community of use...Detailed 3-D image catches a key regulator of neural stem cell differentiation in action
...tes by phosphatases like Scp1 turns out the light, effectively stopping RNA polymerase in its tracks. Noel and postdoctoral fellow Yan Zhang, Ph.D, analyzed the crystal structure of Scp1 and RNA polymerase together and obtained a 3-dimensional image showing how Scp1 hangs onto the seven amino acid residues r......ers from the original by about 10 percent, but can effectively infect primate cells and be used to test potential therapies. "If we can make this virus work in animals the way it works in tissue culture, it will likely change the way that AIDS vaccine and therapeutics research is done," Bieniasz says....Developing uses for sugar-cane bagasse: Biotechnology applied to the paper industry
...accase, from a culture of a filamentous fungus and effectively recycles the sugar-cane bagasse. Its principle lies in the specific metabolic characteristics of this fungus, Pycnoporus cinnabarinus, which produces laccase naturally. This enzyme breaks down the lignin in the fibres of bagasse used as substrate in ...Replacing insulin is top-ranked breakthrough foreseen for health in developing world
...s applications of regenerative medicine that could effectively improve health in developing countries; Assesses the feasibility of building developing countries' capacity in regenerative medicine, and Offers recommendations for developed and developing countries alike. An international panel of experts w...New research to cut animal testing
...oped techniques using cultured human cells to more effectively weed out cancer-causing compounds. "The current pre-animal tests that are used are highly sensitive and so most carcinogens are identified," said Dr Walmsley, who is based in the Faculty of Life Sciences. "Unfortunately, such tests have poor spe...The first tree genome is published: Poplar holds promise as renewable bioenergy resource
...arbon removal from the air by producing trees that effectively shuttle and store more carbon below ground in their roots and the soil. Moreover, bioenergy crops re-absorb carbon dioxide emitted when biofuels are consumed, creating a cycle that is essentially carbon neutral." Poplar's extraordinarily rapid growt...Research suggests beta agonists may alter the immune system
.... They found that the beta-agonists were unable to effectively stimulate the enzyme protein kinase A (PKA). Other molecules similar to beta-agonists that were able to strongly activate PKA also inhibited the ability of type 2 T cells to proliferate and survive. Penn said this finding could influence future drug ...... conservation implications of this study show that effectively protecting reserves to maintain high prey densities is a key pillar in an overall strategy for the conservation of tigers." The research team, which included Dr. Karanth and Dr. Jim Nichols from USGS, used remote cameras to identify individual tig...Boston University biomedical engineers win major grant for pursuit of the '$1,000 Genome'
...abling doctors to diagnose and treat patients more effectively based on their individual genetic profiles. ...Two-faced protein can stop metastasis or promote it, researchers say
...ncreases expression of mesenchymal cadherins, thus effectively loosening the anchors that keep the cell bound to its neighbors. Cancer, unfortunately, has adopted this strategy in order to spread, Anastasiadis says. "When the function of E-cadherin is lost in a cell, it can break free from its neighbors and t...Biofuel cells without the bio cells
... seal made by the protein coating on the electrode effectively acts in place of the membrane. ...Therapeutic role found for carbon monoxide
...ent exposures of one hour per day, CO gas might be effectively used as a therapy to treat PAH in a clinical setti...s thicken to the point that blood can no longer be effectively pumped through them, resulting in serious cardiopulmonary complications and in many cases, heart att...Perceived facial similarity in children is an estimate of kin recognition
Perceived facial similarity of children is effectively an estimate of the probability that two children are close genetic relatives according to a new study recently published in Journal of Vision, an online, free access publication of the Association for Research in Vision and Ophthalmology (ARVO). Pa...Researchers map spread of pathogens in the human body
...eld to devise more targeted treatments and to more effectively manage antibiotic drug resistance. In the past, similar investigations have been hampered by the difficulty of identifying and observing directly the infection process within live tissues. For this study, the Cambridge researchers used advanced...Cancer stem cells linked to radiation resistance
... researchers said, leads cancer stem cells to more effectively repair DNA damage and thus render the cells less likely to die as a result of the treatment. In another set of experiments, the researchers treated both the test animals and the cell cultures with a drug, called debromohymenialdisine, which is kno......e, the development of anti-retroviral therapy that effectively targets all sources of HIV, including the testis, is gravely needed. The use of this testis culture system may allow assessment of new anti-retroviral drugs that target HIV in the testis. ...