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Tag: "effectively" at biology news

Bypassing eggs, flu vaccine grown in insect cells shows promise

...e shown that an experimental vaccine appears to be effectively only at high doses. The experimental vaccine differs from approved vaccines in another way as well. The experimental vaccine focuses on a portion of the flu virus known as the hemagglutinin, which the virus uses to attach to blood cells. Unlike co...

Hybrid molecule causes cancer cells to self-destruct

...ndered by the high doses of the compound needed to effectively eradicate cancer. To get around this problem, scientists have tried to make butyrate more potent by modifying it or joining it to other compounds. Usually, the results have been disappointing because the molecular partner added to butyrate to improve...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...the mice doubled. (Neither treatment could work as effectively on its own. In fact, the effect was more than simply additive). This was a demonstration that stem cell efficacy could be enhanced even without the need for genetic engineering. (The drug, a glycosphingolipid biosynthesis inhibitor, is in a class of ...

Synthetic peptide targets latent papilloma virus infections

...ction of the peptide - works in the body, it would effectively stop the virus from spreading or generating warts, which can progress to cancer. "We're optimistic that this will work generally for many different genetic variants of human papilloma virus, though it's too early to say how many of the genotypes of...

A genetic 'gang of 4' drives spread of breast cancer

... tested whether cetuximab and celecoxib would work effectively in concert to reduce metastasis in mice. "We found that the combination of these two inhibitory drugs was effective, even though the drugs individually were not very effective," said Massagué. "This really nailed the case that if we can inactivate ...

New protein inhibitor impedes growth of cancerous cells

...rs have been identified as acting specifically and effectively against one particular cell-division kinase, known...nhibitor of Plk1, and show that BI 2536 can indeed effectively halt the growth of cancerous cells, both in cell culture and in an animal model for human tumor grow...

Scientists discover how body fights to control spread of cancer

...these sites. If caught early these tumours can be effectively removed surgically. However, when the cancer cells have invaded the blood, the effectiveness of surgery is reduced. Cancerous cells that have entered the blood, however, are still prevented from causing further disease by the protective shield of ...

Manipulating nature: Scientists query wildlife birth-control method

...ns. His second concern is that the technique is effectively a form of genetic engineering: "Immunocontraception alters the gene pool of the targeted species because those animals who are unresponsive are genetically unusual individuals," he says. "The job of the immunological system is to combat disease-c...

Scientists use nanoparticle to discover disease-causing proteins

...ry small sample amounts so sensitive that we can't effectively use existing technologies to study them," Tao said. "In addition, to study a specific protein and its function, we want to preserve its natural environment and see where two molecules meet and what the interaction is when they bind. "Taking small ...

Scientists find new genes for Crohn's disease

...suspected: that an individual's ability to respond effectively to harmful microbes influences his or her susceptibility to the disease. "We propose that genetic variation in the ATG16L1 gene leads to alterations in how the body uses autophagy and therefore may result in increased persistence of [toxic] cellul...

Scientists find method to pick noncompetitive animals, improve production

... possible to design selective breeding programs to effectively reduce competitive interactions in livestock, he said. The method also aids in predicting how social interactions impact the natural evolution of species. Muir and his colleagues write about the tool and its effectiveness in two papers published i...

Scientists find potential 'off-switch' for HIV virus

...ween p300 and SirT1 comprises the resistor and can effectively keep the virus in its dormant phase. "SirT1 reduces the strength of the signal to replicate," Weinberger said. "It may prove to be the key part of the resistor in the circuit, as our mathematical models are strongly suggesting." Not all the mo...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...h Tykerb." Tykerb is an enzyme inhibitor that effectively blocks two cell receptors, ERBB2 and EGFR, from re...r signals. By blocking these signals, Tykerb could effectively shut down the growth of solid tumors, such as those found in breast, lung and head and neck cancer. ...

Cheaper, better disease treatments expected from faster approach to developing antibodies

...in blocks the protein from doing harm in the body, effectively short-cutting a disease process. Georgiou, who holds the Cockrell Family Regents Chair in Engineering #9, and Chemistry and Biochemistry Professor Brent Iverson, the Warren J. and Viola Mae Raymer Professor and Distinguished Teaching Professor, p...

QUT scientists on the way to sifting out a cure for HIV

...high filtration flux or flow, and at the same time effectively filter out unwanted particles or viruses. He said another failing of current membranes was they often formed pin-holes and cracks during the fabrication process, resulting in wasted membranes. "With this in mind we have introduced radical chang...

Lab research may one day lead to cancer treatment using patient's own immune cells

...l research will help researchers learn how to most effectively select and obtain the T cells for this form of therapy. In future use with humans, the cells would be grown in the cell processing facility located in the Iris S. and Bert L. Wolstein Research Building, which opened in 2003. The activated T cells w...

Discovery of an HIV inhibitor in human blood points to new drug class

...inpointed a natural ingredient of human blood that effectively blocks HIV-1, the virus predominantly responsible for human AIDS, from infecting immune cells and multiplying. The virus blocker might play a role in the progression of HIV to full-blown AIDS and—because it works in a different way than existing anti...

Brain networks strengthened by closing ion channels

...longer flow into the cell, and thus the network is effectively disconnected. Arnsten said inhibiting cAMP closes the channels and allows the network to reconnect. The study also found alpha-2A adrenergic receptors near the channels that inhibit the production of cAMP and allow the information to pass through ...

RNAi shows promise in gene therapy, Stanford researcher says

...ique. Since then he has used RNAi gene therapy to effectively shut down the viruses that cause hepatitis and HI...ein-coding message removed, the gene's message is effectively destroyed. When used as gene therapy, RNAi turns off genes that are overactive in such diseases as...

Neural bottleneck found that thwarts multi-tasking

...offers neurological evidence that the brain cannot effectively do two things at once. People think if they are using a headset with their cell phone while driving they are safe, but they're not because they are still doing two cognitively demanding tasks at once." Identifying the information bottleneck respon...

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