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Tag: "effectively" at biology news

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model

...dies also showed that the delivered genes had been effectively incorporated into the target nerve cells. According to Dr. Glorioso, HSV delivery of GDNF or neurturin presents a potentially important new approach for the treatment of ED. "Because the herpes virus persists in the nerve cell for as long as it is...

Snoring in children might be an allergic type disease

...a hopefully contribute to a clinician’s ability to effectively spot snoring in pre-school children in order to identify potentially more serious obstructive sleep apnoea.” ...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...insight into how future drugs might be designed to effectively kill the parasite," said Paul Roepe, Ph.D., a professor in the Department of Biochemistry and Cellular & Molecular Biology as well as the Department of Chemistry. Any animal with red blood cells can develop malaria, which is caused by a singl...

Newly found sensing system enables certain bacteria to resist human immune defenses

...aps must be present for the system to function and effectively protect bacteria from AMPs. “We are aware that for gram-negative bacteria, PhoP/PhoQ has been called a premier target for antimicrobial drug discovery, but little corresponding work has been done with gram-positive bacteria,” Dr. Otto says. “Our g...

U-M researchers discover gene switched off in cancer can be turned on

...pular new drugs such as Herceptin and Gleevec more effectively treat cancer by targeting genetic mutations that express themselves in large amounts, causing cancer to develop. But cancers also arise because genes that control growth are turned off. While researchers can use these turned-off genes to identify or ...

Undergraduate research shows leaderless honeybee organizing

... mystery still remains regarding how bee societies effectively direct and coordinate complex operations without a...ll-unknown way initiate a string of behaviors that effectively manage complex group activities. “It is a real challenge to understand how bee colonies work, bu...

MU researchers to study the status of black bears in Missouri

... generate the data needed to better understand and effectively manage the black bear population.” Dave Hamilton, a resource scientist at the Missouri Department of Conservation, said he believes there are approximately 300 black bears in Missouri, but only a few females. This study will give the Missouri Dep...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

...ls. It can deliver diagnostic or therapeutic cargo effectively for a wide range of needs." Harmless strains of bacteria could be used as vehicles, harnessing bacteria's natural ability to penetrate cells and their nuclei, Bashir said. "For gene therapy, a big obstacle has been finding ways to transport the...

Ancient retrovirus sheds light on modern pandemic

...hers found that the human antiviral protein TRIM5a effectively neutralizes this extinct retrovirus, which never successfully fixed into the human genome. "However, while TRIM5a may have served humans well millions of years ago, the antiviral protein does not seem to be good at defending against any of the retr...

Focused ultrasound relieves fibroid symptoms in women

A noninvasive ultrasound procedure effectively shrinks uterine fibroids and significantly relieves fibroid-related symptoms in women, according to the results of a multicenter clinical trial reported in the June issue of the journal Radiology. Magnetic resonance-guided, focused ultrasound surgery...

Protein enables discovery of quantum effect in photosynthesis

..., in that vast areas of phase space can be sampled effectively to find the most efficient path for energy transfer. "We have a very detailed molecular structure of this protein and we understand the electronic properties of it very well, too," said Blankenship. "It's taught us a lot about how chlorophylls i...

Keeping the immune system from starting a 'food fight'

...t its suppression, the body might retain control," effectively unlinking chronic overeating and obesity from other symptoms of metabolic disease. He cautioned, however, that the realization of such a treatment strategy remains uncertain and would require years of continued investigation. Cells and organisms m...

LIAI scientists make important finding on cytomegalovirus transmission

... quickly, thus building the body’s ability to more effectively battle the virus. "We used this approach to tip the balance in favor of the T cells that would reduce the virus," he said. The scientists got a stronger result by blocking the IL-10 receptor. "It significantly reduced the virus load in all the a...

First demonstration of new hair follicle generation in an animal model

...ment for male-pattern baldness. If researchers can effectively control hair growth, then they could potentially find cures for people with hair and scalp disorders, such as scarring alopecia where the skin scars, and hair overgrowth....

No magic tomato? Study breaks link between lycopene and prostate cancer prevention

...ioxidant predominately found in tomatoes, does not effectively prevent prostate cancer. In fact, the researchers noted an association between beta-carotene, an antioxidant related to lycopene, and an increased risk for aggressive prostate cancer. According to the researchers, the study is one of the largest to...

Rapid response was crucial to containing the 1918 flu pandemic

...ntly, both studies showed that while interventions effectively mitigated the transmission of influenza virus in 1918, a critical factor in how much death rates were reduced was how soon the measures were put in place. Officials in St. Louis introduced a broad series of public health measures to contain the fl...

Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising

...d that the pulsed microjet system could be used to effectively deliver drugs for local and systemic applications without using needles. "The microjet system delivers precise doses into superficial skin layers, thereby mitigating pain," says Samir Mitragotri, a professor of chemical engineering at UCSB and a ...

Penn researchers show how nanocylinders deliver medicine better than nanospheres

...g cancer is treated, this discovery of how to more effectively deliver drugs to the body could also improve the treatment of such other illnesses as cardiovascular disease as well as other types of cancers. This discovery is also helping scientists understand why some viruses are so effective. "Cylindrical d...

New compound prevents alcoholic behavior, relapse in animals by blocking stress response

...gnals active during the brain’s response to stress effectively stops excessive drinking and prevents relapse. The new, synthetic compound, known as MTIP, also muted the anxiety that typically develops in rats experiencing the equivalent of a hangover. Such stress is linked with higher levels of a brain chemica...

Nanotextured implant materials: blending in, not fighting back

...lial cells quickly colonized the foreign surfaces, effectively camouflaging them and preventing smooth muscle cells from overgrowing the implants. Once the endothelial cells form a single, solid layer, they stop piling on and switch to producing the proteins collagen and elastin. In one experiment, published ...

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