Basic work on E. coli identifies two new keys to regulation of bacterial gene expression
...ts use model organisms because they are relatively easy to work with and because there is a vast amount of previous knowledge about them. They can then test whether their findings in model organisms hold true in other species, says Gourse, who studies a strain of E. coli that while harmless, is closely re...Sticky surfaces turn slippery with the flip of a molecular light switch
... a surface from sticky to slippery could now be as easy as flipping a molecular light switch. Researchers at Rensselaer Polytechnic Institute have created an "optically switchable" material that alters its surface characteristics when exposed to ultraviolet (UV) light. The new material, which is described...'Signature' of chromosome instability predicts cancer outcomes
...enior investigator. "We have achieved a relatively easy way to measure the level of chromosomal instability in a given tumor sample." The technique may help in the search for cancer drugs that reduce chromosomal instability -- an approach of increasing interest to researchers -- by making it possible to...Johns hopkins researchers find link between cell's energy use and genome health
...re single-celled organisms, they grow quickly, are easy to analyze in the lab, and contain many genes and biological processes present in other animals, including humans. For example, like all animal cells, yeast use sugar as an energy source. To harvest the energy contained in sugar, the yeast must co...Sandia work launched on space shuttle shows live cells influence growth of nanostructures
...ructures are cheap, extremely light and small, and easy to make, they could conceivably be attached to insects and their emanations read remotely by beams from unmanned aircraft. The method also makes it easier to prepare individual cells for laboratory investigation under microscopes. "Normally, to vis...Radiation-killed bacteria vaccine induces broad immune response in mice
...hemical-killed vaccines, while safe and relatively easy to produce, generally produce a less broad immune response than live, attenuated vaccines. Conversely, it can be difficult to create live, attenuated vaccines that safely preserve the pathogen's ability to trigger strong innate and adaptive immune re...Marine 'dead zone' off Oregon is spreading
... development of low-oxygen waters. It's not always easy to measure the biological impact of the dead zones, because many dead animals may be washed out to the deep sea. But researchers say that this year's event may ultimately be as severe as the first one in 2002, although it reflects slightly different ...Brittle prions are more infectious
...on," said Weissman. "The other key feature was how easy it was to break up the prion and create new seeds, and this propensity to seed could be an important determinant of the prion's physiological impact. And that is what we found experimentally -- that the slower growth of that conformation was more tha...UC San Diego biologists solve plant growth hormone enigma
...-a small plant favored by biologists because it is easy to manipulate genetically--Zhao's team inactivated combinations of the YUCCA genes and studied the effects of the inactivations on plant growth and development. "Plant biologists have wanted to do this experiment for a long time, but only recently h...Discovery may speed forest biotechnology
...to death. "From an evolutionary perspective, it's easy to understand why forest trees don't flower and produce seed and pollen earlier," Strauss said. "When they are young, the trees that survive need to focus their energy on growth and height in order to compete for sunlight with other trees, and only l...AIDS-related cognitive impairment exists in two separate forms
... array" test, which is designed to be low cost and easy to administer, appears to be a better predictor of...assay that can then be read automatically makes it easy for routine clinical use," she said. "The test has a lot of potential, but needs to be further studi...Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers
... array" test, which is designed to be low cost and easy to administer, appears to be a better predictor of...assay that can then be read automatically makes it easy for routine clinical use," she said. "The test has a lot of potential, but needs to be further studi...UCR researchers design chip that can improve citrus varieties
...dy traits pertinent to the citrus industry such as easy peeling, seedlessness, flavor components, pest and disease control, nutritional characteristics, and reproductive development. "The citrus array helps us quickly examine a certain trait in citrus," said Mikeal Roose , a professor of genetics in the...Computer scientist sorts out confusable drug names
...nies covet finding good, short drug names that are easy to remember, Kondrak noted, adding, "the FDA and other drug agencies need to balance this against confusing the names with existing ones--it's a serious problem." Kondrak co-authored a paper on this topic that was recently published in the journal A...Chocolate milk could be key to longer, healthier life
...itochondria. We hope to highlight an effective and easy way to maintain the protein content in muscles or at least replace old and damaged proteins with new ones." With funding assistance from the New Zealand Health Research Council, Dr Miller and PhD student Cheryl Murphy, asked a group of elderly kiwis...Nanopore method could revolutionize genome sequencing
...eter made from silicon nitride--a material that is easy to work with and commonly used in nanostructures--surrounded by two pairs of tiny gold electrodes. The electrodes would record the electrical current perpendicular to the DNA strand as the DNA passed through the pore. Because each DNA base is struc...Study fishes out new role for prostaglandins
...rafish, which develop quickly, are inexpensive and easy to manipulate, could actually aid in the discovery of new cancer drugs. "If you could use the zebrafish intelligently to screen for these drugs, it might really speed up the drug discovery process and give us some early clues about the effects we m...Common molecular 'signature' identified in solid tumors
... appeared to be non-functional. They may have been easy to overlook: miRNAs are usually only 22 or so nucleotides in length ?miniscule in size when compared to their cousins, messenger RNA, which can be several hundred to a thousand times that long. But several years ago, researchers studying roundworms...New weapon in battle against osteoporosis
...ope for women with a CB2 defect, too. First, it is easy to identify whether a woman is carrying the relevant mutation, so the results promise improved and faster diagnosis. Second, they have drawn attention to a previously unknown regulatory mechanism, making it a focus of osteoporosis research. Here lies......gain. But if you coil the hose orderly, then it is easy to use again. I think the virus does the same thing. The virus genome has to enter the capsid during the birth of the virus and then inject into the cell during infection. It has to come in and get out easily. The hub anchors the tail spikes, but is ...