Scientists discover stage at which an embryonic cell is fated to become a stem cell
...pulating epigenetic information in this protein in early mouse embryos can influence cell fate determination ...Ancient amphibians evolved a bite before migrating to dry land
...mparing the skull roofs of living fish to those of early amphibians and their fishy ancestors, we were able...e same cranial junctions in several fossils -- the early amphibian Acanthostega, its fishy ancestor Eusthenopteron, and the extinct terrestrial amphibian Pho...Protein overexpression at heart of heart failure
...he L-VDCC, based on gene expression changes, is an early step in a cascade ultimately induced in heart failure. This provides a rational framework for novel therapeutic intervention in heart failure. ...Elucidation of the genome for diabetics with DNA chips
...T2. Abnormalities in insulin secretion appear very early in the children of diabetic parents. These individuals become hyperglycaemic when they put on weight and are resistant to the insulin they produce. The team of Philippe Froguel was the first to identify a gene associated with DT2 ?that encoding gluco...Massey researchers induce cell death in leukemia
...-- as well as the emerging body of preclinical and early clinical data suggesting interactions between HDAC inhibitors and bortezomib in other tumor cell types, particularly hematologic malignancies -- is certainly of interest and warrants further investigation as a potential therapeutic strategy in CLL." ...UBC researchers reveal dwarf aquatic plants' hidden ancestry
...piecing together the details of the rapid rise and early diversification of flowering plants," says Graham....heritage makes us re-evaluate our understanding of early flowering-plant evolution. For botanists, this is like finding something you thought was a lizard is...Gene that makes people 'early to bed and early to rise' demystified
...nt "clock" gene made some people "early to bed and early to rise," a condition known as familial advanced s...ir bodies' natural alarm clocks get set to such an early wake-up time. In studies of mice carrying the human FASPS gene, the researchers found that the muta...Paleontologists discover new mammal from Mesozoic Era
...he journal Nature, provides first-hand evidence of early evolution of the mammalian middle ear--one of the ...by the National Science Foundation (NSF). "This early mammalian ear from China is a rosetta-stone type of discovery which reinforces the idea that develop...Researchers urge monitoring of bone health during chemotherapy
...ffect on bone metastasis in the experimental mice, early clinical trials in humans using G-CSF with chemotherapy have so far shown no adverse effects on survival and no increase in bone metastasis. In fact, breast-cancer patients undergoing dose-dense chemotherapy with G-CSF support tend to have a longer d...Post oak grasshoppers emerging
...grasshoppers become adults in late April, and from early May to mid-June the females lay their eggs in the soil. A female typically lays five to six eggs at a time in a pod, and will produce two to four pods over her lifetime. In the spring, when post oak leaves begin to emerge, the eggs hatch and the nymp...Prenatal cocaine's lasting cellular effects
...tion -- equivalent to the late first trimester and early second trimester in humans -- caused specific alterations in brain circuits that use the neurotransmitter dopamine. Additionally, these cocaine-exposed offspring showed attention problems as well as insensitivity to stimulants like amphetamine, sugge...Selective marker found to indicate aggressive form of breast cancer
...g breast cancers, this subtype is known to have an early age of onset and a very short time between treatment and relapse. It is more commonly detected during normal screening mammogram intervals than other screening subtypes, which likely reflects its aggressive nature. These important clinical correlati...Genes may determine success of hip replacement surgery
...wing surgery. Among those with symptoms, 91 had early signs of “aseptic loosening,?which describes a condition in which the artificial joint comes loose and the surrounding bone begins to dissolve. The other 71 patients had deep-seated infection, which occurs when the body is unable to control infection...Scientists find new genetic clue to cause of Alzheimer's disease
...dentified three genes, variants of which can cause early onset Alzheimer's, and one that increases risk for the late onset form. This discovery provides a completely new genetic clue about the late onset forms of this very complex disease. We are eager to investigate the role of this gene further." Scien...Global 'sunscreen' has likely thinned, report NASA scientists
...nning of Earth’s "sunscreen" of aerosols since the early 1990s could have given an extra push to the rise in global surface temperatures. The finding, published today in the journal Science, may lead to an improved understanding of recent climate change. In a related study published last week, scientists f...New research shows that flu is a trigger of heart attacks
...erosclerotic lesions in their coronary arteries in early childhood and these lesions grow over time. Inflammation plays a pivotal role in development and growth of these lesions. Most people in Western countries live with different stages of atherosclerosis and many will never show any clinical manifestati...40,000-year-old skull shows both modern human and Neandertal traits
...d colleagues in Europe compared the features of an early modern human cranium found in the Peºtera cu Oase ...await considerations of larger samples of European early modern humans and chronologically intervening specimens. But this fossil is a major addition to the...Mystery of fossilized trees is solved
...cular find, which has allowed us to recreate these early forest ecosystems. Branches from the trees would have fallen to the floor and decayed, providing a new food chain for the bugs living below. "This was also a significant moment in the history of the planet. The rise of the forests removed a lot of...Cheaper, better disease treatments expected from faster approach to developing antibodies
... off the production process. Based on the method's early success, Georgiou has begun a collaboration to identify antibodies to treat arthritis and asthma. In Georgiou's E-clonal antibody method, an antibody that is produced by an E. coli bacterium becomes tethered to one of its inner surfaces, or membr...Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find
... Injury Center have increased 60 percent since the early 1980's, but geriatric SCI admissions have increased more than 580 percent during that same time period, the researchers found. "This increase is likely a result of an aging population and propensity for these patients to have SCI with minor tra...