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Tag: "earlier" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...f puberty, as well as learn about KiSS-1, which in earlier rodent studies had been identified as a molecule that activates a signal receptor of GPR54, the researchers looked to the nonhuman primate, the only animal with a reproductive system in common with the human's. The onset of puberty becomes official ...

Wisconsin scientists grow critical nerve cells

... for a later stage of neuron development to a much earlier step in the process? The hunch paid off and turned out to be the final piece of the puzzle. The discovery, says Zhang, demonstrates that human stem cells do not necessarily differentiate in linear fashion, as scientists always believed. Rather, a s...

Association of herpesvirus with lung disorder questioned

...eir research using a design similar to that in the earlier study: a retrospective analysis of pathology speci... from unrelated patients. Like the authors of the earlier study, Katano and colleagues performed two types of tests in the tissue samples, one to detect an an...

Man and mouse share genome structures

...oints of active genes, as they and others had seen earlier in the yeast. Unexpectedly, they also found tags idling over regions near genes. The researchers think these sites have important regulatory functions, because the methylation patterns are similar in comparable portions of the mouse genome. Until now...

Spleen may be source of versatile stem cells

...ader therapeutic applications thansuggested by our earlier work."In 2001 Faustman's team found that a treatme...Late in 2003 they reported the mechanismbehind the earlier discovery: cells from the spleens of donor mice -intended to train the diabetic animals' immune syst...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...hould expand attention in colon cancer research to earlier events, situations present well before tumors appear," says the study's leader, Andrew Feinberg, M.D., M.P.H., professor of medicine and director of the Center for Epigenetics in Common Human Disease at Johns Hopkins. "In the mice with a double dose...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...res that portend poor outcomes may soon be treated earlier and more effectively," said Dr. Chiorazzi. "Once these new prognostic markers are clinically available to doctors, and after large-scale trials testing early intervention are completed, the 'watchful waiting' practice may be abandoned in many cases,...

Researchers Uncover Key Step In Manufacture of Memory Protein

...or mature brain-derived neurotrophic factor. In an earlier study, another team of NICHD researchers had shown that mBDNF is essential for the formation of long-term memory, the ability to remember things for longer than a day. “Understanding how BDNF is made may help us to better understand the learning pro...

Scientists detect probable genetic cause of some Parkinson's disease cases

...re there is no strongfamily history, could lead to earlier detection of Parkinson's disease.Further study of how this gene works also might help scientistsidentify new treatments."In addition to Dr. Singleton, the collaborative work was spearheaded byWilliam C. Nichols, Ph.D., of Cincinnati Children's Hospit...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

We ran a similar gene synthesis story earlier ;progress in this area is made in the UK, too. It'll open tons ofresearch avenue, speeding the slow (and tedious) process of genecloning, or gene modification (mutations, deletions, etc). Devices the size of a pager now have greater capabilities than...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...ound of the Discovery Dr. Badley's research group earlier discovered that protease inhibitors affect "pore function" of "channels" in a specific cell type they were studying. Pore function in channels permits the exchange of biochemical signals within and between cells. After hearing of a case of heart rhyt...

Scientists seek answers on what activates deadly anthrax spores

...Bill Boles, M.S., and Sumana Choudhury, M.S. Paige earlier received a $161,000 graduate fellowship from the Department of Homeland Security to support her research. ...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...fective treatment for Pompe disease. The Duke team earlier developed enzyme replacement therapy, in which a normal version of the faulty enzyme in those with the disease is infused weekly. In clinical trials of the replacement therapy, the infusions have already prolonged the lives of many babies with Pompe ...

Probing The Promise And Perils Of Nanoparticles

...entrations of these nanoparticles can be toxic. In earlier work, U-M researchers discovered that dendrimers p...ot damage membranes. Both Leroueil's work and the earlier research used model membranes to probe the effects of nanoparticles. Now, the research group is expl...

Researchers discover molecule that causes secondary stroke

...researchers called BOXes. Building on Dr. Clark's earlier studies in rats, the team measured each of the suspect agents in 12 hemorrhagic stroke patients. Within 10 days, four of the group suffered a secondary cerebral vasospasm. The same patients were also found to have elevated levels of bilirubin and sig...

Alcohol's effects on gene expression in the central nervous system

...ts of alcohol." # Microarray techniques confirmed earlier reports indicating that chronic alcohol exposure/withdrawal differentially alters gene expression in the prefrontal cortex of mice. More than 300 genes were found to be altered by acute alcohol treatment. "The prefrontal cortex is involved in motiva...

MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

... has succeeded in adapting andcreatively extending earlier developed techniques for stochasticallysimulating chemical reactions so that they can be used to study realcellular systems, where the huge numbers of potential species andreaction channels makes things very difficult."Computer simulations can be pow...

Scientists identify new model Of NK cell development

... lymph nodes also lacked NK cells. In addition, in earlier research in Caligiuri's laboratory, scientists had identified two distinct subsets of human NK cells (referred to as CD56 bright and CD56 dim cells) and they observed that the bright subset appeared much more frequently in lymph nodes than in bone ma...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...n the nuclei of these cells. Kaestner's group had earlier published research on a transcription factor called Foxl1 that is also expressed in the colon, but in a different layer of cells, adjacent to the epithelium, called the mesenchyme. They had seen that mice that are deficient for the Foxl1 protein show...

Falling ants glide back to trunk to avoid dangers of forest floor

... sheet standing in for the tree trunk. Yanoviak's earlier observations combined with the videotaped tests in Panama established that the ants basically reorient their bodies so their hind legs and abdomen point toward the tree, and use their head-up fall through the air to take them feet-first toward the tr...

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