Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses
... mitochondria, which are found in large numbers in each liver cell. When specialized receptor molecules detect viruses in the cell, they dock with the MAVS proteins, thereby triggering a sequence of signals ending with the production of interferon beta?a potent inhibitor of virus replication. Recent resea...Procedure predicts embryos most likely to result in pregnancy
...00 in-vitro fertilization procedures are performed each year in the United States. In 2002, 3.1 embryos on average were transferred in IVF cycles, but only 34.3 percent resulted in pregnancies. Of those successful pregnancies, 29 percent resulted in multiple births. These statistics remained unchanged wit...Ethanol vehicles pose a significant risk to human health, study finds
...lth Organization estimates that 800,000 people die each year from ozone and other chemicals in smog. ''In our study, E85 increased ozone-related mortalities in the United States by about 200 deaths per year compared to gasoline, with about 120 of those deaths occurring in Los Angeles,'' Jacobson said. ...Scientists create dual-modality microbeads to improve identification of disease biomarkers
...eads that are unique and can be distinguished from each other. It’s similar to bar-coding -- once you barcode the beads and put them in the urine or blood sample, you can remove them and decode what proteins or viruses have attached to individual beads based on their spectral signature," explained Sathe. ...Antivirals effectively curb influenza virus
...N2 or H1N1). The authors reviewed the effects of each antiviral on infectiousness and pathogenicity ?the... small and combined estimates from two studies for each drug were used in both instances. Furthermore, oseltamivir treatment of ill persons did not appear t...Custom-made cancer cell attacks
.... For example, in British Columbia they are losing each year forests the size of Rhode Island because of beetle infestation, because it is not cold enough in the winter to kill the beetles, and they are killing the forest.'' Achievable goals The president's target of 35 billion gallons of alternat...Scientists discover a new risk factor for Alzheimer's
...veral different Alzheimer's variants of SORL1, but each variant might have been associated with a different SNP pattern. That complexity would have obscured the SNP marker patterns that the researchers were tracking. The importance of this work is that it identifies a new player among the mechanisms ca...Cellulosic ethanol: Fuel of the future?
.... For example, in British Columbia they are losing each year forests the size of Rhode Island because of beetle infestation, because it is not cold enough in the winter to kill the beetles, and they are killing the forest.'' Achievable goals The president's target of 35 billion gallons of alternat...Researchers hot on the trail of brain cell degeneration
...ch will uncover more such factors interacting with each other. Investigating these will benefit new forms of treatment and advance research that aims to alleviate symptoms. The researchers behind the study hope that the results can be used in planning new targets for drugs to reduce the cell destruction s...Eating less salt could prevent cardiovascular disease
...mortality rate. This risk reduction was evident in each trial. To the authors knowledge this study is the first and only study of sufficient size and duration to assess the effects of a low salt diet on cardiovascular problems based on randomised trial data. It provides unique evidence that lowering sa...Penn researchers replace organ in adult mice using 'single-parent' stem cells
...owever, require two sets of chromosomes - one from each parent - to create a functioning embryo.According to McLaughlin, this is because mammalian embryos rely on a process called genomic imprinting, where cells will read certain genes from only one parent. Imprinting failures could lead to the death of ...Freeze! Scientists film proteins at work by freezing them at different states
...opriate ones by showing them the chemical bonds in each stage of the reaction. Once they had identified the right states, they studied the sample with synchrotron x-rays. “We expect this new methodology to be of use for many researchers in the field? Bourgeois explains. Filming certain proteins whilst ...Old dinosaur research leads to new honor
...eptiles and birds were just becoming separate from each other. It was an exciting time in history, about 270 million years ago ?it was between ice ages, just like the time we are living in now ?and I think my work has led to a greater understanding of what happened then." Reisz earned three degrees in ...UCLA scientists design masks to hide genetic mutations from cell
...e researchers designed a custom mask to camouflage each abnormal splice. The technique prevents the cell from seeing the genetic defects and restores splicing to the correct location in the gene. IMPACT: The laboratory findings suggest a powerful new approach for treating cancer and other diseases c...Gene study shows three distinct groups of chimpanzees
...nd eastern populations are more closely related to each other than they are to the western "subspecies." They also devised a simplified set of about 30 DNA markers that zookeepers or primatologists could use to determine the origins of a chimpanzee with uncertain heritage. "Finding such a marked d...Re-analysis of cigarettes confirms tobacco companies increased addictive nicotine 11 percent
... nicotine yield per cigarette averaged 1.6 percent each year, or about 11 percent over a seven-year period...icotine yields were increased in the cigarettes of each of the four major manufacturers and across all the major cigarette market categories (e.g. mentholat...Uganda's mountain gorillas increase in number
...unting trails and nests (gorillas construct a nest each night), researchers used genetic analyses as well, specifically because many of the groups were clustered in the same area of the park, which presented survey teams with the risk of double-counting the same individuals or groups. DNA analysis, howeve...Active ingredient in common Chinese herb shown to reduce hypertension
... ratio was significant relative to the vehicle for each concentration as well as for comparison between the two concentrations of tanshinone IIA. Conclusions As a result of the findings the researchers concluded that tanshinone IIA: (1) significantly reduced blood pressure in hamsters, (2) enhanc...Antibody signal may redirect inflammation to fuel cancer
...sses that because of the unique antibody makeup of each person, there is no evidence and no likelihood that periodic booster shots of the immunoglobulin antibody, or even blood transfusions from someone with precancerous tissue could trigger cancer progression in a recipient. ...New research may overturn conventional wisdom on drug-resistant tuberculosis
... killer diseases, claiming roughly 2 million lives each year. Drug-resistant TB is a growing problem worldwide. Most resistance is believed to derive from inefficient treatment, leading to mutations. This study found that 33 of 38 patients had a different strain of TB during tre...