Matrilin-3 gene discovered to prevent onset of osteoarthritis
... as skeletal disorders such as multiple epiphyseal dysplasia (MED), a disorder that begins in childhood and can include malformation of the hands, feet and knees and abnormal curvature of the spine. In this study, researchers knocked out matrilin-1 and -3 in mice in order to study their link to osteoarthriti...Key to acute lung injury lies in Ang2 protein
...ome who either went on to develop bronchopulmonary dysplasia or died. "Mice without Ang2 seemed to be protected against hyperoxia," said first author Vineet Bhandari, M.D., assistant professor of pediatrics at Yale School of Medicine. "This protein seems to be a mediator of cell death in the settings of hig...Temple University Hospital investigates treatment for cervical dysplasia
...0,000 women are diagnosed with high-grade cervical dysplasia each year, with roughly 10,000 cases progressing t...is being developed to offer patients with cervical dysplasia and healthcare providers an option to surgical intervention," explained Hernandez. "Qualified partic...