Researchers discover how bacteria sense their environments
... and heavy metals with great sensitivity, gain and dynamic range. Scientists are interested in developing synthetic systems with such sensing properties as well as engineering bacteria that respond to stimuli such as pollutants or explosives. Using a combination of X-ray crystallography to determine the str...ABCB6 is key to production of heme in hemoglobin
... and pulling them in. "We showed that there is a dynamic relationship between ABCB6 and the levels of heme and porphyrin that helps to regulate the production of heme," Schuetz said. The team found that the increase in ABCB6 in mitochondrial membranes caused the cells to make more porphyrin, the building b...With record resolution and sensitivity, tool images how life organizes in a cell membrane
...sis, exocytosis, all these processes which involve dynamic reorganizations of membranes.'' The membrane that surrounds a cell or the organelles within cells is made of two layers of phospholipids-microscopic ''lollipops'' with water-loving (hydrophilic) heads that point outward and water-fearing (hydrophobi...Hard-wiring the fruit fly's visual system
...into a certain brain region. This is followed by a dynamic phase where neuronal activity refines the visual map. In contrast, in flies the system seems to be completely hard-wired and only rely on genetic inputs." "The most obvious difference between the insect and vertebrate brain is their size and the nu...Paying attention sets off symphony of cell synchronization
...n of how attention altered neural function. "For dynamic stimuli at the focus of attention, the timing of brain activity became more precisely synchronized with the flickering," said Satoru Suzuki, associate professor of psychology at Northwestern and co-author of the study. The results suggest that att...For crickets, parasitic flies can stop the music
... and fly populations are low. "It might be quite a dynamic thing," she said. "Some years, there’s selection against one, some years there’s selection against the other."...Proteins may behave differently in natural environments
... Southwestern Medical Center in Dallas, found such dynamic behavior in a mutant form of a protein called GroEL, which chaperones or helps misfolded protein molecules fold into the shape that allows them to achieve their purpose in the cells. Misfolded proteins have been implicated in a number of neurodegener...One signal elicits thousands of answers
...all cellular proteins are affected. Therefore, the dynamic phosphoproteome provides a missing link in a global, integrative view of cellular regulation." Mann and his team improved and extended a previously developed technology, which enabled them to identify for the first time all phosphorylations of all...Genome archaeology illuminates the genetic engineering debate
...rs show that plant genomes evolved from a far more dynamic structure than previously believed. Maize dominates domestic agriculture, where approximately 9 billion bushels are produced annually at a value of $30 billion. Corn is an important dietary staple in much of the third world and a bio-fuel source; r...New way of tracking muscle damage from radiation
...nd after radiation therapy; and a technique called dynamic enhanced magnetic resonance imaging (DEMRI) to stu... team made 60 images of the same area, including a dynamic view of what was happening in the muscles during a six-minute period following infusion of gadoliniu...Key to zebrafish heart regeneration uncovered
...n a portion of a zebrafish's heart is removed, the dynamic interplay between a mass of stem cells that forms in the wound and the protective cell layer that covers the wound spurs the regeneration of functional new heart tissue, Duke University Medical Center scientists have found. The scientists further di...Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu
...ications Research Laboratory. "The end result is a dynamic research community response network that can meet the needs of a global response to a global threat such as the avian flu." Much of the nitty-gritty work on the avian flu project will be done by students, at both the graduate and undergraduate lev...Carnegie Mellon University research shows how sensory-deprived brain compensates
..., we want to understand at the molecular level the dynamic between sensory use and neural plasticity," Barth said. ...Scripps research study reveals structural dynamics of single prion molecules
...ts for disease-causing amyloids." To define the dynamic structural details of individual prions, Deniz and his colleagues employed several novel technologies including single-molecule fluorescence resonance energy transfer (SM-FRET) and fluorescence correlation spectroscopy (FCS). Fluorescence resonan...Wired for sound: How the brain senses visual illusions
...illusory second flash is based on a very rapid and dynamic interplay between the auditory and visual cortices of the brain ?on a time scale less than one tenth the blink of an eye." Mishra said. Interestingly, the pattern was very different between individuals who did or didn't see the second flash, indicat...Research finds music training 'tunes' human auditory system
...ationship between the brainstem and neocortex is a dynamic and reciprocal one and tells us that our basic sensory circuitry is more malleable than we previously thought." Overall, the findings assist in unfolding new lines of inquiry. The researchers now are looking to find ways to "train" the brain to b...Sandia researchers take new approach to studying how cells respond to pathogens
...tunity to track proteins and see, for example, the dynamic cellular production of proteins or protein-binding processes inside or on the surface of the cells. The team is developing one platform with two complementary microfluidic modules -- one for trapping and imaging viable cells during stimulation wit...Rare cell prevents rampant brain activity
...s extremely complex network is regulated through a dynamic balance between excitatory signals, which are transmitted by one type of synapse, and inhibitory counter-signals, which are transmitted by another. An imbalance between excitatory and inhibitory activity is associated with diseases such as epileps...Executable biology -- Computer science sheds light on animal development
...to the same cellular signals, so understanding the dynamic orchestration in the cellular environment has impo... computer science to translate this picture into a dynamic representation that can capture time-dependent processes. Results from the model can then be compare...Decoding protein structures helps illuminate cause of diabetes
...ells], which cause disease." To break down this dynamic process, he adds, "We need tools that not only all... The speed is crucial for trying to understand a dynamic process like hIAPP mis-folding, Zanni says. The group now plans to capture series of snapshots ...