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Tag: "duplication" at biology news

Study: Harmless virus kills some cancers

... cancer is by inhibiting the normal process of DNA duplication of human papillomavirus (HPV). HPV is known to lead to cervical cancer. A second way AAV2 suppresses cancer is linked to its ability to slow cell-cycle progression by decreasing cancer cell proliferation rates and causing growth arrest. In this stud...

Big differences in duplicated DNA distinguish chimp and human genomes

...'s even more difference between the species due to duplication events," said Eichler. "Now we need to learn the role of those duplication events in species evolution and disease." The researchers divided the duplications into three grou...

Mosaic mouse technique offers a powerful new tool to study diseases and genetics

...in to divide--a normal process that results in the duplication of each chromosome. Before cell division is complete, a special enzyme causes the exchange, or recombination, of the two engineered chromosomes. If one of those chromosomes contains a bad copy (mutation) of a gene, the recombination event could cause...

Unchecked DNA replication drives earliest steps toward cancer

...ess. This stress leads to random errors in the DNA duplication process ?breaks in the DNA that disrupt genes, for example. Unless halted, this error-generating process leads to an accumulation of mutant genes in the cell and, eventually, cancer. A report on the new findings appears in the April 14 issue of Natu...

Defensins neutralize anthrax toxin

... normally regulates the cell-cycle progression, or duplication process, of resting B cells. In the presence of this viral protein ?called EBNA3C (for EBV nuclear antigen) ?the cell cycle of the usually quiescent human B cells gets a jump start, which ultimately initiates uncontrolled growth. EBV, a member of th...

Epstein-Barr virus protein crucial to its role in blood cancers

... normally regulates the cell-cycle progression, or duplication process, of resting B cells. In the presence of this viral protein ?called EBNA3C (for EBV nuclear antigen) ?the cell cycle of the usually quiescent human B cells gets a jump start, which ultimately initiates uncontrolled growth. EBV, a member of th...

Scientists document complex genomic events leading to the birth of new genes

...at had evolved more than one copy in humans. "Gene duplication is known to play a leading role in evolution for the creation of new genes," explained Francesca Ciccarelli, Ph.D., lead author on the study. The key to this, however, is that the duplicated copies of genes very quickly evolve functions that are sign...

Whole genome fine map of rice completed

...in intergenic regions. The study also analyzed the duplication history of the rice genome. Eighteen pairs of apparent duplications were discovered, covering 65.7% of the genome. Among them, 17 pairs happened before the divergence of the grasses from other flowering plants. More importantly, the on-going duplicat...

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