Tag: "drugs" at biology news

Key Trigger Of Opioid Withdrawal Symptoms Found

...triggers some of the withdrawal symptoms of opioid drugs like morphine and heroin. They believe that drugs to inhibit the chemical--called a transporter--could relieve some of the early physical symptoms of ...

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

...development of new and better clinical methods and drugs hereby reducing mortality and improving quality of life for patients suffering from these diseases. The Karolinska Institutet/Affymetrix Translational medicine research projects will use sufficiently large sample sizes to establish true clinical rel...

Implanted Devices Detect High-Risk Heart Failure Patients

...ve years of diagnosis. Although there is no cure, drugs can improve the strength of the heartbeat (digoxin), relax blood vessels (ACE inhibitors)or remove the excess buildup of fluid in the lungs (diuretics). Implantable devices are the latest options in preventing arrhythmias that can lead to sudden deat...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...n to play a role in responses to alcohol and other drugs of abuse. Using DNA microarrays, which measure the... alcohol consumption. If researchers can identify drugs that may inhibit or activate the function of one of the genes identified in these studies, they may ...

Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis

...se including RNAi, microRNA, DNA-based and aptamer drugs and represents a substantial portion of the cost t...s, and the eventual development of oligonucleotide drugs that are affordable to patients,?stated Dr. Kenji Matsumoto, President of Kinovate Life Sciences, In...

Antibiotic might fight HIV-induced neurological problems

...t job of controlling HIV in blood, but most of the drugs don't cross the blood-brain barrier very well," sa...mates, and HIV only infects people. Antiretroviral drugs target and interfere with the viral proteins needed to accomplish this. In contrast, minocycline do...

Protein offers way to stop microscopic parasites in their tracks

... identified a protein that could help them develop drugs to stop or slow cell invasion by malaria and other parasites known as apicomplexans. Results of the study will appear in the March 15 issue of Proceedings of the National Academy of Sciences. Scientists identified the new protein in the protozoan pa...

Effective Cancer Treatments Follow The Clock

...anism that explains why sensitivity to anti-cancer drugs changes with the clock. They said their findings c... said, “as they provide a rationale for developing drugs that can enhance the therapeutic index through the modulation of the circadian clock. We have alread...

Potential treatments for neurofibromatosis

...vessels. The IU investigators now are identifying drugs that can disrupt the function of mast cells and th...he genetic instability common to tumors. By using drugs that target the mast cells' ability to promote blood vessel growth, Clapp and his colleagues hope to...

World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics

...ly to tell," he says. The recipients use the same drugs to prevent organ rejection as are used in the Edmonton Protocol. Dr. Shapiro was invited to participate in the operation in Kyoto, Japan, where he originally did living donor liver transplant training with Dr. Tanaka. Dr. Masumoto was previously bas...

Use of PET can reduce, may eliminate more strenuous drug development trials with animals

...euticals, possibly speeding the way for innovative drugs to patients, said Welch. Since there is no public ...ore of an understanding about titanium anti-cancer drugs and new techniques for PET imaging with 45Ti, which they found to have excellent imaging characteris...

Drug-resistant bacteria on poultry products differ by brand

...ut fluoroquinolones are some of the most important drugs used to treat a variety of infections, including t...n proposed to withdraw approval of fluoroquinolone drugs for use in poultry production. That effort has since been stalled by legal objections from Bayer, on...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

... in maternal and fetal organs. "Understanding how drugs are transferred between a mother and her fetus during pregnancy may help us unravel the mechanisms of the drug's damaging effects on unborn children," said SNM member Helene Benveniste, M.D., Ph.D., chair of Brookhaven's medical department in Upton, ...

Probing the promise and perils of nanoparticles

...rimers have shown promise for precisely delivering drugs to their targets inside the body, but high concent...ycationic polymers---already being used to deliver drugs and genes---to see if they behaved like dendrimers. "It turns out that they cause the same permeabil...

Chemists identify immune system mechanism for methamphetamine binges

...ickerson, Ph.D., also a chemist at Scripps. Other drugs of abuse, including nicotine and ecstasy (which is structurally similar to methamphetamine), might share a similar mechanism of action involving immune system recognition and a consequent rise in tolerance to the drug, Janda and his associates theori...

Molecular models advance the fight against malaria

..., paves the way for using these models to test new drugs that could suppress malaria's ability to mutate ag...ars. Although atovaquone is one of the most recent drugs on the market, there is significant evidence that malaria parasites are quickly developing resistanc...

Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

...pproach to the development of cholesterol-lowering drugs that may boost the effect of statins, one of the m... to the researchers. The new findings suggest that drugs that mimic lanosterol--given along with statins--may improve the drugs' long-term ability to lower c...

Stopping smallpox in its tracks: A new anti-viral approach

...cilitates viral replication. This study shows that drugs that interfere with erbB-1 signaling inhibit SPGF-induced viral replication and spread. The authors show that treatment with these erbB-1 inhibitors are effective in lowering morbidity and mortality, and boosting T cell immunity, in infected mice. I...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...have sounded the alarm: There simply aren’t enough drugs to combat bad bugs. Bacteria are increasingly adep...tions such as high cholesterol or diabetes, not in drugs designed to be used for a week or two and then stopped once an infection clears, he said. Now UF re...

FDA Clears the Way for Generic Versions of Transdermal Patches to Treat Chronic Pain

...bstance, which is the highest level of control for drugs with a recognized medical use. As a controlled sub...tion (DEA), which administers the CSA. Schedule II drugs are subject to manufacturing quotas set by DEA with input on medical need from FDA, distribution tra...

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