drug 2 9

Tag: "drug" at biology news

Widely used hepatitis B drug spurs HIV drug resistance

...stablished medical practice that an antiretroviral drug widely used to treat hepatitis B liver infections ...prescribing physicians can be notified and so that drug labeling can be changed. They have also notified Bristol-Myers Squibb, which makes and sells enteca...

A potential biological cause for sudden infant death syndrome

...fy infants at risk for SIDS. They also envision a drug or other type of treatment to protect infants who have abnormalities in their brainstem serotonin system. The brainstem serotonin system is thought to help coordinate breathing, blood pressure, sensitivity to carbon dioxide, and temperature durin...

Stress hormones may play new role in speeding up cancer growth

... to both norepinepherine and epinephrine. With the drug present, the levels of MMP-2, MMP-9 and VEGF didn't increase. "This suggests a new approach to possibly fight some cancers ?the prescribing of beta-blocker-type drugs that would block these receptors and perhaps slow the progression of the disease...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...ne, shows that using an LVAD combined with certain drug therapies can shrink the enlarged heart and enable it to function normally once the LVAD is removed. For the study, researchers from Imperial College London and the Royal Brompton and Harefield NHS Trust gave the full combination therapy to 15 se...

St. Jude announces breakthrough in eye cancer treatment

...ample of local delivery of a targeted chemotherapy drug for any childhood cancer, Dyer said. Targeted therapy uses a customized drug to disable a specific molecule inside a growing cancer cell; local delivery is the placement of a dr...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...ase the lifespan of obese mice, and found that the drug reversed nearly all of the changes in gene expression patterns found in mice on high calorie diets--some of which are associated with diabetes, heart disease, and other significant diseases related to obesity. The research, led by investigators at Ha...

Free drug samples influence prescribing, say one in three doctors

One in three doctors agree that free drug samples influence prescribing, finds a small but r...ght it was ethical to accept free samples of a new drug from a pharmaceutical company rep. Similarly, just over half thought it was ethical to accept a l...

One-of-a-kind imaging probe reveals secrets useful for drug discovery

...t's the kind of thing that may provide hints about drug discovery in future." More than 40 years ago, Jerrold Meinwald, Ph.D., an emeritus professor of chemistry and chemical biology at Cornell University, led landmark chemical studies of walking stick venom. He was pleased to know the insect was being s...

Lungs try to repair damaged elastic fibers

...portant because it could pave the way to develop a drug to 'turn on' key genes to allow the lung to grow new alveoli, he said. Alveoli play a role in the exchange of oxygen and carbon dioxide between the lungs and the circulatory system. A 2-year-old could do it Very young children who suffer lung i...

Why don't all moles progress to melanoma?

...ic for tumor cells, which could be used for future drug development," she says. ...

UCSF study will test new vaginal microbicide for herpes and HIV

...us by the FDA. Fast track status is granted when a drug has the potential to treat a serious or life-threatening condition and demonstrates the potential to address unmet medical needs for that condition. ...

Mutant gene causes severe kidney disease in infants

... can do high-throughput screening of many possible drug candidates for this form of nephrotic syndrome." Note for parents and physicians: Information on genetic testing for infants with early-onset nephrotic syndrome is available at www.renalgenes.org ....

Bacteria in small sea life yield new way to make potential cancer drugs

...nd how changing genes can lead to changes in small drug molecules. "The promise of genes is that you ca...ce greater quantities of compounds for testing and drug development. E. coli is a good producer of compounds, but yields are not yet practical. ...

Solution to bacterial mystery promises new drugs

...uld block is not used by humans. Therefore, such a drug would not cause dangerous side effects. A report on this finding appears in the September 1 issue of Molecular Cell. The discovery also demonstrated that current textbooks use the wrong type of bacterium as a model to explain a critical biochemica...

Male contraception: One door opens, another closes

...e name Zavesca) (Human Reproduction, Oct. 25). The drug is already FDA-approved and on the market in both Europe and the United States for treatment of a rare genetic disorder, Gaucher disease. So scientists were very excited when they realized that it was acting as a contraceptive in their male mice at a...

Einstein researchers demonstrate a novel approach to treating AIDS

...ts from the treatment. "Today's antiretroviral drug therapies can inhibit the multiplication of HIV and help prevent HIV from infecting additional cells," says Dr. Harris Goldstein, Director of the Center for AIDS Research at Einstein. "But we currently have no way of eliminating the HIV-infected cell...

Researchers seek to design first treatment for neuroAIDS

...eceived a $7 million grant to confirm that two new drug classes can protect the brain from HIV-related ner...antagonists, NMDA antagonists like the Alzheimer's drug Memantine, platelet activating factor (PAF) inhibitors, and in the case of the new grant, drugs that...

Increase in drug development for killer diseases is not enough

A recent report shows that drug development for killer diseases such as HIV/AIDS, ...he George Institute will be discussing the rise of drug development for neglected diseases and the role of PPPs at a major international conference, organis...

Heart smart: new drug improves blood flow

A new drug has been shown to improve blood flow in diseased a...njunction with Bayer Health Care, hopes to use the drug as part of a revolution in the management of heart disease. Dr. Harald Schmidt, Director of the Ce...

New brain-chemistry differences found in depressed women

...essed women were then prescribed an antidepressant drug and reported regularly about their depression symp...pain treatment. The technique uses a form of a drug called carfentanil, which binds to the same receptors on the surface of brain cells that brain chemi...

1 2 3 4 5 6 7 8 9 10