drug 2 7

Tag: "drug" at biology news

Susceptibility to Crohn's disease -- an important new clue

...y paving the way towards personalized medicine and drug target identification. ...

Re-analysis of cigarettes confirms tobacco companies increased addictive nicotine 11 percent

...frey Ferris Wayne. "Cigarettes are finely-tuned drug delivery devices, designed to perpetuate a tobacco...that the companies have been subtly increasing the drug nicotine year by year in their cigarettes, without any warning to consumers, since the settlement. S...

Health Canada approves cold and flu medicine

...y profile of COLD-fX with no known side effects or drug interactions for generally healthy individuals. ...ral health product regulations are also similar to drug regulations with requirements for standardized labeling, good manufacturing practices, and specifica...

Scientists uncover new target in cancer mutation puzzle

... that the way to develop rational searches for new drug targets is to first understand how these oncogenes cooperate. And in this study we've shown for the first time that this idea might work." Land was among the scientists in the mid-1980s who first discovered oncogene collaboration. Since then, his ...

Brain networks strengthened by closing ion channels

...tions. This discovery may help the development of drug therapies for the cognitive deficits of normal aging, and for cognitive changes in schizophrenia, bipolar disorder, or attention deficit hyperactivity disorder (ADHD). "Our data reveal how the brain's arousal systems influence the cognitive networ...

Knocking out survival protein could aid leukemia treatment

..., a new study shows. The findings suggest that a drug that can block this "survival protein" might on its own be an effective therapy. But such a drug used in combination with several existing drugs might also offer an effective one-two punch against ...

Statin plus cancer drug deliver combo punch to brain cancer cells

...ination of a hedgehog blockade and a pro-apoptosis drug like lovastatin would kill more cancer cells. "O... said he was "surprised by the degree to which the drug combination was so effective." According to Eberhart, only half of children with medulloblastoma ...

Resistance to anti-HIV drugs in Uganda developed due to drug supply problems

...etroviral medications experienced interruptions in drug supply due to either financial demands or supply l...ngs do highlight the need for strong logistics and drug supply management in any antiretroviral therapy program as well as continued monitoring of adherence...

New research may overturn conventional wisdom on drug-resistant tuberculosis

..., China and elsewhere, used molecular genetics and drug susceptibility testing to investigate patients wit...tients. To determine the relative proportion of drug resistance caused by re-infection or mutation, the authors excluded six patients who were initially ...

Primitive yeast yields secrets of human cholesterol and drug metabolism

...rt controls cholesterol production and potentially drug metabolism. The collaborative study by investigat... of enzymes required for cholesterol synthesis and drug metabolism,?says Peter Espenshade, Ph.D., assistant professor of cell biology at Johns Hopkins. “We’...

Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu

...or use in virtual screening for new inhibitors and drug discovery. CNIC will also become the central repository for the project’s research data. The database will be distributed through the computational data grid, and accessible through web portals mirrored at partner sites. "The availability of a...

Lead-'scrubbing' drug may also improve muscle function in lead-exposed children

...) is a technique, nicknamed “scrubbing,?in which a drug is administered to seek out and bind to poisonous ...metals. Succimer (Chermet) is an oral chelating drug approved by the Food and Drug Administration to treat children with extremely elevated blood lead le...

Leukemic cells find safe haven in bone marrow

The cancer drug asparaginase fails to help cure some children with...kemic cells survive treatment with asparaginase, a drug that normally would deplete their supply of this vital nutrient, the researchers reported. Mesenchym...

Morphine makes lasting -- and surprising -- change in the brain

...inued to be blocked 24 hours later ?long after the drug was out of the animal’s system. "The persistence of the effect was stunning," Kauer said. "This is your brain on drugs." Kauer recorded the phenomenon in the ventral tegmental area, or VTA, a small section of the midbrain that is involved in th...

Reminding doctors which antibiotics to prescribe cuts C. difficile infection rates

...ry 2-3 months on how many courses of each specific drug they had prescribed, and ward rates of CD infection and MRSA. Doctors' prescriptions were compared before the policy change (September 1999-June 2001) and afterwards (July 2001-March 2003). A statistically significant drop in use of both cephalosp...

New dopamine brain target discovered

...lex by its unique reaction to dopamine or specific drug triggers. Strikingly, stimulating this target with dopamine or specific drugs triggered a rise in calcium in the brain. As calcium has a profound effect on almost all brain function, this rise in calcium causes a cascade of events in the brain. Thi...

Brown team finds crucial protein role in deadly prion spread

...veal a way to control the spread of prions through drug intervention. If a drug could be made that inhibits this fragmentation process, it could substantially slow the spread of pr...

Bird flu -- Call for antiviral drugs to be shared

...a flu virus by many months, to the benefit of both drug donors and recipients. ...

New nanotechnology able to examine single molecules, aiding in determining gene expression

...ng is used widely in basic biological research and drug discovery," said Jason Reed of UCLA's Department of Chemistry and Biochemistry and the study's lead author. "Scientists have been hampered in their efforts to unlock the secrets of gene transcription in individual cells by the minute amount of materi...

Anti-dandruff compound may help fight epilepsy

...of restoring normal nerve cell activity. “Most drug discoveries uncover chemicals that stop things from working - it’s a lot easier to close or block a door than open it,?Li says. “But here we found a chemical that makes a defective protein work better. So now we have a chance to actually try to fix t...

1 2 3 4 5 6 7 8 9 10