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Tag: "drug" at biology news

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...could determine how an individual might respond to drug or radiation therapy. Molecular predictors of drug response in breast cancer: Abstract 4963 Researchers at Lawrence Berkeley National Laboratory h...

Biologists prove critical step in membrane fusion

...e ?there is the potential to control the timing of drug delivery. ...

No carrier necessary: This drug delivers itself

...ative solution in which the delivery system is the drug itself. They describe for the first time in Molecular Pharmaceutics a drug delivery system that consists of nanocrystals of a hydrophobic drug. The system involves the use o...

Natural gut hormone offers hope for new obesity drug

...e found naturally in the gut is the basis of a new drug to tackle obesity, one of three inaugural awards u...ome Trust's Seeding Drug Discovery initiative. The drug is being developed by one of the world's leading obesity experts, Professor Steve Bloom at Imperial ...

New antibacterials being developed to tackle MRSA superbug

...s a form of the bacterium that is resistant to the drug methicillin and a number of other antibiotics and ...terial population should be extremely low if a new drug was to emerge from this programme. "The antibiotic that we are developing is far more selective th...

OHSU lab finds meth receptor that could lead to therapy

...e-by-side, using their combined skills to identify drug targets and to design new drugs to treat diseases like drug addiction," said David Dawson, Ph.D., OHSU professor and chairman of physiology and pharmacology. "C...

Growth hormone is not the anti-aging bullet for healthy adults

...ti-aging falls into a grey area. The FDA prohibits drug companies from marketing GH for off-label uses suc...n of patients. The FDA typically doesn't approve a drug until it's been tested in thousands of patients. "In our review, we found that growth hormone inc...

Gene expression test reveals ER and HER-2 status of breast tumors

...tive are sensitive to Herceptin, an antibody-based drug that binds to the HER-2 receptors, blocking them from coupling with growth factors that fuel breast cancer. Last fall, the group published a study showing that a genomic microarray test can also predict a patient's response to chemotherapy. They a...

Scientists create dual-modality microbeads to improve identification of disease biomarkers

... in samples taken at later dates, then we know the drug is probably working." This new technology allows the researchers to analyze very low concentrations of target molecules. "Instead of analyzing a liter of sample where the concentration could be very dilute and you might not see the target molecule...

Antivirals effectively curb influenza virus

...l and combined estimates from two studies for each drug were used in both instances. Furthermore, oseltamivir treatment of ill persons did not appear to reduce the frequency of influenza infection in their contacts. In exploring the reasons for oseltamivir's greater effects on infectiousness, the autho...

Sunshine pill for prostate cancer in 2009

...rly as 2009. But it remains to be seen whether the drug will be the revolution in prostate cancer care tha...the on-going phase III trial goes to plan, the new drug should be available in 2009, reports Chemistry & Industry, the magazine of the SCI. 'If the ...

New synthetic self-assembling macromolecules mimic nature

...ed structures could have potential applications in drug delivery and gene delivery systems." But more immediate, "These unique block copolymers can be instructive models in understanding the forces that lead to the dense packing of DNA when complexed with viruses and other polymers," he said. ...

Molecular signature may identify cisplatin-sensitive breast tumors

...-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast ...negative tumors might be sensitive to cisplatin, a drug used to treat several other types of cancer, but whether the more common sporadic triple-negative tu...

Researchers hot on the trail of brain cell degeneration

...he calcium, in the hope of finding new targets for drug design. The object of the study, the Rho protein, belongs to a family of proteins able to influence signals that had been linked to cell degeneration. The two teams' analysis demonstrated that over-stimulation causes activation of Rho as well as ...

Stem cell transplants explored at Stanford as a possible treatment for hearing loss

...ord from Harvard, he's been focused on two paths: drug therapy -which could be as simple as an applicati...ut we first have to find it." The idea of using drug therapy to cure deafness has been at the back of Heller's mind since he began researching the inner...

Researchers discover surprising drug that blocks malaria

...eveloping world, is resurging worldwide because of drug resistance and the lack of an effective vaccine, H...or the malaria parasite to develop resistance to a drug that acts on a person's red blood cells as the blood pressure medication does, Haldar said. When ...

Cancer researchers add spice to research against rare neuromuscular disease

...e to see if the compound could be developed into a drug to help people with the disease, scientists say it's a promising development in a field where progress has been slow. The research by scientists at the University of Rochester Medical Center appears in the March 6 issue of the journal Nature Medic...

Discovery of an HIV inhibitor in human blood points to new drug class

..., and a growing number of HIV strains are becoming drug resistant. HIV resistance to one drug can lead to resistance to other drugs in the same class, a phenomenon known as crossresistance. "...

Small molecule dervived from Rb2/p130 could act as cancer therapeutic

...pound, it can be easily reproduced as a biological drug in large quantities and does not require potentially dangerous means of delivery like viruses, as do most gene therapies; therefore Spa310 has a good chance to succeed as an anti-cancer therapy. For these reasons, he believes it may be easier to get...

Scientists perform 'tricky' operation

...milies of interest, particularly those involved in drug resistance. "The completion of the genome seque...complete genome dataset the search for alternative drug targets can really take-off." Amazingly, the pesky parasite was found to have an exceptionally la...

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