drug 2 4

Tag: "drug" at biology news

In obesity, brain becomes 'unaware' of fat

...rongly validate?SOCS-3 as a target for antiobesity drug development. ...

Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising

...my of Sciences. The effort to create needle-free drug delivery systems is driven by a combination of fac...ers), delivering only 2 to 15 nanoliters of liquid drug at a time. The research showed that the pulsed microjet system could be used to effectively deliver ...

Study finds antibiotic resistance in poultry even when antibiotics were not used

...n May in the same journal ?also examined levels of drug resistant campylobacter bacteria, a common foodbor...biotic-free commercial group were resistant to the drug oxytetracycline, for example, while 90 percent were resistant to the drug in a commercial flock that...

Mutation improves memory, may lead to memory-enhancing pill

...int to a potential target for the development of a drug to treat memory loss, according to the researchers...octoral fellow in Sonenberg’s laboratory. "While a drug that worked in this way wouldn't cure the disease itself, it might rescue the symptoms of memory los...

Navigable nanotransport

... the contents of the capsule, such as an antitumor drug or contrast agent, can be released to selectively attack the tumor or to make an unambiguous diagnosis. ...

Major gene study uncovers secrets of leukemia

...o multiply, causing ALL. "If we could design a drug that bypasses the roadblock to differentiation, we could push these cells to become fully mature B lymphocytes," Downing said. "And then the body would recognize them as defective B lymphocytes and destroy them." ...

Penn researchers show how nanocylinders deliver medicine better than nanospheres

... they were able sustain delivery of the anticancer drug paclitaxel to an animal model of lung cancer ten t...ped carriers. These findings have implications for drug delivery as well as for better understanding cylinder-shaped viruses like Ebola and H5N1 influenza. ...

Cambodian vulture nests offer hope for species

...tire range due to Diclofenac, an anti-inflammatory drug used for cattle that is highly toxic to vultures. Diclofenac has lead to global population declines as high as 99 percent in slender-billed and other vulture species. Diclofenac is now being slowly phased out in South Asia, but not at a pace that as...

Brown cancer biologists identify major player in cell growth

...and stop division, there is the possibility that a drug can be made to do the same thing in cancer cells." ...

Enhancing activity of marijuana-like chemicals in brain helps treat

...reitzer, PhD, the study's lead author, combined a drug already used to treat Parkinson's disease with an... the other cells didn't. The researchers tested a drug called quinpirole, which mimics dopamine, in mice with a condition similar to human Parkinson's di...

NT researchers discover breakthrough in malaria treatment

...ents for malaria. Both contained a combination of drug based on a Chinese herbal extract (artemisinin) wi...ne of the first to highlight the best treatment of drug resistant strains of vivax malaria found in the Asia pacific region." said Dr Price. "It also pro...

Bacterial walls come tumbling down

The first detailed images of an elusive drug target on the outer wall of bacteria may provide s...d by antibiotics, progress in turning up bona fide drug targets has been slow. The cell wall enzymes in particular have tantalized scientists, Strynadka sai...

Drug-resistant bacterial infections serious complication after corrective eye surgery

...spital strains, which usually demonstrate multiple drug resistance. Community-acquired MRSA is becoming a significant problem, with the prevalence of MRSA among community isolates expected to reach as high as 25% in the next decade. The authors cite the case of a male nurse who underwent an "uneventful...

Hybrid molecule causes cancer cells to self-destruct

...ctioning. Efforts to use butyrate as a general drug for tumors elsewhere in the body, however, have been hindered by the high doses of the compound needed to effectively eradicate cancer. To get around this problem, scientists have tried to make butyrate more potent by modifying it or joining it to ot...

Misusing vitamin to foil drug test may be toxic; plus, it doesn't work

... doses of a common vitamin in an attempt to defeat drug screening tests may send the user to the hospital—... as vitamin B3, in mistaken attempts to foil urine drug tests. Both adult patients suffered skin irritation, while both adolescents had potentially life...

Columbia scientists determine 3-dimensional structure of cell's 'fuel gauge'

...e energy. AMPK provides an especially promising drug target for people with type 2 diabetes. These patients are insulin-resistant, meaning that their cells are not responsive to insulin which normally helps glucose get out of the bloodstream, where it does damage, and into cells. When AMPK detects low...

Genes set scene for metastasis

...t cancer cells). The researchers conclude that drug combinations that target one or more of the proteins encoded by these genes may prove useful for treating metastatic breast cancer. ...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...the investigators then gave the mice a simple oral drug that permitted the amount of enzyme provided by the engrafted stem cells to work even more efficiently by presenting them with a smaller burden of material to metabolize. The lifespan of the mice doubled. (Neither treatment could work as effectively ...

Synthetic peptide targets latent papilloma virus infections

...ell divides. If such a peptide - or more likely, a drug that mimics the action of the peptide - works in t...antitative Biology (QB3). "The hope is to have one drug that works for all different human virus types." "The second most preventable cancer in the world,...

A genetic 'gang of 4' drives spread of breast cancer

... Massagué said that while clinical trials of the drug combination are being discussed, "there are alread...ry carefully to understand how and whether the new drug combination would be of additional benefit." In the article published in the Proceedings of the Nati...

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