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Tag: "drug" at biology news

Potent possibilities for parasite attack

...sent a limited repertoire of potential targets for drug and vaccine development allowing researchers to op... have been in use for more than half a century and drug resistance is rife, creating a desperate need for new treatments. Biological studies for the functio...

UCF nanoparticle offers promise for treating glaucoma

...rsity of Central Florida is proving promising as a drug delivery device for treating glaucoma, an eye dise... barrier making it an effective non-toxic tool for drug delivery,” said Sudipta Seal, an engineering professor with appointments in UCF’s Advanced Materials...

Weizmann Institute scientists develop a general 'control switch' for protein activity

...red protein by increasing or reducing it. When the drug is no longer applied, or when it is removed from t...creened to identify the ones that respond to the drug in a desired manner. The researchers have discovered that in some of the engineered proteins the dru...

Fat fish put obesity on the hook

...ltimately increase the efficiency and power of the drug discovery process, thus bringing new medicines to the market faster and cheaper.” In the study, researchers caused obesity in zebrafish by introducing the same type of genetic mutation that causes severe obesity in humans. The genetic change block...

Researchers identify protein pathway involved in Parkinson disease development

...t cellular function and could provide a target for drug therapies to treat the disease. The research by a team of Emory University scientists will be published June 18 in the Public Library of Science Biology (PLoS Biology) journal. Parkinson disease is a degenerative disorder of the central nervous s...

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

... which they achieve or do not realize benefit from drug therapy) beginning at three months following surgery and continuing through the end of the study. These improvements occurred predominantly on the side of the body corresponding to the side of the brain receiving treatment. Moreover, the absence of c...

Modified mushrooms may yield human drugs

...at we are doing is taking a gene, as for example a drug gene, that is not part of the mushroom, and camouf...t require expensive infrastructure set up by major drug companies, he added....

St. Jude study shows genes play an unexpected role in their own activation

... manipulate CREB’s co-factors to treat disease. “A drug that blocked the specific co-factors CREB needs in the liver to trigger activity of genes that make glucose could reduce blood levels of this sugar in people with diabetes,” Brindle said. “But at the same time, CREB could continue its other jobs with...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

... To date, treatment of arthritis is dominated by drug treatments like non-steroidal, anti-inflammatory drugs, COX-2 inhibitors and acetominophen. Morphine and its derivatives are still in common use as well, but can depress breathing and lead to addiction. Taken together, current treatments deliver inco...

'Smart' mice teach scientists about learning process, brain disorders

...-traumatic stress disorder, Alzheimer’s disease or drug addiction, the researchers said. "It’s pretty rare that you make mice ‘smarter,’ so there are a lot of cognitive implications," said Dr. James Bibb, assistant professor of psychiatry and the study’s senior author. "Everything is more meaningful...

Treating HIV in war zones -- Public health emergencies need rapid advice from WHO

...e: Providing patients with extra emergency drug supplies that can be taken in case of program interruption. Stockpiling emergency supplies of ART and securing them against vandals and looters Distributing clinics widely throughout the treatment area, thus reducing travel requirements and makin...

New designer lipid-like peptide with lipid nanostructures for drug delivery systems

...tures, will offer unique characteristics like high drug load capacities and low viscosity. Here these de...eptides may play a key role in improving effective drug delivery systems....

Common treatment for methamphetamine overdose may damage brain cells

A common antipsychotic drug used in emergency rooms to treat methamphetamine o...or methamphetamine overdose in humans might worsen drug abuse-related brain injuries," says William Carlezon, PhD, at Harvard's McLean Hospital, who was not...

An 'elegant' idea proves its worth 25 years later

...e immediate clinical success of the treatment, the drug combination was finally approved by the U.S. Food and Drug Administration only in 2005. Brusilow, Hamosh, and colleagues at Stanford University, University of Minnesota, Thomas Jefferson University and the Medical College of Wisconsin looked back...

Human stem cell treatment restores motor function in paralyzed rats

...muscle spasticity is continuous systemic or spinal drug treatments using implanted pumps. These approache...are often accompanied by side effects and eventual drug tolerance that lessens their efficacy. “These research findings could offer great hope to people ...

Resistant HIV quickly hides in infants' cells

... been made in limiting transmission with antiviral drug therapies before, during, and following birth. In...ission affects the responses of infants to various drug treatments. The study, conducted by Deborah Persaud, MD, of Johns Hopkins University School of ...

Hearts of male and female rainbow trout are different

...loroacetate, an activator of PDH and a therapeutic drug used to treat human heart disease and cancer), or (c) glucose + NaCN under oxygenated and hypoxic conditions. The researchers measured several indices of contractile performance (resting tension, twitch force, post-rest potentiation and other var...

Peramivir protects mice from lethal H5N1 infection

The antiviral drug peramivir might offer humans significant protectio... injections of peramivir daily for eight days. The drug also inhibited replication of the deadly strain of H5N1 virus in the lung, brain and spleen. The key...

8 plants from South Africa may hold potential for treating high blood pressure

...iverse in the world. In South Africa, 21st century drug therapy is used side-by-side with traditional African medicines to heal the sick. While plants have been used in African medicine to treat fever, asthma, constipation, esophageal cancer and hypertension, scientific analyses of the purported benefits ...

Targeting sugar on blood vessels may inhibit cancer growth

... factors that support angiogenesis. An antibody drug called Avastin, produced by Genentech, has been sh...), thus inhibiting the growth of vasculature. The drug has been used along with chemotherapy in humans to successfully inhibit the growth of tumors in colo...

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