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Tag: "drug" at biology news

Transplanted brain cells hold promise for Parkinson's disease

...e to five years. As the disease progresses and the drug becomes less effective, doses are increased and can produce more dyskinesia, loss of controlled movement. Centers such as MCG are exploring new ways to slow disease progression, diagnose it earlier and more accurately monitor its progression....

Gene therapy inhibits epilepsy in animals

...rchers later injected the rats with pilocarpine, a drug that causes status epilepticus (SE), a convulsive ... does, however, lay the foundation for a potential drug therapy that might act on the same signaling pathways, to prevent epilepsy after a brain insult such...

Scientists show drug can counteract muscular dystrophy in mice

...have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice ...thy mice. "This is the first example of using a drug to counteract muscular dystrophy in mouse models," says Dr. Sartorelli. Yet he points out that the ...

Scientists discover way to block growth of prostate cancer cells

...development of prostate cancer. They found that a drug that blocks this pathway significantly prolonged s...cer and die of the disease. The hope is that this drug could be used eventually to treat men at high risk of developing prostate cancer and to prevent recu...

A valuable fly for research into disease

Cancer, drug addiction, neurodegenerative diseases, epilepsy, i... and heart disease "What can a fly tell us about drug addiction?" is the title of a talk by the University of California's Ulrike Heberlein, a pioneer in ...

Hair-growth drug artificially lowers PSA levels in prostate cancer screening, study finds

The popular hair-growth drug finasteride, taken by millions of balding men, art...lligram per day, patients who take the finasteride drug Proscar for BPH get a five times higher dosage, 5 mg per day. "The impact of finasteride on PSA leve...

HIV-1 kills immune cells in the gut that may never bounce back

... (or HAART) in 1995. In fact, most patients on the drug regimen do so well that, according to blood tests,...re is eye-opening." After three years of intensive drug therapy that suppresses HIV replication very effectively, most patients still had only half the norm...

New drug blocks influenza, including bird flu virus

...e infected animals treated with small doses of the drug at the onset of symptoms survived. "Pretreatment... The scientific team emphasized that while the new drug shows great promise, much work remains to determine optimal dosage, efficacy and safety before the d...

Fantastic Voyage: A new nanoscale view of the biological world

...r to find where and how much of a cancer treatment drug there is within a cell. New technology described in a study published today in the open access journal Journal of Biology makes it possible to image and quantify molecules within individual mammalian or bacterial cells. Claude Lechene and colleagues ...

To slow AIDS in Russia, treat HIV-positive addicts, Stanford study says

...ating AIDS in Russia may be to treat HIV-infected drug users. A new model estimating the spread of HIV in Russia suggests that treating injection drug users with antiretroviral medication will slow transmission of the virus among the general populat...

Origin of inherited pain disorder pinpointed

...unctioned. What's more, the researchers found, the drug carbamazepine—known to be effective in PEPD—acts t...man inflammatory pain and explain the differential drug sensitivity of PEPD and PE." ...

Molecules in blood foretell development of preeclampsia

...ans to produce a form of VEGF. Presumably, such a drug would raise the levels of circulating VEGF in the ...autioned, however, that such attempts to develop a drug treatment would need to proceed cautiously. It's possible that restoring normal blood pressure and ...

LSD treatment for alcoholism gets new look

... that indicate a single dose of the hallucinogenic drug LSD, provided in a clinical, nurturing environment...oholism. The Saskatchewan group argued that the drug needed to be provided in a nurturing environment to be effective. However, the Toronto researchers h...

Studies look at how genes affect antipsychotic drug response

... Bishop said if children are to receive long-term drug therapy, clinicians need to make sure they are app...tic prescriptions in pediatric psychiatry. Adverse drug effects, such as weight gain and the possibility of prolactin elevation, are often dose-limiting and...

Cocaine high caused by interference in neuronal receiving stations

...yperactivity and intensive sniffing and biting the drug elicits in the animals. They found that drugs that either activated the D2R subunit or inactivated the NR2B subunit tended to enhance such behavioral responses to cocaine. "These results provide strong evidence supporting a critical role of the D2R...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

... Sugden expects is achievable, is to end up with a drug that kills only EBV-positive tumor cells and doesn't harm other tissues in the body. ...

Environmental toxins may cause body's defenses to worsen lung disease

...se pathways could play an important role in future drug treatments for patients with chronic obstructive pulmonary disease and the basic scientific findings may also have applications in asthma and cystic fibrosis as well as other chronic lung diseases. The overall goal of the study is to expand existing...

Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses

...ent of last resort for those who do not respond to drug therapy. But nearly one in 10 of those treated se...formation makes the enzyme a legitimate target for drug therapies to block its production and action. "If we can selectively shut down the antiparasite ...

Natural protein stops deadly human brain cancer in mice

...BMP4 could begin within a year and, if successful, drug therapies could be available to the public within three to four years. "This was proof of the idea that BMPs could stop glioblastoma by depleting the stem-cell-like population that feeds it," says Henry Brem, M.D., chairman of the Department of Neu...

BC catalyst discovery promises faster, cheaper drug production

... a problem: often, one hand, or enantiomer, of the drug molecule can be beneficial to a patient's health, while the other may be harmful. Because of this, it is important for anyone who wants to prepare drugs, especially in large quantities, to be able to synthesize single-handed compounds with high sel...

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