Ancient retrovirus sheds light on modern pandemic
...s, such as HIV-1," Emerman said. "In the end, this drove human evolution to be more susceptible to HIV." For example, the researchers found that changes in TRIM5a that make it better at fighting HIV actually inhibit its ability to stop PtERV1 and vice versa, which indicates that this antiviral gene may onl...Killing the messenger RNA -- But which one?
... to about double its normal levels. This, in turn, drove levels of uric acid up to about two times what they should be. "This confirmed that our original computer prediction of differential targeting by unedited and edited microRNAs of different sets of genes is likely to be correct," Nishikura says. "A...First biomarker for human sleepiness identified in fruit flies
...ls in response to these drugs, they found caffeine drove amylase activity up while methamphetamine did not. Flies dosed with the herbicide paraquat did not have increased amylase levels, suggesting changes in amylase activity were not related to stress. Flies lacking the gene for amylase had normal slee...Successful lung cancer surgery not enough to break nicotine dependence in many smokers
...acy" for quitting, he says. "The thing that really drove whether or not people relapsed is whether they saw smoking as pleasurable and rewarding to the point that they can’t do without cigarettes, and they don’t believe they are able to quit." Patients who were able to quit by the one year mark waited l...Ancient global warming drove early primates' dispersal
...ed and indicates that sudden, rapid global warming drove the dispersal. Researchers from the University of Michigan, Johns Hopkins University School of Medicine and the Royal Belgian Institute of Natural Sciences present their findings in the July 25 issue of the Proceedings of the National Academy of S...One in 14 men having a heart attack drive themselves to hospital
Seven per cent of men having a heart attack drove themselves to hospital and only 60 per cent went b...ed. But only one per cent got behind the wheel and drove to the hospital. "Driving during a heart attack is obviously extremely dangerous for both the drive...Infused spleen cells found not to impact islet recovery and reversal of type 1 diabetes in mice
...e because the DNA sequences differ too much. That drove the Hopkins researchers to seek and develop this new system, by which virtually any DNA sequence can be tested for its ability to turn on a marker gene in zebrafish embryos. The system is a significant advance over current methods in this model speci......e because the DNA sequences differ too much. That drove the Hopkins researchers to seek and develop this new system, by which virtually any DNA sequence can be tested for its ability to turn on a marker gene in zebrafish embryos. The system is a significant advance over current methods in this model speci......the differences were due to natural selection that drove significant sequence changes in the lineage leading to humans. These changes accumulated presumably because they conferred some competitive advantage. The evidence that Microcephalin and ASPM were evolving under strong natural selection in the linea...