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Tag: "drive" at biology news

FSU biologists describe key role of signal-transcribing gene during cell cycle

...ng of just how and where molecular mechanisms that drive cell cycle behavior and fate go wrong along the critical Notch pathway ?? a communication channel already associated with the genesis of several genetic and neuromuscular diseases; the most common complex congenital heart disorder; and later life ill...

Cyberkinetics, Case to develop system to help restore extremity function

...enerate command signals. The command signals would drive a hybrid FES-orthosis, an orthotic device for the upper limbs, designed to provide the user with thought-controlled arm and hand movement through the use of the patient's own muscles. The purpose of the device will be, ultimately, to restore voluntar...

Study provides insight into cellular defenses against genetic mutation

...BP80 works by activating a protein factor known to drive NMD called human up-frameshift (hUpf) protein 1. ...t come together at exon-exon junction complexes to drive NMD review. The three up-frameshift proteins work together to trigger decay once an early nonsense c...

Genomatix Microarray Analysis Pipeline achieves Affymetrix GeneChip compatible?status

...xon array technology, I expect that our tools will drive far greater understanding of genomic organization and transcriptome regulation." "Affymetrix is pleased to be working with Genomatix in their efforts to develop advanced tools for analyzing GeneChip data," said Steve Lincoln, vice president of Infor...

Micro RNAs play role in egg making

...te large amounts of specific proteins necessary to drive the amazing structural changes seen in embryogenesis. In addition to Carthew and Minden, other authors on the PNAS paper are Kenji Nakahara and Kevin Kim of Northwestern University and Christin Sciulli and Susan Dowd of Carnegie Mellon University. ...

Computer modeling reveals hidden conversations within cells

...is the almost circular way the model's predictions drive the design of new experiments, and the how results of those experiments can be fed back into the model to improve it," said Shannon Werner, a graduate student in chemistry and biochemistry, who did the experimental work described in the paper. Once ...

Scientists create digital bacteria to forge advances in biomedical research

...s that cells use for propulsion, and the motors to drive them. Emonet and his associates have designed their digital bacterial system in modules, so that additional components may be added later. "Right now it's a very simple model," Emonet said. "Basically the only thing those cells have is a sensory sy...

Hanging baskets of sex and death help fruit growers

...s at the University of Warwick to harness the sex drive of a major pest of fruit orchards as a weapon to spread a virus to kill that very same pest. The device allows growers to selectively target the pest with a virus that kills its larvae without killing other beneficial insects. The researchers a...

Once given 'no respect,' cells' tiny RNAS take driver's seat

..., if disturbed, has the potential to very potently drive cell growth and cancerous proliferation." Among the genes Myc controls is one called E2F1, which, like Myc, also controls the expression of genes. One of the genes controlled by E2F1 just happens to be the gene for Myc. "This establishes a feedback...

Insight into our sight: A new view on the evolution of the eye lens

...sferred to frog embryos, these regulatory elements drive gene expression in the tadpoles' own visual system, including the lens. This strongly suggests that prior to the evolution of the lens, there was a regulatory link between two tiers of genes: those that would later become responsible for controlling ...

Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades

...s. "Such distortions to international food markets drive down prices and have often seriously undermined the livelihoods of food producers in many poorer countries." "These practices eventually lead to decreased land productivity and a downward spiral of worsening degradation and poverty," says Prof. Safr...

Researchers track down cause of a disfiguring bone disorder

...-base-pair conserved region named ECR5 was able to drive SOST expression. "This study represents a clear and unambiguous case in which altering noncoding genomic content has a deleterious impact on gene expression," the team reported, "demonstrating that mutations in distant regulatory elements are able t...

International Team Determines Geographic Origin of Leprosy

... Aggressive therapy with multiple drugs has helped drive down the number of registered leprosy cases around the world, notes Dr. Sizemore. However, despite drug treatment, the number of new cases of leprosy detected each year has stayed the same or risen. The new understanding of the genetic makeup of the ...

First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology

...Health. "This new technology has the potential to drive down drug manufacturing costs, which could make medicines and health insurance plans less expensive for all of us." ...

Motor transport in bio-nano systems

...ong very thin rod-like filaments and, in this way, drive the heavy traffic of molecular cargo within biological cells. Both motors and filaments can be isolated from the cells and used to construct biomimetic transport systems. In order to increase the flux of the cargo transport, it would be necessary to ...

The making and breaking of microtubules

...ulin leads to far-reaching structural changes that drive microtubule growth." Building a microtubule: Microtubules are polymers whose basic units are pairs (dimers) of similar but not identical tubulin proteins, dubbed the alpha and beta forms. During polymerization the dimers stack end to end to make a ...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

...tute only a portion of all the genetic errors that drive the disease. Our work provides a good starting point for scientists looking for others." As part of the study, investigators did microarray analyses on the two major subtypes of NSCLC, adenocarcinoma and squamous cell carcinoma, and found that their...

Key to elephant conservation is 'in the sauce'

...hum and millet; and as an ingredient in a spray to drive away animals. In addition, chillies are currently being used in the production of bottled hot sauces, jams and relishes. Proceeds from these products are donated to the trust to support to the development of chilli growing projects. "This is a high...

Agilent Technologies introduces advanced zebrafish, mouse microarrays for stem cell and developmental biology research

...ark attack does occur, it makes big headlines. The drive you will make to the beach is far more dangerous, but an auto accident that kills several people will not make big headlines across the U.S. But a shark attack on one person will." According to the International Shark Attack File, only seven fatalit...

New HIV drug candidate developed in Sweden

...ark attack does occur, it makes big headlines. The drive you will make to the beach is far more dangerous, but an auto accident that kills several people will not make big headlines across the U.S. But a shark attack on one person will." According to the International Shark Attack File, only seven fatalit...

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