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Tag: "drastically" at biology news

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...h so many more receptors on their surfaces, became drastically more responsive to the naturally occurring painkil...nclude amplifying the body’s response to morphine, drastically reducing the amount needed for powerful pain relief," Tallents said. "A little further out, the new ...

Want to save polar bears? Follow the ice

...mselves, but the receding sea ice habitat that may drastically shrink as a result of global warming. In a project named "Warm Waters for Cool Bears," WCS will use both current and historical satellite imagery to predict where sea ice is likely to persist and where subsequent conservation efforts to save the spec...

New success in engineering plant oils

...?to know that we can change the oil composition so drastically by simple specific changes in seed oil metabolism, and that this process can occur independently from the adaptation to either tropical or temperate climates." For example, such a technique could lead to the engineering of temperate crop plants to...

Jefferson scientists find rabies-based vaccine could be effective against HIV

...ferson Medical College in Philadelphia have used a drastically weakened rabies virus to ferry HIV-related proteins into animals, in essence, vaccinating them against an AIDS-like disease. The early evidence shows that the vaccine ?which doesn’t protect against infection ?prevents development of disease. Report...

Synthetic peptide targets latent papilloma virus infections

While a newly marketed vaccine promises to drastically reduce human papilloma virus (HPV) infections, the major cause of cervical cancer, a new discovery by University of California, Berkeley, researchers could some day help the millions of people already infected and at constant risk of genital warts an...

Gene therapy for blindness clears hurdle in mice

...of rhodopsin by about 60 percent. With the gene drastically muzzled, scientists have begun experiments to create a therapy in which healthy versions of the gene can be introduced into the eye using an apparently harmless virus to deliver the genetic material. "If we reduce the amount of protein formed by m...

Dual gene therapy suppresses lung cancer in preclinical test

...ene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice, researchers at The University of Texas M. D. Anderson Cancer Center and the University of Texas Southwestern Medical Center report in the Jan. 15 edition of Cancer Resear...

Stretching DNA to the limit

...y a plateau region. This characteristic plateau is drastically reduced in width with increasing exposure to UV light. UV light induces the crosslinking of the constituent DNA bases within the polynucleotide chains, as well as causes the formation of lesions by linking together the adjacent strands. The small ...

With fruit fly sex, researchers find mind-body connection

... didn't completely remove the gene's influence but drastically reduced it. The result: Flies' sexual equipment was intact, but, theoretically, their sexual behavior might be different. McKeown and graduate student Troy Shirangi also reduced the activity of the fruitless gene as well as one called "retained." ...

Tearing down the fungal cell wall

...estigators show that disruption of the AbNPS2 gene drastically impacts the integrity of the cell wall of fungal spores produced in the reproductive phase of A. brassicicola's life cycle. The AbNPS2 gene most likely directs the synthesis of a molecule that plays an essential role in maintaining the structure of t...

The power of one: A simpler, cheaper method for cell fusion

...ly fuse cells in parallel. "In time, this could drastically increase the rate of cell fusion," he said. Lu has shown that his technology has a success rate comparable to current technology; about 30 percent to 40 percent of the cells are properly fused when the operational parameters were tuned up. "We ...

Plant-derived molecules, genetic manipulation point to future chemoprevention methods

...ice that lacked a gene that ultimately resulted in drastically reduced IGF-1 in the livers of mice had nearly half the number of tumors seen in mice with normal IGF-1 levels. Specifically, they found that mice with normal IGF-1 levels had an average of 13 colon tumors, but the IGF-deficient mice had only 7.2 tum...

Climate change has surprising effect on endangered naked carp

... a surprising 70 percent, and urine flow decreases drastically to less than 5 percent of its rate in the freshwater river water. "In other words, the kidney changed from an organ which excreted water at a greater rate than salt in river-water, to one which conserved water relative to salt in lake-water," expl...

A wolf in sheep's clothing: Plague bacteria reveal one of their virulence tricks

...cent survival rate, showing that Prehna's mutation drastically lowered Yersinia's harmful effects. "Altering this binding site not only impairs the bacteria's ability to disrupt the host cytoskeleton," Stebbins says, "but it decreases its virulence significantly." "It's rare to find something that has such a st...

Three-in-one virus killer prevents common, often fatal infections

A novel combination therapy drastically reduces the infection rate of three viruses ?and risk of death ?in transplant patients with compromised immune systems. The findings, to be reported in the Nov. 1 print edition of Nature Medicine, originate from a study conducted at Baylor College of...

UBC researchers find stroke death channel

...tside the junction and leak chemicals. The process drastically disrupts levels of critical brain cell ingredients such as calcium and potassium, and is associated with rapid cell death. Every year, 50,000 Canadians suffer a stroke. Another 300,000 people are living with the consequences of stroke, which ...

Researchers attack tumor cells by exploiting dependency on sugar metabolism

...ion of LDH-A stimulated mitochondrial function and drastically compromised the ability of the tumor cells to proliferate in low oxygen conditions. Restoration of LDH-A activity reestablished the glycolytic phenotype of the tumor cells. These data suggest that alterations in glucose metabolism in cancer cells ar...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...er tumor cells, stifling a troublesome protein and drastically reducing the size of tumors, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 15 edition of Clinical Cancer Research. The mouse model experiment, featured on the cover of the journal, demonstrates a potent deli...

Insect predation sheds light on food web recovery after the dinosaur extinction

...ng from instability, incumbency and opportunism in drastically simplified ecological landscapes," say the authors. ...

Delft water-purification method promises radical improvement

...nology research has discovered a method that could drastically change the way we purify water within a few years. Delft, in partnership with DHV engineering bureau, has developed a compact and environmentally-friendly purification method, in which aerobic bacteria form granules that sink quickly. An important pa...

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